TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preparation (Disclosed): Preparation of compound (I) involves coupling an acid chloride compound of formula (II) with an amine compound of formula (III) in the presence of an acid scavenger to form compound (I). Full Definitions:    A=-O-, -S-, -N(R7)-, -C(R8)2-, -OC(R8)2-, -SC(R8)2- or -N(R7)C(R8)2-, where the bond projecting to the left is connected to the nitrogen atom of compound (I), and the bond projecting to the right is connected to the carbon atom of compound (I);    W'=O or S;    G=5-membered heterocyclic ring (optionally substituted);    Z'=direct bond, O, C(=O), S(=O)m, CH(R12) or N(R13);    J=5- to 7-membered ring, 8- to 11-membered bicyclic ring system or 7- to 11-membered spirocyclic ring system, (all ring or ring system optionally mono to penta substituted R6), where each ring or ring system containing ring members selected from carbon atoms and up to 4 heteroatoms selected from up to 2 O, up to 2 S, up to 4 N and up to 2 Si atoms, where up to 3C ring members are selected from C(=O) and C(=S), the sulfur atom ring members selected from S(=O)s(=NR11)f and the silicon atom ring members are selected from SiR9R10;    W2=O or S;    T'a=H or 1-3C alkyl;    T'b=CR14R15R16;    X=X1-X9, where t is connected to the carbon atom with q of compound (I), the bond which is identified with u is connected to the carbon atom with r of compound (I), and the bond which is identified with v is connected to G of compound (I);    R1=H, halogen, cyano, amino, -CHO, -C(=O)OH, -C(K))NH2, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 1-6C haloalkyl, 2-6C haloalkenyl, 2-6C haloalkynyl, 3-6C cycloalkyl, 3-6C halocycloalkyl, 4-6C alkylcycloalkyl, 4-6C cycloalkylalkyl, 4-6C halocycloalkylalkyl, 3-6C cycloalkenyl, 3-6C halocycloalkenyl, 2-6C alkoxyalkyl, 2-6C alkylthioalkyl, 2-6C alkylsulfinylalkyl, 2-6C alkylsulfonylalkyl, 2-6C alkylaminoalkyl, 3-6C dialkylaminoalkyl, 2-6C haloalkylaminoalkyl, 2-6C alkylcarbonyl, 2-6C haloalkylcarbonyl, 4-6C cycloalkylcarbonyl, 2-6C alkoxycarbonyl, 4-6C cycloalkoxycarbonyl, 5-6C cycloalkylalkoxycarbonyl, 2-6C alkylaminocarbonyl, 3-6C dialkylaminocarbonyl, 1-6C alkoxy, 1-6C haloalkoxy, 3-6C cycloalkoxy, 3-6C halocycloalkoxy, 2-6C alkenyloxy, 2-6C haloalkenyloxy, 2-6C alkynyloxy, 3-6C haloalkynyloxy, 2-6C alkoxyalkoxy, 2-6C alkylcarbonyloxy, 2-6C haloalkylcarbonyloxy, 1-6C alkylthio, 1-6C haloalkylthio, 3-6C cycloalkylthio, 1-6C alkylamino, 2-6C dialkylamino, 1-6C haloalkylamino, 2-6C halodialkylamino, 3-6C cycloalkylamino, 2-6C alkylcarbonylamino, 2-6C haloalkylcarbonylamino, 1-6C alkylsulfonylamino or 1-6C haloalkylsulfonylamino;    R2=H, halogen, cyano, hydroxy, 1-3C alkyl, 1-3C haloalkyl, 1-3C alkoxy, 1-3C haloalkoxy or 1-3C alkylthio;or    R1+R2+C=3- to 7-membered ring (optionally mono to tetra substituted by halogen, cyano, 1-2C