NOVELTY - Treating at least one disease or condition in an individual comprises: (a) measuring a concentration of at least one anti-inflammatory signal molecule in the individual's blood before exercise; (b) directing the individual in an exercise; (c) measuring a concentration of the anti-inflammatory signal molecule in the individual's blood after exercise; (d) comparing the concentrations of the anti-inflammatory signal molecule; and (e) modifying the exercise to increase the concentration of the anti-inflammatory signal molecule.    USE - The methods are useful for treating diseases and conditions in an individual by providing exercise regimens to increase the concentration of anti-inflammatory signal molecules such as morphine, ACTH, and IL-10. Specifically, the methods are useful for treating cardiovascular diseases, arthritis, pericarditis, vasculitis, lupus, bronchitis, phrenitis, HIV infections, schizophrenia, Alzheimer's disease, Crohn's disease, colitis, diabetes mellitus, autoimmune diseases, toxoplasmosis, asthma, multiple sclerosis, and/or preferably Parkinson's disease (all claimed). Mild exercise programs are particularly useful for inducing the formation of signaling molecules associated with immune, vascular, and neural downregulation.    DETAILED DESCRIPTION - An INDEPENDENT CLAIM is a method of increasing the concentration of at least one anti-inflammatory signal molecule in an individual's blood including an exercise regimen comprising: (a) measuring the individual's resting heart rate; (b) directing the individual in a first aerobic exercise until the individual's heart rate stabilizes; (c) directing the individual to rest until the resting heart rate is achieved; (d) directing the individual in a second aerobic exercise until the individual's heart rate is 10 beats/minute greater than the stabilized heart rate achieved during the first aerobic exercise; (e) directing the individual to rest until the resting heart rate is achieved; (f) directing the individual in a third aerobic exercise such that the heart rate achieved in the second aerobic exercise is achieved in less time; (g) directing the individual to rest until the resting heart rate is achieved; (h) directing the individual in a fourth aerobic exercise until the individual's heart rate is 10 beats/minute greater than the heart rate achieved during the second aerobic exercise; (h) directing the individual to rest until the resting heart rate is achieved; and (i) directing the individual in a fifth aerobic exercise until either the individual's heart rate has plateaued or the exercise has continued for one minute.