TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: In the method above, the IDS is encoded by a coding sequence for a 2-C-methyl-D-erythritol 4-phosphate pathway gene (LytB gene), where gene comprises fully defined 2035 bp (SEQ ID NO. 1) given in the specification. The algal cell is derived from Dunaliella salina or Dunaliella bardawil. The polynucleotide sequence is genetically engineered to include an additional regulatory sequence, and where the additional regulatory sequence results in the increase in expression of the polynucleotide sequence that encodes IDS in the cell. The additional regulatory sequence comprises a promoter, where the promoter is selected from hydrogenase promoters, Cytochrome C 6 (Cyc6) promoter, Nia1 promoter, CabII-1 promoter, Ca1 promoter, Ca2 promoter, coprogen oxidase promoter, algal ribulose bisphosphate carboxylase small subunit gene (SSU) promoter, algal pyruvate kinase promoter, arylsulfatase promoter, aminoglycoside 3'-phosphotransferase gene (aphVIII) promoter, atpA promoter, and RbcS2 promoter. Preferably, the additional regulatory sequence comprises an expression enhancer, where the expression enhancer is selected from EE-I (agattttcaccggttggaaggaggt (SEQ ID NO: not defined)), EE-2 (cgacttacgaa (SEQ ID NO: not defined)), and gcc (SEQ ID NO: not defined)-box enhancer element. The polynucleotide sequence is genetically engineered to include an additional polynucleotide sequence that encodes IDS. In increasing production level of carotenoids, the PDS is encoded by a coding sequence for a phytoene desaturase-encoding gene (crtI) gene, where the gene comprises fully defined 1753 bp (SEQ ID NO. 2) given in the specification. The polynucleotide sequence is genetically engineered to include an additional regulatory sequence, and where the additional regulatory sequence results in the increase in expression of a polynucleotide sequence that encodes PDS in the cell. Additionally, the polynucleotide sequence is genetically engineered to include an additional polynucleotide sequence that encodes PDS. ACTIVITY - Antimalarial; Cytostatic. No biological data given.    MECHANISM OF ACTION - None given.    SPECIFIC SEQUENCES - Specifically claimed are LytB gene comprising 2035 bp (SEQ ID NO. 1); and crtI gene comprising 1753 bp (SEQ ID NO. 2). All sequences are fully defined in the specification.    EXAMPLE - No suitable example given.