alkyl, 1-2C haloalkyl, 1-2C alkoxy or 1-2C haloalkoxy on carbon atom ring members and cyano, 1-2C alkyl and 1-2C alkoxy on nitrogen atom ring members) where ring contains carbon atoms and up to 4 heteroatoms selected from up to 2 O, up to 2 S, up to 2 N and up to 2 Si atoms, where up to 3 carbon atom ring members are selected from C(=O) and C(=S), the sulfur atom ring members are selected from S(=O)s(=NR11)f and the silicon atom ring members are selected from SiR9R10;    R3=phenyl, naphthalenyl or 5- to 6-membered heteroaromatic ring (all optionally substituted); or H, halogen, cyano, hydroxy, -CHO, 1-4C alkyl, 2-4C alkenyl, 2-4C alkynyl, 1-4C haloalkyl, 2-4C haloalkenyl, 2-4C haloalkynyl, 2-4C alkoxyalkyl, 2-4C alkylthioalkyl, 2-4C alkylsulfmylalkyl, 2-4C alkylsulfonylalkyl, 2-4C alkylcarbonyl, 2-4C haloalkylcarbonyl, 2-5C alkoxycarbonyl, 2-5C alkylaminocarbonyl, 3-5C dialkylaminocarbonyl, 1-4C alkoxy, 1-4C haloalkoxy, 1-4C alkylthio, 1-4C haloalkylthio, 1-4C alkylsulf?nyl, 1-4C haloalkylsulf?nyl, 1-4C alkylsulfonyl, 1-4C haloalkylsulfonyl, 2-4C alkylcarbonyloxy, 2-4C haloalkylcarbonyloxy, 2-5C alkoxycarbonyloxy, 2-5C alkylaminocarbonyloxy or 3-5C dialkylaminocarbonyloxy;    R4=H, 1-3C alkyl or 1-3C haloalkyl;or    R3+R4+C=3- to 6-membered saturated carbocyclic ring;    R5=halogen, cyano, hydroxy, 1-4C alkyl, 1-4C alkenyl, 1-4C haloalkyl or 1-4C alkoxy;    R6=H, halogen, cyano, hydroxy, amino, nitro, -CHO, -C(=O)OH, -C(=O)NH2, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 1-6C haloalkyl, 2-6C haloalkenyl, 2-6C haloalkynyl, 3-8C cycloalkyl, 3-8C halocycloalkyl, 4-10C alkylcycloalkyl, 4-10C cycloalkylalkyl, 6-14C cycloalkylcycloalkyl, 4-10C halocycloalkylalkyl, 5-10C alkylcycloalkylalkyl, 3-8C cycloalkenyl, 3-8C halocycloalkenyl, 2-6C alkoxyalkyl, 4-10C cycloalkoxyalkyl, 3-8C alkoxyalkoxyalkyl, 2-6C alkylthioalkyl, 2-6C alkylsulf?nylalkyl, 2-6C alkylsulfonylalkyl, 2-6C alkylaminoalkyl, 3-8C dialkylaminoalkyl, 2-6C haloalkylaminoalkyl, 4-10C cycloalkylaminoalkyl, 2-6C alkylcarbonyl, 2-6C haloalkylcarbonyl, 4-8C cycloalkylcarbonyl, 2-6C alkoxycarbonyl, 4-8C cycloalkoxycarbonyl, 5-10C cycloalkylalkoxycarbonyl, 2-6C alkylaminocarbonyl, 3-8C dialkylaminocarbonyl, 4-8C cycloalkylaminocarbonyl, 2-6C haloalkoxyalkyl, 1-6C hydroxyalkyl, 1-6C alkoxy, 1-6C haloalkoxy, 3-8C cycloalkoxy, 3-8C halocycloalkoxy, 4-10C cycloalkylalkoxy, 2-6C alkenyloxy, 2-6C haloalkenyloxy, 2-6C alkynyloxy, 2-6C haloalkynyloxy, 2-6C alkoxyalkoxy, 2-6C alkylcarbonyloxy, 2-6C haloalkylcarbonyloxy, 4-8C cycloalkylcarbonyloxy, 3-6C alkylcarbonylalkoxy, 1-6C alkylthio, 1-6C haloalkylthio, 3-8C cycloalkylthio, 1-6C alkylsulfinyl, 1-6C haloalkylsulfinyl, 1-6C alkylsulfonyl, 1-6C haloalkylsulfonyl, 3-8C cycloalkylsulfonyl, 3-10C trialkylsilyl, 1-6C alkylsulfonylamino, 1-6C haloalkylsulfonylamino, -NR17R18 or -Z2Q;    Z2=direct bond, O, C(=O), S(=O)m, CH(R12) or