NOVELTY - Removing restriction from drain pipe system by introducing cleaning composition containing non-caustic drain opening active, activating composition by adding liquid, allowing active to remain in contact with restriction for sufficient time to degrade restriction and rinsing active from system.    USE - The methods and compositions are useful for clearing clogged and slow running drains.    ADVANTAGE - The method effectively removes soil deposits over the entire intyerior surface of the drain pipe thereby reducing the number of times a drain need be treated. The composition is pH insensitive and economical and easy to use. The compositions can be produced by current manufacturing and filling methods.    DETAILED DESCRIPTION - A method of removing restriction from a drain pipe system comprises: introducing to drain pipe system having an an organic restriction a cleaning composition comprising a foaming gas generation/entrapment carrier and non-caustic drain opening active comprising bacteria for waste or sewer treatment in an amount of 0.1-50 wt% of the composition. The carrier comprises, prior to combination with water, an alkali carbonate, an acid and a foaming surfactant; activating the cleaning composition by adding a sufficient amount water to the pipe system while maintaining a flow-through state in the pipe system, whereby the carrier causes the drain opening active to become imbedded in the restriction; allowing the active to remain in contact with the restriction for a sufficient time to degraade the restriction; and rinsing the active and restriction from the pipe system. The method improves water flow rate of the pipe system by an average of at least 0.7 l/minute after 16 hours of the active contacting the restriction. INDEPENDENT CLAIMS are also included for: (1) A method of removing restriction from a drain pipe system as above in which the non-caustic drain opening active comprises, instead of bacteria for waste and sewer treatment, at least one reducing agent an amount of 1-90 wt% of the composition; and (2) A method of removing restriction from a drain pipe system as above in which the non-caustic drain opening active comprises, instead of bacteria for waste and sewer treatment or reeducing agent, at least one peroxygen compound in an amount of 1-90 wt% of the composition.