TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The HCS reactor operates at 150-320 degrees C; pressure of 5.5-42 bar and hourly gas space velocities for syngas of 100-40000 V/hour/V. (C) is obtained by removing a portion of (C) from the operating HCS reactor to a regeneration vessel and subjecting the removed catalyst to a regeneration environment to form (C). (C) is removed on a continuous or semi-continuous basis and is filtered to remove at least a portion of reactants and products prior to entering the regenerative environment. The filtration is accomplished by H2 stripping.    TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: (C) is at least one metal selected from Group VIII metals of the Periodic Table (preferably iron (Fe), nickel (Ni), cobalt (Co) or ruthenium (Ru)) or is a bimetallic catalyst. The first catalyst of the bimetallic catalyst is at least one metal selected from Group VIII metals (preferably Fe, Ni, Co or Ru, especially Co) and the second catalyst metal is at least one Group VIIa or VIII element of the Periodic Table (preferably rhenium (Re), Ru, platinum (Pt) or palladium (Pd), especially Re or Ru). The environment is an oxidizing environment that operates at greater than 300 degrees C. EXAMPLE - Fresh Co-Re catalyst on titania (TiO2) support was activated and placed in Fischer-Tropsch reactor. Two samples were removed as early-run sample, which were removed a few days after the reactor was in operation and a late-run sample, which was removed very late in the run cycle. Each sample was removed to a dry box and the wax extracted with hot toluene under inert conditions. Each sample was divided into two portions. The first portion of each sample was directly transferred under inert conditions in a chemisorption unit. The second portion of each sample was regenerated at 350 degrees C in an oxidative environment and then reduced in the presence of H2 at 225 degrees C. The second portion of each sample was then transferred under inert conditions into chemisorption unit. It was observed that hydrogen chemisorption values for non-regenerated early-run catalyst were higher as compared to non-regenerated late-run catalyst, which indicated that the early-run catalyst was rejuvenated under reduction conditions. The late-run catalyst was not rejuvenated due to long-term deactivation mechanism that was not removed by hydrogen catalyst. Fresh catalyst measured after 375 degrees C H2 reduction and 150 degrees C air oxidation had hydrogen chemisorption value of 3.7-4.1. The late-run catalyst activity after regeneration was increased after regeneration by high temperature oxidation followed by low temperature reduction demonstrating that the regeneration/in situ reactivation process reversed the majority of long-term deactivation effects. The oxidation regeneration followed by low temperature H2 treatment restored almost all of the catalytically active sites present in the fresh catalyst.