TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Process: In the process, before the composition is under a steady-state hydrogenation reaction condition, the catalytic constituent is a first catalytic constituent having a first pre-reaction oxidation state and a first pre-reaction interaction with the substrate selected from ionic charge interaction and/or electrostatic charge interaction; or at least a portion of the first catalytic constituent is modified or displaced to produce a second catalytic constituent having a second pre-reaction oxidation state and a corresponding second pre-reaction interaction with the substrate, where the second pre-reaction oxidation state of the second catalytic constituent is either less than, greater than or equal to the first pre-reaction oxidation state of the first catalytic constituent. The catalytically-active region (at least 50%) is concentrated within a mean thickness of less than or equal to 20 nm. The isoelectric point (IEP) obtained for the nonmicroporous substrate prior to or after a first leaching treatment is less than or equal to 7.8, but greater than 0. Preferred Components: The catalytic constituent is selected from Bronsted or Lewis acids, Bronsted or Lewis bases, noble metal cations and noble metal complex cations and anions, transition metal cations and transition metal complex cations and anions, transition metal oxy anions, transition metal chalconide anions, main group oxyanions, halides, rare earth ions, rare earth complex cations and anions, noble metals, transition metals, transition metal oxides, transition metal sulfides, transition metal oxysulfides, transition metal carbides, transition metal nitrides, transition metal borides, transition metal phosphides, rare earth hydroxides and/or rare earth oxides. The first catalytic constituent is selected from acids, bases and/or chalconides. The second catalytic constituent is selected from palladium, platinum, rhodium, iridium, ruthenium, osmium, copper, silver, gold, rhenium, nickel, cobalt, iron, manganese, and/or chromium. The substrate is a glass composition having a sodium surface area rate of change (SARC-Na) of less than or equal to 0.5. The nonmicroporous substrate is selected from AR-glasses, rare earth sodium silicate glasses, silico boroaluminate glasses, E-glasses, boron-free E-glasses, S-glasses, R-glasses, rare earth glasses, silicate glasses, Ba-Ti-silicate glasses, nitrided glasses, A-glasses, C-glasses and/or CC-glasses. EXAMPLE - No suitable example given.