NOVELTY - Proposed method includes grinding, proportioning, mixing, sterilization, granulation of components, saturation of them with micro-elements, sieving and repeated grinding of siftings. Method includes also determination of amount of pathogenic micro-organisms contained in products of 2-4-year decomposition of animal excrements and guano. Fertilizer components are subjected to sterilization by natural bischofite solution of the following formula: MgCl2.6H2O at norm exceeding amount required for destroying pathogens by 20-40% by finely dispersed spraying at continuous delivery of components to sterilizer. At presence of pathogenic components, including Salmonella in 100 g of weighted portion (1-5)x106; (6-10)x106 units and (10-25)x106 units. Decomposition production of cattle manure, pig excrements and guano are decontaminated by natural bischofite solution at density of 1.2-1.4 t/m3 at norm of 60-120; 140-180 and 200-400 l/t respectively. Saturation with macro-and micro-elements in form of ground phosphorite and processed sludge of pickling solutions and waste of metallurgical process is carried out during delivery of components to granulator. Fertilizer production line includes storage reservoir, drum-type separator, proportioner and gaseous heat transfer agent source which are connected by means of transporting units. It is connected with inner cavity of drum-type drier by means of air duct. All these units are connected by means of transporting units in form of pipe lines and worm conveyers. Production line is additionally provided with reservoir for liquid sterilizing agent, pump, pressure gauges, valves and hydraulic main for delivery of natural bischofite solution to sprayers. Production line is provided with bins and proportioners for delivery of macro- and micro-elements in form of ground phosphorite and complex micro-elements from processed sludge of pickling solutions and metallurgical process waste; production line is additionally provided with granulator and additional storage reservoirs which are hydraulically connected with storage reservoir and bioreactor intended for processing effluents by means of pipe lines. These units are mechanically connected with drum-type separators mounted above sterilizer by means of worm conveyers. Sterilizer is made in form of belt conveyer. Located in way of delivery of components above sterilizer conveyer are sprayers for finely dispersed spraying of natural bischofite solution for sterilization of fertilizer components. Belt conveyer is conjugated with granulator.    USE - Farming; preparation of complex organo-mineral fertilizers.    ADVANTAGE - Possibility of producing ecologically pure properly balanced fertilizer.3 cl, 1 dwg, 16 tbl