N(R13);    Q=phenyl, benzyl, naphthalenyl, a 5- to 6-membered heteroaromatic ring or 8- to 11-membered heteroaromatic bicyclic ring system (all optionally mono- or di-substituted by R6b on carbon and nitrogen atom ring members, or optionally mono- to penta-substituted by R6a on carbon atom ring members and selected from 1-3C alkyl, 2-3C alkylcarbonyl, 2-3C alkoxycarbonyl or 1-3C alkoxy on nitrogen atom ring members); or a 3- to 7-membered nonaromatic carbocyclic ring, a 5- to 7-membered nonaromatic heterocyclic ring or 8- to 11-membered nonaromatic bicyclic ring system, where each ring or ring system containing ring members selected from carbon atoms and up to 4 heteroatoms selected from up to 2 O, up to 2 S, up to 4 N and up to 2 Si atoms, where up to 3 carbon atom ring members are selected from C(=O) and C(=S), the sulfur atom ring members are selected from S(=O)s(=NR11)f, and the silicon atom ring members are selected from SiR9R10 (all optionally mono- or di-substituted by R6b on carbon and nitrogen atom ring members, or mono to penta substituted by R6a on carbon atom ring members and selected from 1-3C alkyl, 2-3C alkylcarbonyl, 2-3C alkoxycarbonyl and 1-3C alkoxy on nitrogen atom ring members);    R6a=halogen, hydroxy, amino, cyano, nitro, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 3-6C cycloalkyl, 4-10C cycloalkylalkyl, 4-10C alkylcycloalkyl, 5-10C alkylcycloalkylalkyl, 6-14C cycloalkylcycloalkyl, 1-6C haloalkyl, 2-6C haloalkenyl, 2-6C haloalkynyl, 3-6C halocycloalkyl, 1-4C alkoxy, 1-4C haloalkoxy, 1-4C alkylthio, 1-4C halo alkylthio, 1-4C alkylsulfmyl, 1-4C alkylsulfonyl, 1-4C haloalkylsulfinyl, 1-4C haloalkylsulfonyl, 1-4C alkylamino, 2-6C dialkylamino, 3-6C cycloalkylamino, 2-4C alkoxyalkyl, 1-4C hydroxyalkyl, 2-4C alkylcarbonyl, 2-6C alkoxycarbonyl, 2-6C alkylcarbonyloxy, 2-6C alkylcarbonylthio, 2-6C alkylaminocarbonyl, 3-8C dialkylaminocarbonyl or 3-6C trialkylsilyl;    R6+R6a=5- to 7-membered ring containing ring members selected from carbon atoms and optionally up to 3 heteroatoms selected from up to 1 O, up to 1 S and up to 1 N atom (all optionally mono- to tri-substituted by halogen, cyano, nitro, 1-2C alkyl and 1-2C alkoxy on carbon atom ring members and cyano, 1-2C alkyl and 1-2C alkoxy on nitrogen atom ring members);    R6b=phenyl (optionally mono- to tri-substituted by halogen, cyano, 1-2C alkyl, 1-2C haloalkyl, 1-2C alkoxy or 1-2C haloalkoxy); or a 5- to 6-membered heteroaromatic ring containing ring members selected from carbon atoms and up to 4 heteroatoms selected from up to 2 O, up to 2 S and up to 4 N atoms (optionally mono- to tri-substituted by halogen, cyano, 1-2C alkyl, 1-2C haloalkyl, 1-2C alkoxy or 1-2C haloalkoxy on carbon atom ring members and cyano, 1-2C alkyl and 1-2C alkoxy on nitrogen atom ring members); or 3- to 7-membered nonaromatic ring containing ring