TECHNOLOGY FOCUS - MECHANICAL ENGINEERING - Preferred Component: The heat exchange system includes an integrated catalyst-heat exchanger; or a first heat exchanger (28), integrated catalyst heat exchanger (30), and a second heat exchanger.Preferred Function: The first heat exchanger cools the hydrogen-rich reformate. The integrated catalyst-heat exchanger cools reformate and oxidize carbon monoxide from the first heat exchanger. The second heat exchanger cools reformate from the integrated catalyst-heat exchanger.    TECHNOLOGY FOCUS - CHEMICAL ENGINEERING - Preferred Method: The oxygen is injected into the hydrogen-rich reformate by mixing the oxygen with the reformate. The carbon monoxide is oxidized by cooling the hydrogen-rich reformate when the reformate and oxygen contact the single integrated oxidation reaction region. The method of oxidizing carbon monoxide further comprises cooling the hydrogen-rich reformate when the reformate and oxygen contact the single integrated oxidation reaction region. The reformate is introduced by introducing the reformate to the first heat exchanger at a first temperature; cooling the reformate to the predetermined temperature; introducing the reformate from the first heat exchanger to the integrated catalyst-heat exchanger at the predetermined temperature and having the first content of carbon monoxide; and introducing the reformate at the predetermined temperature from the integrated catalyst-heat exchanger to the second heat exchanger to cool the reformate to a second temperature.Preferred Conditions: The predetermined temperature of reformate is 100-120 degrees Celsius. The first content of carbon monoxide of reformate is about 1.0 vol.% of carbon monoxide. The predetermined stoichiometric oxygen/carbon monoxide ratio is 0.5:1 to 5.0:1. The oxygen is at ambient conditions. The second content of carbon monoxide is about less than 10 parts per million. The second temperature is about 80 degrees Celsius. The first temperature is about 200-300 degrees Celsius. The predetermined temperature is about 100-120 degrees Celsius.