TECHNOLOGY FOCUS - AGRICULTURE - Preferred Components: The non-antibiotic herbicide is a 1,2,4-triazol pyrimidine, aminotriazole amitrole, isoxazolidinone, isoxazole, diketonitrile, triketone, pyrazolinate, norflurazon, bipyridylium, aryloxyphenoxy propionate, cyclohexandione oxime, para-nitrodiphenylether, oxadiazole, N-phenyl imide, halogenated hydrobenzonitrile or urea herbicide. In the method (M1), the herbicide is glyphosate, sulfonylurea, imidazolinone, 1,2,4-triazol pyrimidine, phosphinothricin, aminotriazole amitrole, isoxa/olidinones, isoxazole, diketonitrile, triketone, pyrazolinate, norflurazon, bipyridylium, para-nitrodiphenylether, oxadiazole, aryloxyphenoxy propionate, cyclobexandione oxime, triazine, diuron, 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU), chlorsulfuron, imazaquin, N-phenyl imide, phenol herbicide, halogenated hydrobenzonitrile or urea herbicide (preferably glyphosate).    TECHNOLOGY FOCUS - BIOLOGY - Preferred Components: The alga is a eukaryotic alga or prokaryotic alga. The herbicide is glyphosate. In the method (M2), the alga is green alga or microalga. The green alga is a Chlorophycean, Chlamydomonas, Scenedesmus, Chlorella or Nannochlorpis. The Chlamydomonas is Chlamydomonas reinhardtii (preferably Chlamydomonas reinhardtii 137c). The glyphosate resistant eukaryotic alga is a microalga. The microalga is a Chlamydomonas species, Volvacales species, Dunaliella species, Scenedesmus species, Chlorella species, or Hematococcus species. The prokaryotic alga is a cyanobacter (preferably selected from Synechococcus species, Synechocystis species, Athrospira species, Anacytis species, Anabaena species, Nostoc species, Spirulina species or Fremyella species). The glyphosate resistant eukaryotic alga, non-antibiotic herbicide resistant eukaryotic alga is a non-chlorophyll c-containing eukaryotic alga, green alga or microalga. The glyphosate resistant non-chlorophyll c-containing eukaryotic alga, herbicide resistant non-chlorophyll c-containing eukaryotic alga, herbicide resistant eukaryotic alga, is alga, green alga or microalga. The non chlorophyll c-containing herbicide resistant alga is microalga, cyano bacterium, Synechococcus species, Anacytis species, Anabaena species, Nostoc species, Spirulina species or Fremyella species, eukaryotic alga, Chlamydomonas species, Volvacales species, Dunaliella species, Scenedesmus species, Chlorella species or Hematococcus species. In the prokaryotic alga, the alga is Synechococcus species, Anacytis species, Anabaena species, Nostoc species, Spirulina species or Fremyella species.    TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Components: The nucleic acid sequence encoding the protein is codon biased to reflect the codon bias of the nuclear genome of the alga; codon biased to reflect the codon bias of the nuclear genome of Chlamydomonas reinhardtii or codon biased to reflect the codon bias of the chloroplast genome of the alga. The polynucleotide (p2) is a heterologous polynucleotide, homologous polynucleotide or homologous mutant polynucleotide. The polynucleotide (p2) further comprises a promoter operably linked to the sequence encoding the protein; promoter for expression in the nucleus of Chlamydomonas reinhardtii; rbcS promoter, LHCP promoter or nitrate reductase promoter; or chloroplast transit peptide-encoding sequence. In the herbicide resistant alga, the protein is a homologous 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), homologous mutant (EPSPS) or heterologous (EPSPS); the polynucleotide (p1) comprises the nucleotide sequences (n1), nucleotide sequence homologous to the nucleotide sequences (n1) or the nucleotide sequence of the nucleotide sequences (n1) comprising at least one mutation or the protein comprises the amino acid sequences (a1), amino acid sequence homologous to the amino acid sequences (a1) or the ammo acid sequence of the amino acid sequences (a1) comprising at least one mutation. The herbicide resistant alga is glyphosate resistant eukaryotic alga comprising a recombinant polynucleotide integrated into the nuclear genome or chloroplast genome, where the recombinant polynucleotide comprises a sequence encoding EPSPS that confers glyphosate resistance to the alga; glyphosate resistant prokaryotic alga comprising a recombinant polynucleotide integrated into the genome of the alga, where the recombinant polynucleotide comprises a sequence encoding (EPSPS) that confers glyphosate