TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The alcohol comprises methanol or ethanol. The triglyceride oil comprises a vegetable oil comprising rapeseed oil, where the glycerin is continuously or periodically withdrawn. Preferred Process: The molar ratio of alcohol to triglyceride is 3:1-20:1 (preferably 3.5:1-6:1). The reaction time is 2-60 (preferably not more than 4) minutes, and the percent conversion of triglyceride oil is greater than about 95%. The reaction is carried out at supercritical temperature and/or pressure. The reaction of the alcohol and oil is carried out in the presence of a solid catalyst e.g. platinum, nickel, chromium and/or zeolites. The process is a continuous type reaction process or a batch type reaction process. The means for separating at least a portion of the glycerin from the reaction mixture comprises a mechanical separator. The mechanical separator comprises at least one of a centrifuge or a cyclonic separator. The system comprises a plurality of reaction chambers in series. The means for separating at least a portion of the glycerin from the reaction mixture comprises a separator disposed after each reaction chamber. The system further comprises a catalyst for catalyzing the reaction of alcohol and triglyceride oil. The system comprises at least one mechanical separator, a mechanical separating being disposed after each reaction chamber for separating at least a portion of the glycerin from the reaction mixture so as to allow the alcohol and triglyceride oil to form more product. EXAMPLE - Vegetable oil was mixed with 3-6 mol of alcohol per mol of oil and 3-6 g of soluble catalyst per liter of oil. The mixture was maintained at 10-150degreesC and a pressure between ambient and 500degreesC. This mixture was circulated through a mixing chamber and centrifugal separator in a continuous flow-through loop. Glycerin was removed from the mixing stream on a continuous basis. Additional methanol and sodium hydroxide was added as needed to compensate for loss dissolved in the removed glycerin. Processing was continued until glycerin production ceases.