TECHNOLOGY FOCUS - POLYMERS - Preferred Compound: The liquefied polyethylene glycol compound is polyethylene glycol, polypropylene glycol, block polymer of polyethylene glycol and polypropylene glycol, polyethylene glycol monoether or biester substituted by 1-8C alkyl, and/or polypropylene glycol monoether or biester substituted by 1-8C alkyl. The liquefied polyethylene glycol compound contains organic ester, and volume ratio of organic ester and liquefied polyethylene glycol compound is 0:100-10:90. The organic ester is 1-6C alkyl ester, preferably methanol, ethanol or isopropanol. The unsaturated chiral compound is last chiral olefin compound or last chiral ketone compound. The last chiral olefin compound is substituted acrylic acid, substituted acrylic acid ester, dehydrogenated amino acid, dehydrogenated amino acid ester or enamine. The last chiral ketone compound is alpha -keto ester, beta -keto ester or aryl ester. Preferred Property: The number average molecular weight of polyethylene glycol, polypropylene glycol, block polymer of polyethylene glycol and polypropylene glycol, and polyethylene glycol monoether or biester substituted by 1-8C alkyl and polypropylene glycol monoether or biester substituted by 1-8C alkyl is 200-1000, 200-2000, 200-4000 and 200-4000, respectively. Preferred Composition: The mol ratio of unsaturated chiral compound and catalyst is 100-10000:1. Preferred Catalyst: The chiral catalyst is ligand formed by transition metal and microcapsule chiral phosphine ligand. The transition metal is rhodium or ruthenium. The micromolecule chiral phosphine ligand is R-BINAP, S-Meo-BIPHEP, (S,S)-Et-DuPHOS or R-Phos. The chiral catalyst is (RuCl(R-BINAP)(n-C6H6))Cl, (RuCl(S-5,5'-diaminoBINAP)(n-C6H6))Cl, Rh-(S,S)-Et-DuPHOS, RuCl2((R)-xyl-BINAP)((R,R)-DPEN) or (Net2H2((RuCl(R-BINAP))2Cl3). Preferred Conditions: The reaction is carried out at 0-80 degrees C and 1-100 atmosphere or 1-8 hours. Preferred Method: The reaction product is extracted by ether and/or n-hexane. The recycled catalyst is reused.