TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: (I) has a: void volume of at least 75%, preferably at least 97%; measured density of less than 0.20 gm/cm3 or less than 0.10 gm/cm3; volume of 65-525 mm3; and volume of at least 100 mm3, preferably less than 300 mm3. The level of crosslinking is 1-35%. In (I), at least 50%, preferably at least 95% of the cavities at the interior of the particle communicate with the surface of the particle. (I) or mold has a spheroidal, ellipsoidal, cylindrical, prismoidal, disk, pill or tablet shape. The cavities comprise: on average many pores in walls separating adjacent cavities; and six pores. The average interconnecting pore diameter is at least 0.5 microns or 20% or less than the average cavity diameter. The ratio of cavity diameter to pore diameter is 7:1. The cavity size is 1-50 microns in diameter. The monomer comprises a styrene-based monomer. The monomer is present in the oil phase at a concentration of 4-90 wt.%. The crosslinking agent is divinylbenzenic compound, a di- or triacrylic compound, or a triallyl isocyanurate. The crosslinking agent is present in the oil phase at a concentration of 1-89 wt.%. The emulsifier comprises an agent comprising sorbitan fatty acid ester, polyglycerol fatty acid ester, or polyoxyethylene fatty acid or ester. The emulsifier is present in the oil phase at a concentration of 3-50 wt.%. The oil phase further comprises: an oil-soluble polymerization initiator, and no polymerization initiator is present in the aqueous discontinuous phase; and porogen. The oil-soluble initiator is azoisobisbutyronitrile, benzoyl peroxide, lauroyl peroxide, or Vazo (RTM: Free radical initiators). The oil-soluble polymerization initiator is present in the oil phase at a concentration of up to 5 wt.%. The aqueous discontinuous phase consists essentially of water. The modified particle is functionalized and the degree of functionalization is greater than 50%. The different particles or groups of particles are differ in color, where the color indicated the identity of a composition within that particle or group of particles. Preferred Process: (I) is washed of residual material without first grinding (I) into smaller pieces. (I) is formed from a mixture of monofunctional monomers or polyfunctional crosslinking agents. The residual components are washed from (I) without grinding (I). ACTIVITY - Vulnerary.    MECHANISM OF ACTION - None given.    EXAMPLE - Styrene-based monomer (24 g), divinylbenzene (28 g), Span 80 (RTM: Sorbitan mono-oleate) (8 g), azoisobisbutyronitrile (0.8 g), and dodecane (35.5 g) were added and stirred at room temperature to give continuous phase. Potassium persulfate (0.78 g) was added to distilled water (840 ml) to give aqueous discontinuous phase. The continuous phase was stirred at approximately 1400 rpm, and then added the aqueous discontinuous phase to the continuous phase at a flow rate of 20 ml/minute. The combined phases were stirred at 1400 rpm for approximately 5-10 minutes to form a stable high internal phase emulsions (HIPE). The emulsion was transferred into a tray containing cavities of a predetermined size and shape. A syringe (100 ml) was filled with the HIPE and injected in the desired tray cavities in a sufficient amount for the desired final volume. The tray was then sealed and placed into an oven at a temperature of 50-55 degrees C for 4 hrs and then increased to 60-65 degrees C overnight. After polymerization and curing, the particles were washed with water, methanol and acetone to completely remove the un-polymerized monomer, initiator residue and surfactant. The particles were allowed to air-dry overnight.