NOVELTY - Preparing halogenated styrene compounds (VIII), comprises reacting acetophenone compound (VII) with methylenating agent, where methylenating agent is e.g. dimethyltitanocene, diphenylmethylphosphine oxide, dimethoxymethylphosphine sulfide, pentamethylphosphonic diamide, dimethyl sulfoxide, trimethylsilyl(phenylthio)methane, titanium tetrachloride and diiodomethane or dibromomethane, methylenetriphenylphosphine, trimethylsulfonium iodide, dichloro(cyclopentadienyl)zirconium and diiodomethane or dibromomethane dimethyl methanephosphonate and methanesulfonyl chloride.    USE - The process is useful for preparing halogenated styrene compounds (VIII), which are used as precursor in the synthesis of substituted isoxazoline compounds (I) (all claimed), where (I) are used for agriculture and animal health purposes.    ADVANTAGE - The process: utilizes readily accessible and less toxic starting materials and reagents, which makes the process less expensive, safe and less time consuming than the conventional processes; reduces steps requiring less energy, hence environment friendly and easy to access and perform; provides improved yield and improved purity, which eliminate further purification steps; and eliminates the use of water as a solvent, which facilitates recycling purposes and avoid the production of waste water.    DETAILED DESCRIPTION - Preparing halogenated styrene compounds of formula (VIII) comprises reacting acetophenone compound of formula (VII) with a methylenating agent, where methylenating agent is dimethyltitanocene, diphenylmethylphosphine oxide, dimethoxymethylphosphine sulfide, pentamethylphosphonic diamide, dimethyl sulfoxide, (trialkylstannyl)(trimethylsilyl)methane, trimethylsilyl(phenylthio)methane, titanium tetrachloride and diiodomethane or dibromomethane, dichlorotitanocene and aluminum trimethyl, methylenetriphenylphosphine, trimethylsulfonium iodide, dichloro(cyclopentadienyl)zirconium and diiodomethane or dibromomethane dimethyl methanephosphonate, methanesulfonyl chloride, (chloromethyl)trimethylsilylane, diazomethyltrimethyl silane, Nysted's reagent or their precursors.    R2, R4 = H, halo or CF3;    R3 = H, F, Cl, Br or CN; and    R5 = H, F, Cl or CF3.