NOVELTY - Preparation of controllable slow-release starch derivative with glycopenia response comprises uniformly mixing starch with micronized insoluble calcium salt; adding and dispersing the mixture in natural high molecular weight polymer aqueous solution; obtaining aqueous phase dispersing agent; adding uniformly mixed aqueous phase dispersing agent to oil phase, which is edible vegetable oil; stirring the mixture; dripping glacial acetic acid solution; regulating pH; solidifying; obtaining solid microsphere; filtering; washing the microsphere with deionized water; and drying.    USE - The method is for preparation of controllable slow-release starch derivative with glycopenia response. The controllable slow-release starch derivative is used as functional material additive and slowly digestible hypoglycemia food; and as stable and targeted slow-release carrier material of functional factor such as probiotics, active polypeptide, protein, oil fat, and vitamin. (all claimed)    ADVANTAGE - The temperature-resistant slowly digestible starch (SDS) in the starch derivative is improved by greater than or equal to 15% compared with that in the original starch, which is changed within 3% when steamed at high pressure. The starch derivative has glycemic index that is lower than 55%.    DETAILED DESCRIPTION - Preparation of controllable slow-release starch derivative with glycopenia response using industrial natural high molecular weight polymer by microcapsule embedding method, comprises: (A) uniformly mixing 10-500 g starch with 1-20 g micronized insoluble calcium salt; adding and dispersing the mixture in 1 L 0.1-10% natural high molecular weight polymer aqueous solution; and obtaining aqueous phase dispersing agent, where natural high molecular weight polymer is carrageenan or sodium alginate and chitosan at 0.5:1-10:1 ratio; (B) adding uniformly mixed aqueous phase dispersing agent to oil phase, which is edible vegetable oil containing 0.5-5% Span (RTM: sorbitan fatty acid ester), where volume ratio of water and oil is 1:1-1:10; and stirring the mixture for 5-20 minutes at 100-2000 revolutions/minute; (C) dripping glacial acetic acid solution; regulating pH at 4.0-6.5; solidifying the mixture for 1-12 hours at 15-30 degrees C; and obtaining 10-150 mu m solid microsphere; and (D) filtering and collecting microsphere; washing the microsphere with deionized water; drying for 2-12 hours with hot air at 30-50 degrees C; and obtaining controllable slow-release starch derivative.