TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Sequences: The polypeptide comprises SEQ ID NO: 2 with 1-50 conservative amino acid substitutions and a mutation in any of the following residues Asp430, Ala453, Ala460 or Gly462 to remove leucine feedback inhibition. The polypeptide comprises a sequence that is at least 80-99% identical to a sequence selected from EVEN SEQ ID NOS: 4-16 that when expressed with a LeuB, C and D is capable of converting 2-keto-3-methylvalerate to 2-keto-4-methylhexanoate. The Gly462 mutation is a Gly462Ala mutation. The polypeptide comprises SEQ ID NO: 18 with 1-50 conservative amino acid substitutions and a Val461Ala mutation and may further comprise at least one additional mutation at Met538 or Phe381. The polypeptide comprises a sequence that is at least 80-99% identical to a sequence selected from EVEN SEQ ID NOS: 18-28 and that is capable of promoting the conversion of a C6-C9 keto acid to a C5-C8 alcohol. The polynucleotide comprises a sequence that hybridizes to a sequence selected from ODD SEQ ID NOS: 1-15, where the polynucleotide encodes a polypeptide that promotes the conversion of 2-keto-3-methylvalerate to 2-keto-4-methylhexanoate. The polynucleotide encodes a polypeptide that is at least 80-99% identical to a LeuA polypeptide of EVEN SEQ ID NOS: 4-16. The polynucleotide comprises a sequence that is at least 80-99% identical to ODD SEQ ID NOS: 1-15 and encodes a polypeptide that promotes the conversion of 2-keto-3-methylvalerate to 2-keto-4-methylhexanoate. The polynucleotide is part of an operon comprising LeuBCD, where the operon converts 2-keto-3-methylvalerate to 2-keto- 4-methylhexanoate. The polynucleotide comprises a sequence that hybridizes to a sequence selected from ODD SEQ ID NOS: 17-27, where the polynucleotide encodes a polypeptide that promotes the conversion of C6-C9 keto acid to the corresponding C5-C8 alcohol. The polynucleotide encodes a polypeptide that is at least 80-99% identical to a Kivd polypeptide of EVEN SEQ ID NOS: 20-28 and which promotes the conversion of a C6-C9 keto acid to the corresponding C5-C8 alcohol. The polynucleotide comprises a sequence that is at least 80-99% identical to ODD SEQ ID NOS: 17-27 and encodes a polypeptide that promotes the conversion of a C7-C9 keto acid to a C6-C8 alcohol. Preferred Microorganism: The microorganism produces a C5-C8 alcohol. The mutant 2-isopropylmalate synthase has a larger binding pocket compared to a wild-type 2-isopropylmalate synthase. The microorganism is selected from a genus of Corynebacterium, Lactobacillus, Lactococcus, Salmonella, Enterobacter, Pseudomonas, Enterococcus, Erwinia, Pantoea, Morganella, Pectobacterium, Proteus, Serratia, Shigella, Klebsiella, Citrobacter, Saccharomyces, Dekkera, Klyveromyces, Escherichia and Pichia. The biosynthetic pathway for the production of an amino acid in the organism is modified for production of the alcohol. The microorganism comprises reduced ethanol production capability compared to a parental microorganism. The microorganism is derived from E. coli. The recombinant microorganism comprises a keto-acid decarboxylase selected from Pdc, Pdc1, Pdc5, Pdc6, Aro10, Thi3, Kivd, and KdcA, a homolog or variant of any of the foregoing, and a polypeptide having at least 60% identity to any one of these and having 2-keto-acid decarboxylase activity. The keto-acid decarboxylase is encoded by a polynucleotide having at least 60% identity to a nucleic acid selected from pdc, pdc1, pdc5, pdc6, aro10, thi3, kivd, kdcA, its homolog or variant, or its fragment, and where the polynucleotide encodes a polypeptide having 2-keto acid decarboxylase activity. The 2-keto-acid decarboxylase is encoded by a polynucleotide derived from a kivd gene, or its homolog, where the 2-keto-acid decarboxylase comprises a sequence that encodes a polypeptide of SEQ ID NO: 18 having a Val461Ala mutation. The recombinant organism comprises an alcohol dehydrogenase selected from Adh1, Adh2, Adh3, Adh4 , Adh5, Adh6, Sfa1, its homolog or variant, and a polypeptide having at least 60% identity to any one of these and having alcohol dehydrogenase activity. The alcohol dehydrogenase is encoded by a polynucleotide having at least 60% identity to a nucleic acid selected from an adh1, adh2 , adh3 , adh4 , adh5, adh6, sfa1 gene, and its homolog and where the polynucleotide encodes a protein having 2-alcohol dehydrogenase activity. The microorganism comprises a knockout of an enzyme that competes with a metabolite for production of a C5, C6, C7 or C8 alcohol. The recombinant microorganism comprises a feedback resistant ThrAasterisk. The mutant 2-isopropylmalate synthase comprises an E. coli LeuA having one or more mutations selected from Gly462Asp, Ser139Gly, His97Ala, and Asn167Ala; where the mutant 2-isopropylmalate synthase comprises a Gly462Asp/Ser139Gly/Asn167Ala triple mutant or a Gly462Asp/Ser139Gly/His97Ala/Asn167Ala quadruple mutant. SPECIFIC SEQUENCES - The evolved enzyme comprises an amino acid sequence of EVEN SEQ ID NOS: 2-28 encoded by a polynucleotide comprising a nucleotide sequence of ODD SEQ ID NOS: 1-27. Sequences not defined here may be found at ftp://ftp.wipo.int/pub/published_pct_sequences/publication.    EXAMPLE - No suitable example given.