TECHNOLOGY FOCUS - BIOLOGY - Preferred Components: The enzyme is covalently coated with lipid groups. The enzyme is lipase, esterase or phospholipase, preferably Candida antarctica, Candida rugosa, Rhizomucor miehei, Pseudomonas sp., Rhizopus niveus, Mucor miehei, Mucor javanicus, Rhizopus oryzae, Aspergillus niger, Penicillium camembertii, Alcaligenes sp., Burkholderia sp., Thermomyces lanuginosa, Chromobacterium viscosum, papaya seeds or pancreatin. The support is capable of binding the enzyme by adsorption or by covalent binding to functional groups. The plant oil is soybean, canola, rapeseed, olive, palm oil, sunflower oil, peanut oil, cotton seed oil, waste cooking oil or any oil triglycerides derived from inedible plant sources.    TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The support is a porous support, which may be organic or inorganic, preferably inorganic support comprising silica or alumina-based supports or organic support comprising polymer-based support, and where the support may optionally contain active functional groups including epoxy, aldehyde groups or ionic groups or the support is an ion exchange resin. The solid support is a hydrophobic solid support.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The lipid epoxide is fatty acids, fatty acid alkyl (preferably methyl) esters, sugar fatty acid esters, medium- and long-chain alkyl glucosides, phospholipids, polyethylene glycol derivatives or quaternary ammonium salts. The organic solvent is: alkanes (including octane, iso-octane or n-hexane), ether (such as di-isopropyl ether), alcohols (such as n-octanol), aldehydes (such as decanaldehyde), ketones (such as 2-octanone), and/or oil triglycerides.    TECHNOLOGY FOCUS - POLYMERS - Preferred Components: The hydrophobic polymeric support is hydrophobic aliphatic and acrylic cross-linked polymers or hydrophobic aromatic cross-linked polymers such as Amberlite XAD 7HP (RTM: Adsorbent resin) and Amberlite XAD 1600 (RTM: Hydrophobic polymer resin), respectively. EXAMPLE - Lipase derived from Thermomyces lanuginosa (1 ml) (Lipozyme TL 100L (RTM: Lipolytic food grade enzyme)) was mixed in a bisolvent system comprising 0.05 M phosphate buffer (1 ml) at pH 6.5, and n-hexane (10 ml) containing a lipid epoxide. The mixture was stirred for 48 hours. A support (1 g) was added into the system and the mixture was stirred for 8 hours. The support containing the modified-immobilized enzyme was filtered off and dried in a desiccator overnight to yield the highly active covalently lipid-coated-immobilized lipase.