resistance to the alga; a glyphosate resistant eukaryotic alga comprising a heterologous polynucleotide integrated into the chloroplast genome, where the heterologous polynucleotide comprises a sequence that encodes glyphosate oxidoreductase (GOX), glyphosate acetyl transferase (GAT), or a Class II EPSP synthase; non-antibiotic herbicide resistant eukaryotic alga comprising a polynucleotide integrated into the chloroplast genome, where the polynucleotide comprises a sequence encoding a heterologous protein whose wild-type form is not encoded by the chloroplast genome, where the protein confers resistance to a non-antibiotic herbicide that does not inhibit amino acid synthesis; a glyphosate resistant non-chlorophyll c-containing eukaryotic alga comprising a heterologous polynucleotide integrated into the nuclear genome, where the heterologous polynucleotide comprises a sequence that encodes a protein that confers resistance to glyphosate; a herbicide resistant non-chlorophyll c-containing eukaryotic alga comprising a heterologous polynucleotide integrated into the nuclear genome, where the heterologous polynucleotide comprises a sequence that encodes a protein that confers herbicide resistance to the alga; a herbicide resistant eukaryotic alga comprising at least two polynucleotide sequences encoding proteins that confer resistance to herbicides, where each of the proteins confers resistance to a different herbicide; a non chlorophyll c-containing herbicide resistant alga comprising a polynucleotide encoding a protein that confers resistance to a herbicide and heterologous polynucleotide encoding a protein that does not confer resistance to a herbicide, where the protein that does not confer resistance to a herbicide is an industrial enzyme, protein that participates in or promotes the synthesis of at least one nutritional, therapeutic, commercial, or fuel biomolecule, or protein that facilitates the isolation of at least one nutritional, therapeutic, commercial, or fuel biomolecule; eukaryotic alga comprising a polynucleotide that comprises a sequence encoding Bt toxin integrated into the chloroplast or nuclear genome; prokaryotic alga comprising a polynulcleotide that comprises a heterologous sequence. The recombinant polynucleotide encodes a homologous EPSPS. In the glyphosate resistant eukaryotic alga, the recombinant polynucleotide encodes a homologous EPSPS, or heterologous EPSPS protein. The sequence encoding the EPSPS is codon biased to reflect the codon bias of the nuclear genome of the alga; is operably linked to a promoter that functions in the nucleus of the alga; or is operably linked to a 5' or 3' untranslated region (UTR) that functions in the nucleus of the alga. In the glyphosate resistant eukaryotic alga, the promoter that functions in the nucleus of the alga comprises a 16SrRNA promoter, rbcL promoter, atpA promoter, psaA promoter, psbA promoter or psbD promoter. In the glyphosate resistant eukaryotic alga, the recombinant polynucleotide further comprises a transcriptional regulatory sequence for expression of the polynucleotide in the nucleus of the alga, where the alga is a non-chlorophyll c-containing eukaryotic alga or green alga. In the glyphosate resistant eukaryotic alga, the sequence encoding a homologous mutant EPSPS encodes alanine at the amino acid position corresponding to amino acid 96 and/or threonine at the amino acid position corresponding to amino acid 183, of the Escherichia coli EPSPS (Genbank Accession No. A7ZYL1; GI: 166988249) (SEQ ID NO: 69) (SEQ ID NO: not defined); the recombinant polynucleotide encodes a heterologous EPSPS protein; the sequence encoding the EPSPS is codon biased to reflect the codon bias of the chloroplast genome of the alga; the sequence encoding the EPSPS is operably linked to a promoter that functions in the chloroplast of the alga; the recombinant polynucleotide further comprises a transcriptional regulatory sequence for expression of the polynucleotide in the chloroplast of the alga. The glyphosate resistant eukaryotic alga is non-chlorophyll c-containing eukaryotic alga or green alga. The recombinant polynucleotide encodes a homologous mutant EPSPS; heterologous EPSPS protein. The sequence encoding the EPSPS is codon biased to reflect the codon bias of the genome of the alga; the sequence encoding the EPSPS operably linked to a promoter (preferably comprising 16SrRNA promoter, rbcL promoter, atpA promoter, psaA promoter, psbA promoter, or