NOVELTY - The system (10) has an ultrasound applicator (18) placed in acoustic contact with an individual to transcutaneously apply ultrasound energy to a targeted body region e.g. abdomen. An electrical signal generating machine (16) is adapted to be coupled to the applicator, and includes a controller (26) to generate electrical signals to operate the applicator during a treatment session to produce ultrasonic energy. The controller generates ultrasound energy at a fundamental frequency laying within a range of fundamental frequencies not greater than about 500 kHz.    USE - System for applying ultrasound energy to a targeted body region e.g. thoracic cavity, abdomen, arms, legs, neck and head, to cause vasodilation and increase tissue perfusion during treatment of myocardial infarction, stroke and vascular disease, myocardial infarction, angioplasty, plastic and reconstructive surgery, maxillofacial surgery, vascular surgery, transplant surgery, cardiac surgery, dental procedure, dermatological test patch, exercise regime and wound healing, in a location such as an emergency room, a catheter lab, an operating room ad a critical care unit of a hospital, a mobile setting e.g. ambulance, helicopter and airplane, a public setting e.g. cruise ship, sports stadium airport, and a private setting i.e. person's home.    ADVANTAGE - The system applies the ultrasound energy to the targeted body region to affect vasodilation and an increase in tissue perfusion without deep heating of tissue due to absorption of ultrasonic energy.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for the following:    (1) a method for treating an acute coronary syndrome    (2) a method for treating heart attack    (3) a method for treating stroke    (4) a method for treating vascular disease    (5) a method for increasing drug uptake    (6) a method for achieving regional systemic therapy.    DESCRIPTION OF DRAWING(S) - The drawing shows a perspective view of a system for transcutaneously applying ultrasound acoustic to affect vasodilation and increased blood perfusion.    Ultrasound energy applying system (10)    Electrical signal generating machine (16)    Ultrasound applicator (18)    Chassis (22)    Controller (26)    Reflux valve/liquid inlet port (62)    Distal connector (80)