members selected from carbon atoms and up to 4 heteroatoms selected from up to 2 O, up to 2 S and up to 4 N atoms, where up to 3 carbon atom ring members are selected from C(=O) and C(=S) (optionally mono- to tri-substituted by halogen, cyano, 1-2C alkyl, 1-2C haloalkyl, 1-2C alkoxy and 1-2C haloalkoxy on carbon atom ring members and cyano, 1-2C alkyl and 1-2C alkoxy on nitrogen atom ring members);    R7=H, cyano, 1-4C alkyl, 1-4C haloalkyl, 2-4C alkoxyalkyl, 2-4C alkylthioalkyl, 2-4C alkylcarbonyl, 2-4C haloalkylcarbonyl, 2-4C alkoxycarbonyl, 2-4C alkylaminocarbonyl, 3-5C dialkylaminocarbonyl, 1-4C alkylsulfonyl or 1-4C haloalkylsulfonyl;or    R2+R7=5- to 7-membered partially unsaturated ring containing ring members, in addition to the linking atoms, selected from carbon atoms and up to 3 heteroatoms selected from up to 1 O, up to 1 S and up to 1 N atom (optionally mono- to tri-substituted by halogen, cyano, nitro, 1-2C alkyl, 1-2C haloalkyl, 1-2C alkoxy or 1-2C haloalkoxy on carbon atom ring members and cyano, 1-2C alkyl and 1-2C alkoxy on nitrogen atom ring members);    R8=H, 1-3C alkyl or 1-3C haloalkyl;    R9 and R10=1-5C alkyl, 2-5C alkenyl, 2-5C alkynyl, 3-5C cycloalkyl, 3-6C halocycloalkyl, 4-10C cycloalkylalkyl, 4-7C alkylcycloalkyl, 5-7C alkylcycloalkylalkyl, 1-5C haloalkyl, 1-5C alkoxy or 1-5C haloalkoxy;    R11=H, cyano, 1-6C alkyl, 1-6C haloalkyl, 3-8C cycloalkyl, 3-8C halocycloalkyl, 1-6C alkoxy, 1-6C haloalkoxy, 1-6C alkylamino, 2-8C dialkylamino, 1-6C haloalkylamino or phenyl;    R12=H, 1-4C alkyl or 1-4C haloalkyl;    R13=H, 1-4C alkyl, 1-4C haloalkyl, 3-6C cycloalkyl, 2-4C alkylcarbonyl, 2-4C haloalkylcarbonyl, 2-4C alkoxycarbonyl or 2-4C haloalkoxycarbonyl;    R14=H or 1-4C alkyl;    R15=phenyl, benzyl, naphthalenyl or a 5- to 6-membered heteroaromatic ring (all optionally mono- to tri-substituted by R19);    R16=H, cyano, nitro, 1-6C alkyl, 2-6C alkenyl or 2-6C alkynyl;    R17=H, 1-6C alkyl, 1-6C haloalkyl, 3-8C cycloalkyl, 2-6C alkylcarbonyl, 2-6C haloalkylcarbonyl, 2-6C alkoxycarbonyl or 2-6C haloalkoxycarbonyl;    R18=1-6C alkyl, 1-6C haloalkyl, 3-8C cycloalkyl, 2-6C alkylcarbonyl, 2-6C haloalkylcarbonyl, 2-6C alkoxycarbonyl, 2-6C haloalkoxycarbonyl or -Z3Q;    R19=halogen, cyano, hydroxy, 1-3C alkyl, 1-3C haloalkyl or 1-3C alkoxy;    R16+R19=3- to 7-membered ring containing ring members selected from carbon atoms and up to 4 heteroatoms selected from up to 2 O, up to 2 S, up to 2 N and up to 2 Si atoms, where up to 2 carbon atom ring members are selected from C(=O) and C(=S), the sulfur atom ring members are selected from S(=O)s(=NR11)f, and the silicon atom ring members are selected from SiR9R10 (optionally mono- to tetra-substituted by halogen, cyano, hydroxy, 1-2C alkyl or 1-2C alkoxy on carbon atom ring members and cyano, 1-2C alkyl and 1-2C alkoxy on nitrogen atom ring members);    Z3=O, C(=O), S(=O)m or CH(R12);    m=0, 1 or 2;    n=0, 1 or 2;and    s and f=0, 1 or 2.    