psbD promoter); is operably linked to a 5' UTR or 3' UTR. The sequence that encodes (GOX), (GAT), or Class II EPSP synthase, or the sequence encoding the heterologous protein in the non-antibiotic herbicide resistant eukaryotic alga is codon biased to reflect the codon bias of the chloroplast genome of the alga; is operably linked to the promoter that functions in the chloroplast of the alga; is operably linked to a 5' or 3' UTR that functions in the chloroplast of the alga. In the non-antibiotic herbicide resistant eukaryotic alga, the sequence encoding the heterologous protein encodes glutathione reductase, superoxide dismutase (SOD), acetohydroxy acid synthase (AHAS), bromoxynil nitrilase, hydroxyphenylpyruvate dioxygenase (HPPD), isoprenyl pyrophosphate isomerase, prenyl transferase, lycopene cyclase, phytoene desaturase, acetyl coenzyme A (CoA) carboxylase (ACCase), or cytochrome P450-nicotinamide adenine dinucleotide (NADH)-cytochrome P450 oxidoreductase. In the glyphosate resistant non-chlorophyll c-containing eukaryotic alga, the protein is EPSPS, (GOX) or (GAT), homologous EPSPS or homologous mutant EPSPS, heterologous EPSPS; the sequence that encodes the protein is codon biased to reflect the codon bias of the nuclear genome of the alga, is operably linked to a promoter that functions in the nucleus of the alga (preferably rbcS promoter, light-harvesting chlorophyll a/b binding protein (LHCP) promoter, or nitrate reductase promoter), is operably linked to a 5' or 3' UTR that functions in the nucleus of the alga. In the herbicide resistant non-chlorophyll c-containing eukaryotic alga, the sequence that encodes the protein is codon biased to reflect the codon bias of the nuclear genome of the alga, is operably linked to a heterologous promoter, is operably linked to a 5' or 3' UTR that functions in the nucleus of the alga; the heterologous polynucleotide further comprises genomic sequences flanking the sequence that encodes the protein, where the genomic sequences are homologous to sequences of the genome of the non-chlorophyll c-containing eukaryotic alga. In the herbicide resistant non-chlorophyll c-containing eukaryotic alga, the protein is EPSPS, (GOX), (GAT), phosphinothricin acteyl transferase (PAT), glutathione reductase, superoxide dismutase (SOD), acetolactate synthase (ALS), acetohydroxy acid synthase (AHAS), hydroxy phenylpyruvate dioxygenase (HPPD), bromoxynil nitrilase, isoprenyl pyrophosphate isomerase, prenyl transferase, lycopene cyclase, phytoene desaturase, acetyl coenzyme A (CoA) carboxylase (ACCase), or cytochrome P450-NADH-cytochrome P450 oxidoreductase (preferably (EPSPS), (GOX) or (GAT), especially (EPSPS)); the protein confers resistance to a non-antibiotic herbicide; the protein confers resistance to glyphosate. In the herbicide resistant eukaryotic alga, the polynucleotide sequences is a homologous polynucleotide sequence, homologous mutant polynucleotide sequence, or heterologous polynucleotide sequence; the polynucleotide sequences are incorporated, into the chloroplast genome of the alga. The polynucleotide sequence that is incorporated into the chloroplast or nuclear genome comprises a protein encoding sequence that is codon biased to reflect the codon bias of the chloroplast genome or nuclear genome of the alga. In the non chlorophyll c-containing herbicide resistant alga, the protein that does not confer resistance to a herbicide is an industrial enzyme, a protein that participates in or promotes the synthesis of at least one nutritional, therapeutic, commercial, or fuel biomolecule, or is a protein that facilitates the isolation of the nutritional, therapeutic, commercial, or fuel biomolecule; the polynucleotide encoding a protein that confers resistance to a herbicide is a heterologous polynucleotide, homologous polynucleotide or homologous mutant polynucleotide. In the non chlorophyll c-containing herbicide resistant alga, the polynucleotide encoding a protein that confers resistance to a herbicide is integrated into the nuclear genome or chloroplast genome; the heterologous polynucleotide encoding a protein that does not confer resistance to a herbicide is integrated into the nuclear genome; the heterologous polynucleotide encoding a protein that docs not confer resistance to a herbicide is integrated into the chloroplast genome. The non chlorophyll c-containing herbicide resistant alga comprises at least two polynucleotides encoding proteins that confer