TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The catalytic compound is of formula (Mn4O4L6). The support substrate has hydrophobic regions and hydrophilic regions. The water molecules are capable of incorporating in the hydrophilic regions of the substrate. At least some of the catalytic compounds are supported in the hydrophobic regions of the support substrate, and can catalytically interact with water molecules in the hydrophilic regions. The catalytic compounds have the tendency to destabilize in aqueous solution. The ionizable functional compounds are sulfonate compounds. L is a photo-dissociable ligand bound to the core, and a phosphinate molecule. The chemical relay is a photo-electrochemical relay system in the form of a photo-active dye from ruthenium polypyridyl dye.Mn404=manganese-oxo cubane core;andL=ligand stabilizing the core.Preferred Property: The catalyst is capable of catalyzing water according to the cycle of (Mn4O4L6)+ to O2 plus L- plus (Mn4O4L5)2+; and (Mn4O4L5)2+ plus L- 2H2O(4H+ plus 4e-) to (Mn4O4L6)+. Preferred Composition: The catalyst further comprises chemical relay system capable of electrochemically oxidizing the catalytic compounds to assist in the regeneration of the catalytic compounds.    TECHNOLOGY FOCUS - POLYMERS - Preferred Component: The hydrophobic regions are formed by a hydrophobic polymer backbone, and are regions of ionizable functional compounds partially stabilizing intermediate catalytic compound(s) including a positively charged manganese atom. The support substrate is a sulfonated fluoro polymer which stabilizes the binding of the other ligands in the same catalytic compound upon photo-dissociation of one ligand from catalytic compounds to reduce the tendency of the catalytic compound to destabilize in the presence of the water molecules compared to the same tendency to destabilize in aqueous solution. EXAMPLE - Nafion(RTM: perfluoro-sulfonic acid polymer) membrane was immersed in bis(p-methoxyphenyl)phosphinate as cubane catalyst and acetonitrile with a volume ratio of 1:1. The immersed membrane was evaluated for oxidation by voltammetry experiments. Results showed that the membrane was stable, displayed little to no photo-current, and contained 10% (v/v) water.