TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: In producing fermentation product from lignocellulose-containing material, the distiller's grain is selected from distiller's dried grains, distiller's dried grain with solubles, and wet distillers'grain. The thermo treatment of distiller's grains is carried out at above 100 degrees C for 1 minute to 1 hour. The hydrolysis in step (c) and fermentation in step (d) is carried out as hybrid hydrolysis and fermentation steps or simultaneous hydrolysis and fermentation steps. The lignocellulose-containing material originates from materials selected from corn fiber, rice straw, wheat straw, pine wood, wood chips, bagasse, paper or pulp processing waste, corn stover, corn cobs, hardwood, softwood, cereal straw, switch grass, miscanthus, rice hulls, municipal solid waste, industrial organic waste, office paper, or mixtures. The lignocellulose-containing material is chemically, mechanically or biologically pre-treated in step (a). The pre-treated lignocellulose-containing material is unwashed or washed, or a combination of washed and unwashed pretreated lignocellulose-containing material, or is detoxified pre-treated lignocellulose-containing material. The pre-treated lignocellulose-containing constitutes from above 5 to 90 wt. %, of the total solids (TS) in the slurry in step (b). The distiller's grain constitutes from above 0-40 wt% of the pre-treated lignocellulose-containing material. The cellulolytic enzymes used for hydrolysis of the pre-treated material includes one or more cellulases. The cellulolytic enzyme(s) used for hydrolysis is a cellulolytic preparation derived from a strain of Trichoderma, a strain of the genus Humicola, or a strain of the genus Chrysosporium. One or more beta-glucosidases are present during hydrolysis, fermentation, hybrid hydrolysis and fermentation (HHF), or simultaneous hydrolysis and fermentation (SSF). The beta glucosidase is derived from a strain of Aspergillus, a strain of Trichoderma, a strain of genus Humicola, or a strain of Chrysosporium. One or more polypeptides having cellulolytic enhancing activity are present during hydrolysis, fermentation, HHF, or SSF. The pre-treated lignocellulose-containing constitutes from above 5 to 90 wt. %, of the TS in the slurry in step (b). It further comprises subjecting more hemicellulolytic enzymes during hydrolysis, fermentation, HHF, or SSF. The enzymes used for hydrolysis include a cellulolytic composition comprising a GH61A polypeptide disclosed in WO2005/074656 having cellulolytic enhancing activity; a beta-glucosidase fusion protein disclosed in WO2008/057637, and cellulolytic enzymes preparation derived from T. reesei. The fermenting organism is a C6 or C5 fermenting organism. The fermenting organism is a yeast. The fermentation product is an alcohol. EXAMPLE - No suitable example given.