TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: (II) is a liquefied gas, preferably of b.pt. more than -25 degrees C (especially more than 0 degrees C), specifically isobutane and/or isopentane. (III) is a betaine, sulfosuccinate or sarcosine derivative. (IV) is a 4-18C (preferably 6-18C) medium chain triglyceride and (V) is a 12-24C (preferably 18-22C) fatty acid; the (IV)/(V) mixture especially comprises caprylic/capric triglycerides and oleic and/or linoleic acid. (VI) is an optionally partially or completely hydrogenated phospholipid, a lysophospholipid and/or a ceramide, specifically a compound of formula (VI') or its salt.R1 = 10-20C acyl;R2 = H or 10-20C acyl; andR3 = H, 2-trimethylammonioethyl, 2-aminoethyl, 1-5C alkyl (optionally substituted by one or more of COOH, OH and NH2), inositol residue or glyceryl.Preferred Composition: (A) is an oil-in-water microemulsion having a particle size of less than 200 (preferably less than 100) nm. Lipophilic (I) are dissolved in the discontinuous phase of (A); and water-soluble (I) are dissolved in the aqueous phase and/or retained at the discontinuous phase/aqueous phase interface. (A) is specifically contained in a 1- or 2-chamber aerosol spray container together with a compressed or liquefied gas (especially compressed nitrogen) as propellant. EXAMPLE - A microemulsion preconcentrate comprising 11% lecithin, 48% Miglycol 812 (RTM; caprylic/capric triglycerides), 34% Tween 80 (RTM; polyoxyethylene sorbitan fatty acid ester), 5% propylene glycol and 2% vitamin E acetate was prepared by dissolving the lecithin in the triglyceride, adding the other components and stirring to give a clear homogeneous mixture. A microemulsion, containing 0.1% vitamin E acetate and comprising 5% of the preconcentrate and 10 mM phosphate buffer (pH 6) to 100%, was prepared by adding the preconcentrate to the aqueous phase under stirring at 50 degrees C. A self-foaming oil-in-water microemulsion, containing 0.1% vitamin E acetate and comprising 96% of the above microemulsion, 4% Rewopol SB FA (RTM; disodium lauroyl sarcosinate; foam former) and suitable amounts of isobutane/isopentane and compressed nitrogen, was prepared by adding the foam former to the microemulsion, filling the mixture in a single chamber aerosol container and supplying the isobutane/isopentane and compressed nitrogen. The average particle diameter of the non-foamed microemulsion (containing no foaming agent) was 28.3 nm and the average particle diameter of the foamed and refluidized microemulsion was 32.2 nm.