TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: In producing fatty acids, the mixture in step (a) further comprises at least one of furfural, phenolics compounds and acetic acid. The mixture in step (a) is obtained from a biomass. The biomass comprises plant biomass. The biomass is obtained from plant or animal waste. The plant biomass undergoes pretreatment by acid hydrolysis and heat treatment to produce the mixture inoculated in step (a). The plant biomass comprises: 10-35% lignin; 15-35% hemicellulose; and 30-60% cellulose. The plant biomass is obtained from at least one selected from the group consisting of: switchgrass, corn stover, and mixed waste of plant. The at least one microorganism strain is an extracellular and/or intracellular cellulase, hemicellulase and laccase enzyme producer microorganism. The extracellular and/or intracellular cellulase producer microorganism is selected from the group consisting of: prokaryote, bacteria, archaea, and eukaryote, and fungi. The extracellular and/or intracellular cellulase producer microorganism is a fungus or bacteria selected from the group consisting of Humicola, Trichoderma, Penicillium, Ruminococcus, Bacillus, Cytophaga and Sporocytophaga, Humicola grisea, Trichoderma harzianum, Trichoderma lignorum, Trichoderma reesei, Penicillium verruculosum, Ruminococcus albus, Bacillus subtilis, Bacillus thermoglucosidasius, Cytophaga spp., and Sporocytophaga spp. The at least one microorganism strain is a fungi. The at least one microorganism strain is Trichoderma reesei (Hypocrea jecorina). The at least one microorganism strain is tolerant to one or more compounds produced by a pretreatment of the biomass, wherein the one or more compounds are selected from the group consisting of: furfural, acetic acid, and other impurities. The at least one microorganism strain has been evolutionarily modified to metabolize pretreated biomass targeted more efficiently and to better tolerate furfural, phenolics compounds and acetic acid as compared to the unmodified wild-type version of the microorganism. The at least one evolutionarily modified microorganism strain produces one or more cellulases, hemicellulases, and/or laccases so that the evolutionarily modified microorganism strain has greater capacity to metabolize cellulose and hemicelluloses with lignin as compared to the unmodified wild-type version of the microorganism. The at least one microorganism strain has been evolutionarily modified by at least one method selected from the group consisting of serial transfer, serial dilution, genetic engine, continuous culture, and chemostat. The method is continuous culture. The at least one evolutionarily modified microorganism strain is an aerobic fungi. The at least one microorganism strain is Trichoderma reesei (Hypocrea jecorina) and has been evolutionarily modified by continuous culture. The at least one microorganism strain has been evolutionary modified for a specific biomass plant. The one or more cellulases is at least one selected from the group consisting of: endoglucanase, exoglucanase, and beta-glucosidase, and hemicellulases and optionally laccase. It further comprises measuring cellulase and/or hemicellulase activity in step (a), and depending on the activity of the enzyme, proceeding to step (b). The inhibition step (b) is performed by one more methods selected from the group consisting of: heat shock, UV exposure, radiation exposure, gas injection, homogenization, and genetic modification of the at least one microorganism prior to step (a) so that growth of the at least one genetically modified microorganism is inhibited when temperature is increased to 45 degrees C. The at least one algae strain in step (c) is selected from the group consisting of green algae, red algae, blue-green algae, cyanobacteria and diatoms. The at least one algae strain in step (c) is selected from the group consisting of Monalanthus Salina; Botryococcus Braunii; Chlorella prototecoides; Outirococcus sp.; Scenedesmus obliquus; Nannochloris sp.; Dunaliella bardawil; Navicula pelliculosa; Radiosphaera negevensis; Biddulphia aurita; Chlorella vulgaris; Nitzschia palea; Ochromonas dannica; Chrorella pyrenoidosa; Peridinium cinctum; Neochloris oleabundans; Oocystis polymorpha; Chrysochromulina spp.; Scenedesmus acutus; Scenedesmus spp.; Chlorella minutissima; Prymnesium parvum; Navicula pelliculosa; Scenedesmus dimorphus; Scotiella sp.; Chorella spp.; Euglena gracilis; and Porphyridium cruentum. The growth of the at least one algae strain in step (iii) is not inhibited by the presence of one or more of lignin, furfural, phenolics compounds, salts and cellulases enzymes and/or hemicellulase and/or laccase. The at least one algae strain in step (c) can grow in one or more conditions selected from the group consisting of: aerobic, anaerobic, phototrophic, and heterotrophic. The at least one algae strain in step (c) has been evolutionarily modified by at least one method selected from the group consisting of serial transfer, serial dilution, genetic engine, continuous culture, and chemostat. The method is continuous culture. The at least one algae strain is Chlorella protothecoides which has been evolutionarily modified by the continuous culture method. The at least one algae strain in step (c) metabolizes the at least one of glucose, cellobiose, xylose, mannose, galactose, rhamnose, arabinose or other hemicellulose sugars, and waste glycerol. The at least one algae strain in step (c) uses acetic acid as a carbon source. Step (c) is under aerobic and heterotrophic conditions, the at least one algae strain uses respiration. In step (c), when the algae using the same amount of carbon source as an organism producing fermentation by-product producer, the method produces up to 10% carbon dioxide. The at least one algae strain in step (c) produces no inhibitory by-product that inhibits growth of the algae. It further comprises (d) recovering the one or more fatty acids from the at least one algae strain. The recovering step (d) comprises at least one selected from the group consisting of filtration-centrifugation, flocculation, solvent extraction, acid extraction, base extraction, homogenization, ultrasonication, microwave, pressing, distillation, thermal evaporation, hydrocracking (fluid catalytic cracking), and drying of the at least one algae strain containing fatty acids. The supernatant recovered in step (d) can be reused. Step (c) further comprises culturing and growing the at least one algae strain under conditions for extracellular and/or intracellular production of at least one compound selected from the group consisting of fatty acids, hydrocarbons, proteins, pigments, sugars, such as polysaccharides and monosaccharides, and glycerol. The at least one compound can be used for biofuel, cosmetic, alimentary, mechanical grease, pigmentation, and medical use production. The at least one algae strain produces hydrocarbon chains which can be used as feedstock for hydrocracking in an oil refinery to produce one or more compounds selected from the group consisting of octane, gasoline, petrol, kerosene, diesel and other petroleum product as solvent, plastic, oil, grease and fibers. It further comprises, after step (d), direct transesterification of cells of the at least one algae strain to produce fatty acids for biodiesel fuel. The direct transesterification comprises breaking the algae cells, releasing fatty acids and transesterification through a base or acid method with methanol or ethanol to produce biodiesel fuel. The at least one algae strain is adapted to use waste glycerol, as carbon source, produced by the transesterification reaction without pretreatment or refinement to produce fatty acids for biodiesel production. EXAMPLE - No example given.