NOVELTY - Making hybrid diesel fuel product involves combining vegetable oil with diesel fuel to form first mixture; hydrotreating first mixture to yield second mixture, where triglyceride components of first mixture are deoxygenated; isomerizing second mixture in presence of isomerization catalyst to yield third mixture; and isolating the hybrid diesel fuel of the third mixture to yield hybrid diesel fuel product.    USE - Method useful for making hybrid diesel fuel product (claimed).    ADVANTAGE - The method has ability to eliminate interstage removal of H2S/NH3 between hydrotreating and isomerization, thus provided by isomerization catalyst that is sulfur- and nitrogen-tolerant. The method could economically-utilizes biomass in the production of hydrotreated diesel fuels, while still maintaining a relatively low cloud point; provides a hybrid diesel product that benefits from a (partial) biomass-derived component, but without the poor low-temperature properties of conventional ester-based biodiesel.    DETAILED DESCRIPTION - Making a hybrid diesel fuel product involves combining vegetable oil with diesel fuel to form a first mixture, where the vegetable oil having not greater than 10 wt.% of the first mixture; hydrotreating the first mixture to yield a second mixture, where triglyceride components of the first mixture are deoxygenated, and where at least 95 atomic percent of the sulfur present in the first mixture is converted to H2S in the second mixture; isomerizing the second mixture in the presence of an isomerization catalyst to yield a third mixture comprising hybrid diesel fuel having a cloud point that is lower than that of the second mixture, where H2S in the second mixture has not been removed prior to isomerizing; and isolating the hybrid diesel fuel of the third mixture to yield a hybrid diesel fuel product. An INDEPENDENT CLAIM is included for a system for generating a hybrid diesel fuel product comprising a mixing unit for combining vegetable oil with diesel fuel to form a first mixture; a hydrotreating unit for hydrotreating the first mixture to yield second mixture; and an isomerization unit for isomerizing the second mixture in the presence of an isomerization catalyst to yield a third mixture.