TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Catalyst: The metal salt or complex may comprise iron, ruthenium, osmium, cobalt, rhodium, iridium, nickel, palladium, platinum, or copper.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The metal salt or complex may comprise one or more ligands, e.g. a phosphine residue, a phosphite residue, carbon monoxide, a cyclopentadienyl residue, an aromatic residue, a halide, or a hydride. A preferred ligand may comprise 1,3-5-triaza-7-phosphaadamantane or a salt of tris(m-sulfonatophenyl)phosphine. The nicotinamide cofactor may comprise NAD+, NADH, NADP+, NADPH or a mixture. The unsaturated organic compound may comprise:(i) a ketone, an aldehyde, a carboxylic acid, a carboxylic acid ester, or an amide;(ii) an alpha-beta unsaturated derivative of a ketone, an aldehyde, a carboxylic acid, a carboxylic acid ester, or an amide;(iii) a fatty acid, a monoglyceride, a diglyceride, or a triglyceride, having an olefinic unsaturated group;(iv) an olefin, an aromatic compound or a heteroaromatic compound; or(v) an imine, or an oxime.The oxidoreductase enzyme may be stabilized with a phosphine or phosphite, e.g. phosphorus derivatives RPn(O-R)3-n, where n is 0 - 3, the R groups comprise optionally substituted hydrocarbyl, aromatic or heteroaromatic groups, one or more R groups may be substituted with one or more polar groups.    TECHNOLOGY FOCUS - POLYMERS - Preferred Ligand: The ligand may have a polar functional group e.g. an anionic group, a cationic group, or a poly(alkylene glycol) group.    TECHNOLOGY FOCUS - BIOLOGY - Preferred Method: The unsaturated organic compound may be a sugar, an amino acid, a peptide, or a protein, where the sugar, amino acid, peptide, or protein has an unsaturated group. The NCDE may comprise 2,5-diketo-D-gluconic acid reductase or glucose-6-phosphate 1-dehydrogenase. EXAMPLE - An 80 milliliter bottle with a micro-liquid sampling tube was charged with 20 milliliters of a 0.1 Molar phosphate buffer (pH = 7.0), 2-heptanone (100 microliters), Tris(m-sulfonatophenyl)phosphine trisodium salt (TPPTS) (74 milligrams), NADP+ (10 milligrams) and alcohol dehydrogenase of Thermanaerobium brockii (TBADH) (2.7 milligrams) under a flow of argon. Ruthenium catalyst (Cl2Ru(TPPS)2)2 (17 milligrams) was finally added and the bottle was sealed, evacuated and filled with 70 psi of H2. Evacuation and refilling with H2 were repeated 2 times and the apparatus was then heated to 60 degrees Centigrade with an oil bath. After 10 hours GC analysis of a microsample removed via the liquid sampler showed the production of 227.8 micromol of 2-heptanone. After an additional 4 hours an additional 13.0 microliters had accumulated (240.8 micromol). The pressure was released from the bottle and a liquid sample analyzed by chiral GC showed the 2-heptanol to be 70.5 percent (S) and 29.5 percent (R) (41.0 percent ee). Turnovers of catalyst components: NAPD+TO = 18.4.