TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: In extracting bezafibrate high efficient degrading strain, the inorganic salt culture medium of the step (a) is 4.35 g/L of Dipotassium phosphate (K2HPO4), 1.7 g/L of potassium biphosphate (KH2PO4), 2.1 g/L of ammonium chloride (NH4Cl), 0.2 g/L of magnesium sulfate (MgSO4), 0.05 g/L of manganese sulfate (MnSO4), 0.01 g/L of ferrous sulfate (FeSO4).7H2O, 0.03 g/L of calcium chloride (CaCl2).2H2O and 1000 mL of distilled water, where the pH is 6.8-7.0. The gradient pressure acclimatization method of the step (a) comprise orderly adding bezafibrate to the inorganic salt culture medium so that the concentration is 10, 15, 20, 25, 30, 35 mg/L, the interval time for charging the concentration is 10 days; the acclimatization is performed at 30-35 degrees C with a surging speed ratio of 160 revolutions per minute. The gradient dilution means 10-1 to 10-10 of gradient dilution. The solid culture medium of the step (b) comprises adding 17 g/L of agar powder to the enrichment culture medium, heating and melting it, cooling it to form the culture medium, where the enrichment culture medium comprises 3.0 g/L of beef extract, 10.0 g/L of peptone, 5.0 g/L of sodium chloride (NaCl) and 1000 mL of distilled water, where the pH is 7.0-7.2; the inclined culture medium comprises heating and melting the solid culture medium, providing the test tube, pouring 5 ml of solid culture medium into the test tube, putting the test tube end on the glass rod so that the inclined surface is formed in the tube culture medium. The enrichment culture of the step (b) comprises inoculating the strain on the solid culture medium, culturing it for 48 hours at 30 degrees C, selecting the clear single strain, numbering it, drawing line on the solid culture medium, inversely putting the culture instrument on the culture case for 48 hours at 30 degrees C, observing the strain shape by electron microscope, repeating it for 2-4 times to make sure the obtaining of the pure single strain. The bezafibrate high efficient degrading strain is measured and analyzed by 16S rDNA so that the strain is deformed pseudomonas named Pseudomonas plecoglossicida.B-3; the length of the strain is 0.2-0.5 microns; the diameter of the strain is 0.5-2.5 mm and it is in the form of circular; the edge is regular and the surface is convex and has luster; it is milk-white and semi-transparent; it has not spurt, capsule and need oxygen; it has low nutrition rest and can produce water-soluble pigment; the gram stain is negative; the optimal growth condition pH is 6.8-7.6, the temperature is 30-35 degrees C; the table concentrator surging speed ratio is 160 revolutions per minute.