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PROTEIN SCIENCE, vol. 5, no. 12, December 1996 (1996-12), pages 2416-2428, XP000978804 ISSN: 0961-8368;  OTSUKA K: "Regeneration of NADH and ketone hydrogenation by hydrogen with the combination of hydrogenase and alcohol dehydrogenase" JOURNAL OF MOLECULAR CATALYSIS, vol. 51, no. 1, 1989, pages 35-39, XP000946525 ISSN:0304-5102 cited in the applicationEP1621613-A1  OTSUKA K: "Regeneration of NADH and ketone hydrogenation by hydrogen with the combination of hydrogenase and alcohol dehydrogenase" JOURNAL OF MOLECULAR CATALYSIS, vol. 51, no. 1, 1989, pages 35-39, XP000946525 ISSN:0304-5102;  ABRIL O ET AL.: "Hybrid organometallic/enzymatic catalyst systems: Regeneration of NADH using dihydrogen" JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 104, no. 6, 1982, pages 1552-1554, XP002148357;  BHADURI S ET AL: "Coupling of catalysis by carbonyl clusters and dehydrigenases: Redution of pyruvate to L-lactate by dihydrogen" JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 120, no. 49, 11 October 1998 (1998-10-11), pages 12127-12128, XP002148358 DC US