(ZA9304351-A)      The use of biomass (A) obtd. in the fermentative prepn. of lipase inhibitors (I), esp. lipstatin (Ia) is claimed in the prepn. of foods, feedstuffs, food or feedstuff additives, supplementary feedstuffs, feedstuff-medicament premixes or orally administered medicaments.    Also claimed are foods, feedstuffs, food or feedstuff additives, supplementary feedstuffs, feed-medicament premixes or oral medicaments which either: (a) contain (A), opt. added to water-insoluble crude fibres; or (b) contain (I), esp. (Ia) or tetrahydrolipstatin (Ib), added to water-insoluble crude fibres.    USE/ADVANTAGE -   (I) inhibit enzymatic cleavage of fats in the body, and are added at 0.1-100 (pref. 1-50) mg (opt. as (A)) as dietary additive to feedstuffs (esp. for dogs or cats) to prevent or treat adiposity and optimise the wt. of the animal. (A) also contains valuable protein and fat, and can replace animal and/or vegetable constituents of the feed. Use of (I) with fibre further reduces fat resorption. Dose of (I) plus fibre reduces resorption of fat in the feedstuff by 1-100 (esp. 40-70)%. Feeds contg. (I) or (A) are acceptable to animals and adequately satisfy hunger. (A) or (I) can also be used in meat animals (to promote formation of low-fat musculature) or humans.    (US5447953-A)      Treatment of adiposity comprises admin. to a non-human mammal a biomass comprising a lipase inhibitor. Biomass is obtained by fermenting a broth contg. microorganisms producing the lipase inhibitor, and sepg. the biomass from the broth. Lipase inhibitor is lipstatin or esterstatin.    USE/ADVANTAGE -   Treatment of adiposity in animals e.g. cats and dogs. Dosage is 0.1-100 (1-50) mg lipase inhibitor fat. Admin. is orally via a feed or as an additive to feed supplements or drugs. No need to train the animal to a different feed. Animal does not suffer from residual hunger.    (EP575846-B1)      The use of biomass (A) obtd. in the fermentative prepn. of lipase inhibitors (I), esp. lipstatin (Ia) is claimed in the prepn. of foods, feedstuffs, food or feedstuff additives, supplementary feedstuffs, feedstuff-medicament premixes or orally administered medicaments.    Also claimed are foods, feedstuffs, food or feedstuff additives, supplementary feedstuffs, feed-medicament premixes or oral medicaments which either: (a) contain (A), opt. added to water-insoluble crude fibres; or (b) contain (I), esp. (Ia) or tetrahydrolipstatin (Ib), added to water-insoluble crude fibres.    USE/ADVANTAGE -   (I) inhibit enzymatic cleavage of fats in the body, and are added at 0.1-100 (pref. 1-50) mg (opt. as (A)) as dietary additive to feedstuffs (esp. for dogs or cats) to prevent or treat adiposity and optimise the wt. of the animal. (A) also contains valuable protein and fat, and can replace animal and/or vegetable constituents of the feed. Use of (I) with fibre further reduces fat resorption. Dose of (I) plus fibre reduces resorption of fat in the feedstuff by 1-100 (esp. 40-70)%. Feeds contg. (I) or (A) are acceptable to animals and adequately satisfy hunger. (A) or (I) can also be used in meat animals (to promote formation of low-fat musculature) or humans.