Provided that:    (1) when Z' is a direct bond, then J is C(=W2)NT'aT'b; and    (2) the sum of s and f is 0, 1 or 2.    The two R5 groups are taken together as 1-4C alkylene or 2-4C alkenylene to form a bridged bicyclic or fused bicyclic ring system; or two R5 groups attached to adjacent ring carbon atoms joined by a double bond are taken together as -CH=CH-CH=CH- optionally substituted with up to 3 substituents selected from halogen, cyano, hydroxy, amino, nitro, 1-4C alkyl, 1-4C haloalkyl, 1-4C alkoxy and 1-4C haloalkoxy.    ACTIVITY - Fungicide; Plant protectant. The efficacy of 2,2,2-trifluoroacetaldehyde, O-(2-(4-(4-(5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl)-2-thiazolyl)-1-piperidinyl)-2-oxoethyl)oxime (Ib) against Plasmopara viticola was tested as follows: grape seedlings were inoculated with a spore suspension of Plasmopara viticola. Then grape seedlings were sprayed with suspension of compound (Ib) and after 5 days percentage control was measured. The compound (Ib) showed 100% of Plasmopara viticola.    MECHANISM OF ACTION - None given.    ADMINISTRATION - The compound is applied by sparing at the dosage of less than 1-5000 g/hectare or 0.1-10 g/kg of seed.    SPECIFIC COMPOUNDS - 13 Compounds are specifically claimed as compound (I) e.g. propan-2-one O-(2-(4-(4-(5-(2,6-difluoro-phenyl)- 4,5-dihydro-isoxazol-3-yl)-thiazol-2-yl)- piperidin-1-yl)-2-oxo-ethyl)-oxime; 2,2,2-trifluoroacetaldehyde 2-(2-(4-(4-(5-(2,6-difluorophenyl)- 4,5-dihydro-3-isoxazolyl)-2-thiazolyl)-1-piperidinyl)-2-oxoethyl)- 2-methylhydrazone; 2-(4,5-dihydro-3-(2-(1-(2-(((2,2,2-trifluoroethylidene)amino) oxy)acetyl)-4-piperidinyl)-4-thiazolyl)-5-isoxazolyl)benzonitrile; 2,2,2-trifluoroacetaldehyde, O-(2-(4-(4- (5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl)-2- thiazolyl)-1-piperidinyl)-2-oxoethyl)oxime; 1-(4-(4-(5-(2,6-difluorophenyl)-4,5- dihydro-3-isoxazolyl)-2-thiazolyl)- 1-piperidinyl)-2-(4,5-dihydro-5-methyl-3 -(trifluoromethyl)-1H-pyrazol-1-yl)ethanone.    EXAMPLE - A mixture of 2-((2,2,2-trifluoroethylidene)amino)oxy)acetic acid (565 mg), 4-(4-(5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl)-2-thiazolyl)piperidine (1.50 g), N3-(ethylcarbodimidoyl)-N1,N1-dimethyl-1,3-propanediamine hydrochloride (633 mg), 1-hydroxybenzotriazole (40.5 mg) and triethylamine (460 mu l) in dichloromethane (8 ml) was stirred at room temperature. After 3 hours, the reaction mixture was diluted with dichloromethane, washed with water, aqueous hydrochloric acid solution, water, saturated aqueous sodium bicarbonate solution and saturated aqueous sodium chloride solution. After work-up to form 2,2,2-trifluoroacetaldehyde, O-(2-(4-(4-(5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl)-2-thiazolyl)-1-piperidinyl)-2-oxoethyl)oxime (455 mg).