resistance to herbicides, where each of the proteins confers resistance to a different herbicide; at least two heterologous polynucleotides encoding proteins that do not confer resistance to a herbicide, where each of the proteins that do not confer herbicide resistance is a protein that participates in or promotes the synthesis of at least one nutritional, therapeutic, commercial, or fuel biomolecule, or is a protein that facilitates the isolation of at least one nutritional, therapeutic, commercial, or fuel biomolecule. The polynucleotides or heterologous polynucleotides are integrated into the chloroplast or nuclear genome; operably linked to a regulatable promoter. The regulatable promoter can be induced or repressed by at least one compound (preferably nitrate, sulfate, an amino acid, vitamin, sugar, nucleotide or nucleoside, antibiotic, or a hormone) added to the growth media of the alga. In the method (M1), the herbicide resistant alga is used to inoculate media or a body of water that includes at least one herbicide (preferably non-antibiotic herbicide). In the method (M1), the sequence conferring herbicide resistance encodes (EPSPS). In the method (M1), the alga is a eukaryotic alga or cyanobacterium; the polynucleotide comprising a sequence conferring herbicide tolerance is transformed into the algal chloroplast genome. In the method (M2) and (M3), the herbicide is glyphosate. The biomass-degrading enzyme is chlorophyllase. The polynucleotide that comprises a sequence encoding Bt toxin is a cry gene. The sequence encoding Bt toxin is codon biased to reflect the codon bias of the chloroplast genome of the alga; is operably linked to a promoter that functions in the chloroplast of the alga; or is operably linked to a 5' or 3' UTR that functions in the chloroplast of the alga. The promoter that functions in the chloroplast of the alga is a 16SrRNA promoter, rbcL promoter, atpA promoter, psaA promoter, psbA promoter or psbD promoter. The eukaryotic alga and prokaryotic alga further comprises a polynucleotide that encodes a protein that confers resistance to a herbicide. In the isolated polynucleotide (p3), the protein encoding sequence is codon biased to reflect the codon bias of the nuclear genome of Chlamydomonas reinhardtii. The isolated polynucleotide (p3) further comprises a promoter active in the nuclear genome of the alga; a promoter for expression in the nucleus of Chlamydomonas reinhardtii or a chloroplast transit peptide-encoding sequence. The promoter comprises a rbcS promoter, LHCP promoter or nitrate reductase promoter. Preferred Method: The method (M1) further involves: transforming the alga with an additional polynucleotide comprising a sequence conferring resistance to a different herbicide, where growing the alga in the presence of the herbicide involves growing the alga in the presence of the herbicide and the different herbicide; transforming the alga with a polynucleotide encoding a therapeutic protein or an industrial enzyme; transforming the alga with a polynucleotide that increases production of at least one fuel biomolecule; transforming the alga with a polynucleotide encoding a flocculation moiety or with a polynucleotide that promotes increased expression of a naturally occurring flocculation moiety or dewatering the alga by flocculating the alga; providing carbon to the alga; removing nitrogen from chlorophyll of the alga. The growing the alga in the presence of the herbicide step involves: growing the alga in a liquid medium that comprises at least one nutrient and at least one herbicide. In the method (M1), the alga is grown in an open pond; at least one of the biomolecules is a therapeutic protein or an industrial enzyme.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The fuel biomolecule comprises a lipid, fatty acid, hydrocarbon, carbohydrate, cellulose, glycerol or alcohol. The biomolecule is a fuel biomolecule. The carbon is CO2, flue gas or acetate.    TECHNOLOGY FOCUS - PHARMACEUTICALS - Preferred Components: The nutritional biomolecule comprises a lipid, carotenoid, fatty acid, vitamin, cofactor, nucleotide, amino acid, peptide, or protein. The therapeutic biomolecule comprises a vitamin, cofactor, amino acid, peptide, hormone, or growth factor. The commercial biomolecule comprises a lubricant, perfume, pigment, coloring agent, flavoring agent, enzyme, adhesive, thickener, solubiiizer, stabilizer, surfactant or coating. EXAMPLE - No suitable example given.