NOVELTY - Coating comprises micro and/or nano materials deposited on surface.    USE - Coating for device, preferably medical device chosen from implant which is delivered into human or animal for inhibiting biofilm formation and microbial colonization, preventing oxidation, promoting bone formation, decreasing toxicity, treating or preventing infection, promoting cell adhesion, cell proliferation and binding with biological or non-biological system, increasing or decreasing cell function, delivering drug and/or bioactive agent, or ensuring better integration of material into the host tissue with an agent or surface treatment. The agent is chosen from triclosan, iodine, silver, phenol, chloride compounds, fluoride compounds, iodine, quaternary ammonium compounds, chlorhexidine, antibiotic and antifungal agent. The medical device is chosen from orthopedic implant, dental implant, veterinary prosthetic device, graft, needle, bone material, contact lens, catheter, defibrillator, pacemaker, ear tube, endotracheal tube, stent, shunt, scaffold, tissue engineering matrix, breast implant, allograft hard tissue, allograft soft tissue, xenograft hard tissue, xenograft soft tissue, polymeric mesh and ceramic mesh. The orthopedic implant is chosen from hip implant, knee implant, shoulder implant, plate, pin, screw, wire and rod. The dental implant is chosen from abutment, healing screw and cover screw. The medical device comprises plasmids, genes, nucleic acids or DNA or RNA virus. The biofilm is chosen from bacterial, fungal and protozoan biofilm. The surface treatment is chosen from plasma treatment and ion or electron treatment (claimed).    ADVANTAGE - The coating induces formation of surface charges that enhance binding of bioactive agents, growth factors and drugs and increases hydrophilic nature of the surface. The coating is biodegradable and biocompatible.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following:    (1) implant comprising titanium, where zirconium coats at least one surface of implant;    (2) method for coating a portion or surface of implant with zirconia, involves depositing zirconia on the surface by ion beam deposition, electron beam deposition, pulsed laser deposition, thermal sputtering and deposition, radiofrequency (RF) sputtering, laser etching, glancing angle deposition, electrospray, chemical vapor deposition, physical vapor deposition and molecular epitaxy, where the deposition produces crystalline film;    (3) method of sterilizing a nanocomposite coated medical device, involves exposing the device to ethylene oxide or gamma radiation;    (4) package comprising a nanocomposite coated medical device, where the device is sealed in an airtight or vacuum packed container;    (5) nanoparticle comprising a core made of one nanoparticle material and at least one layer surrounding the core, where the layer comprises another nanoparticle material core;    (6) method for coating a surface of orthodontic wire, removable partial denture clasp or connector used in dentistry, involves depositing zirconia on the wire, removable partial denture clasp or connector by the above-mentioned method; and    (7) method for producing orthodontic wire, removable partial denture clasp or connector, involves depositing zirconia by pulsed laser deposition on the wire, removable partial denture clasp or connector.