TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Composition: The denatured methanol comprises (wt.%) fuel methanol (15-82), fatty alcohol (1.5-5), fatty ether (1.7-9.7), and methanol denaturant (0.5-1.8). The denatured gasoline comprises (wt.%) naphtha or commercial gasoline (7.8-50), condensate (1-10), 5C (1-5.5), toluene or dimethylbenzene (1-5), petroleum ether or ether (0.5-1.1), and gasoline denaturant (0.3-1.2). The methanol denaturant comprises (wt.%) methanol gasoline thermal synergistic agent (66-80) according to Patent 200910164612.3, methanol gasoline water soluble agent (17-28) according to Patent 200910164611.9, and methanol gasoline gas blocking reducing agent (3-8) according to Patent 200910160503.4. The gasoline denaturant comprises (wt.%) methanol gasoline metal corrosion inhibitor (25-40) according to Patent 200910160505.3, methanol gasoline rubber anti-swelling agent (18-28) according to Patent 200910164605.3, and methanol gasoline stabilizer (35-50) according to Patent 200910160504.9. Preferred Component: The fatty alcohol comprises 3-5C normal or isomeric carbon alcohol, preferably isopropyl alcohol or isobutyl alcohol. The fatty ether comprises methyl tert-butyl ether or ethyl tert-butyl ether. The stable high performance methanol gasoline is prepared by (A) preparing denaturant comprising preparing methanol denaturant by adding thermal synergistic agent to stirrer, adding water soluble agent, and gas blocking reducing agent while stirring, and uniformly stirring; and preparing gasoline denaturant by adding metal corrosion inhibitor to reactor, adding rubber anti-swelling agent, and stabilizer while stirring, and uniformly stirring; (B) preparation of denatured methanol by adding fuel methanol, fatty alcohol, fatty ether, and methanol denaturant to stirrer and uniformly stirring; (C) preparation of denatured gasoline by adding naphtha or commercial gasoline, condensate, 5C, toluene or dimethylbenzene, petroleum ether or ether, and gasoline denaturant to reactor; and uniformly stirring; and (D) preparation of stable high performance methanol gasoline by adding denatured methanol to denatured gasoline; and uniformly stirring.