NOVELTY - Screening (M1) ginsenoside Rb1-like substance or a composition containing ginsenoside Rb1-like substance comprises measuring, estimating or analyzing binding of sugar chain with glycolipid and/or glycoprotein.    USE - (M1) is useful for screening ginsenoside Rb1-like substance. (I) is useful as a pharmaceutical composition for preventing or treating cranial nerve disease, neurotrauma, disease which causes apoptosis or apoptosis like-cell death, as pharmaceutical composition for prevention or treatment of organic disease which causes histopathological change, for treatment of wound (thermal burn), for prevention of disease which causes blood flow obstruction, as a skin external preparation composition, a cosmetic composition, skin endermosis, an additive composition for carrying out trauma by freezing, for cryopreserving tumor cells, immortalized cells, cells or tissues, a composition for hair-growth and for restoration of hair, a physical or chemical peeling agent composition, a mucous-membrane external preparation composition, composition for animal or plant growth regulation, a fertilizer or fodder composition, a composition for preventing malignancy, and a composition for suppressing metastasis for treatment, composition for freezing, for preserving sperm, ovum, a non-reproductive cell, and a non-tumor cell, comprising (I), and as a composition for cryopreservation of non-tumor cells such as astrocyte and a skin keratinocyte. (All claimed.)    ADVANTAGE - (M1) enables screening of ginsenoside Rb1-like substance or composition containing ginsenoside Rb1-like substance efficiently.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following:    (1) ginsenoside Rb1-like substance or composition (I) obtained by (M1);    (2) composition for preventing or treating cranial nerve disease, neurotrauma, disease which causes apoptosis or apoptosis like-cell death, where the composition is administered intravenously, pharmaceutical composition for prevention or treatment of organic disease which causes histopathological change, for treatment of wound (thermal burn), for prevention of disease which causes blood flow obstruction, skin external preparation composition, cosmetic composition, skin endermosis, additive composition for carrying out trauma by freezing, for cryopreserving tumor cells, immortalized cells, cells or tissues, pharmaceutical composition for local administration, composition for hair growth and for restoration of hair, physical or chemical peeling agent composition, mucous membrane external preparation composition, composition for animal or plant growth regulation, fertilizer or fodder composition, composition for preventing malignancy and composition for suppressing metastasis for treatment, where all of the above mentioned compositions comprise (I) and a carrier;    (3) composition for freezing, for preserving sperm, ovum, a non-reproductive cell, and a non-tumor cell, comprising (I); and    (4) composition for cryopreservation of non-tumor cells such as astrocyte and a skin keratinocyte, comprising (I).