TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: The para-glucosidase and cellulase enzymes completely convert cellulose and oligosaccharides produced from the first enzymatic hydrolysis to monomeric sugars. The cellulose (at least 60, preferably at least 75, especially at least 90%) and oligosaccharides are converted to monomeric sugars. The feedstock is subjected to at least one of activation, extraction, hydrolysis and physical modification prior to the first step. The activation, extraction, hydrolysis and physical modification is produced by at least one of auto-hydrolysis, acid hydrolysis, ammonia activation, disc refining, kraft pulping, organic solvent pulping, hot water pretreatment, ammonia percolation, lime pretreatment, caustic solvent pulping, and alkali peroxide pretreatment, where the activation, extraction, hydrolysis and physical modification involves autohydrolysis that is conducted by steam explosion. The method further involves producing sugar derived products for fermentation or a raw alcohol stream through fermentation using the sugar rich process stream; operating the second enzymatic process under vacuum; passing the feedstock through a disc refiner prior to the first step; and obtaining a recycle stream from the first step and reintroducing the recycle stream into the first enzymatic hydrolysis process, where the portion of the recycle stream is first passed through a disc refiner. The yeast, fungi, bacteria and enzyme inhibiting compound is present during the first enzymatic hydrolysis process and the method further involves operating the first enzymatic hydrolysis process under vacuum of at least 100 mm Hg. The inhibiting compound comprises at least one of furfural, hydroxymethylfurfural, organic acids, phenolic compounds and the method further involves operating the first and second enzymatic hydrolysis processes under vacuum to reduce the level of at least one inhibiting compound. Preferred Components: The low viscosity effluent stream has a viscosity of at least 15 (preferably at least 20, especially at least 50)% lower than that of the feedstock. The first enzyme preparation preferentially acts upon the hemicellulose relative to cellobiose in the feedstock. The first enzyme preparation has hemicellulase activity of 10-90 (preferably 30-90, especially 50-90)% and cellulase activity of 90-10 (preferably 70-10, especially 50-10)%. The hemicellulase enzymes preferentially act upon the beta -1,4 linkage of the xylose residues of xylan and the beta -1,4 linkage of the mannose residues of mannan. The second enzyme preparation preferentially acts on the cellulose and cellobiose relative to xylans in the feedstock; and comprises beta -glucosidase and cellulase enzymes, where the beta -glucosidase and cellulase enzymes preferentially act upon the beta -1,4 linkage of cellobiose and cellulose.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The raw alcohol stream comprises an alcohol 3-22 (preferably 5-22, especially 8-22) vol./vol.%. The alcohol is at least one of methanol, ethanol and butanol. EXAMPLE - No suitable example given.