NOVELTY - Producing topical scrub, comprises: providing particle material suitable for producing a customized anisotropic particle; producing many customized anisotropic particles composed of the particle material, each customized anisotropic particle having particle shape, volume and composition; and dispersing many customized anisotropic particles in a fluid material to form a dispersion, where at least a feature of the particle shape facilitates embedding at least a portion of many customized anisotropic particles into topical surface by scrubbing action.    USE - The method is useful producing topical scrub (claimed). The topical scrub comprising therapeutic customized anisotropic particles is useful for efficient localized treatment of at least one of dermal malady or sub-dermal malady.    ADVANTAGE - The method provides the topical scrub having unique combination of features in a topical material which provides a highly useful material composition and enables a process for one-time topical application of a topical scrub containing custom-shaped and custom-sized anisotropic particles that are typically bio-compatible and bio-active. The customized anisotropic particle particles facilitate embedding of the particles into topical surfaces and provides a long time release profile for a single-application treatment.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for:    (1) a multi-component composition, comprising: first material component in which customized anisotropic particles can be dispersed; and many customized anisotropic particles dispersed in the first material component, where: each customized anisotropic particle has particle shape, volume and composition; at least a feature of the particle shape facilitates embedding at least a portion of many customized anisotropic particles into a topical surface by a scrubbing action; and the customized anisotropic particles is at least 100 particles; and    (2) a system for producing topical scrub, comprising: particle production system structured to produce many customized anisotropic particles; and dispersion system arranged proximate to the particle production system to be able to receive many customized anisotropic particles and fluid material, and through which many customized anisotropic particles can be dispersed in the fluid material, where each of many customized anisotropic particles has at least a feature of a shape that facilitates embedding of at least a portion of the customized anisotropic particles into a topical surface by a scrubbing action.