TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: Alternatively, hydrolyzing a polysaccharide comprises: (a) contacting the polysaccharide with mesophilic hydrolytic enzymes to produce a reaction mixture, (b) incubating the reaction mixture at a temperature suitable for activity of the mesophilic hydrolytic enzymes, (c) contacting the reaction mixture with thermophilic hydrolytic enzymes, and (d) incubating the reaction mixture at a temperature suitable for activity of the thermophilic hydrolytic enzymes, where the polysaccharide is hydrolyzed by the mesophilic and thermophilic hydrolytic enzymes to produce two or more polysaccharide fragments. The temperature suitable for activity of the mesophilic hydrolytic enzymes is between about 45 degrees C and about 55 degrees C. The temperature suitable for activity of the mesophilic hydrolytic enzymes is about 50 degrees C. The temperature suitable for activity of the thermophilic hydrolytic enzymes is above 60 degrees C. The temperature suitable for activity of the thermophilic hydrolytic enzymes is above about 70 degrees C. The mesophilic or thermophilic hydrolytic enzyme is a hydrolase. The hydrolase is a glycosylase. The glycosylase is selected from the group consisting of xylanases, glucosidases, cellulases, xylosidases, mannanases, mannosidases, arabinosidases, glycoside hydrolases, dextranases, cellobiohydrolases exoglucanases, and endoglucanases. The mesophilic hydrolytic enzymes are endogenously produced mesophilic hydrolytic enzymes derived from at least one fungal strain. The fungal strain is selected from the group consisting of Trichoderma, Aspergillus, Humicola, Chrysosporium, Doratomyces, Fusarium, Gliocladium, Geomyces, Hypocrea, Magnaporthe, Mucor, Neurospora, Ophiostoma, Penicillium, Phoma, Phanerochaete and Emericella fungal strains. The fungal strain is Trichoderma reesei. The endogenous enzymes are selected from the group consisting of: 1 open reading frame (ORF) 123283 Arabinofliranosidase (ABFI) 51.1/6.0 53/6.3 432 38; 2 ORF 76210 Arabinofuranosidase (ABFII) 34.8/6.4 33/6.717634; 3 ORF 55319 Arabinofuranosidase (ABFIII) 53.1/5.7 55/5.5 168 16; 4 ORF 54219 Candidate acetyl xylan esterase (AXE) 21.9/6.2 27/6.2 222 19; 5 ORF 123989 Cellobiohydrolase I (Cel7A) 54.1/4.6 63/4.5 80 7; 6 ORF 123989 Cellobiohydrolase I (Cel7A) 54.1/4.6 63/4.4 64 8,8; 7 ORF 123989 Cellobiohydrolase I (Cel7A) 54.1/4.6 63/4.6 86 9; 8 ORF 123989 Cellobiohydrolase I (Cel7A) 54.1/4.6 57/4.7 107 13; 9 ORF 72567 Cellobiohydrolase II (Cel6A) 49.6/5.1 56/5.2 210 24; 10 ORF 72567 Cellobiohydrolase II (Ce16A) 49.6/5.1 58/5.0 153 11; 11 ORF 72567 Cellobiohydrolase II (Ce16A) 49.6/5.1 59/4.8 207 18; 12 ORI 72567 Cellobiohydrolase II (Ce16A) 49.6/5.1 58/6.0 165 17; 13 ORF 72567 Cellobiohydrolase II (Cel6A) 49.6/5.1 55/5.6 125 11; 14 ORF 72567 Cellobiohydrolase II (Ce16A) 49.6/5.1 55/5.4 77 4; 15 ORF 72567 Cellobiohydrolase II (Ce16A) 49.6/5.1 42/4.7 157 20; 16 ORF 72567 Cellobiohydrolase II (Ce16A) 49.6/5.1 38/4.9 279 17; 17 ORF 72567 Cellobiohydrolase II (Cel6A) 49.6/5.1 38/5.0 307 20; 18 ORF 72567 Cellobiohydrolase II (Cel6A) 49.6/5.1 30/5.1 279 17; 19 ORF 122081 Endoglucanase I (Cel7B) 48.2/4.7 55/4.6 57 9; 20 ORF 120312 Endoglucanase II (Cel5A) 44.1/5.0 43/4.8 160 31; 21 ORF 120312 Endoglucanase II (Cel5A) 44.1/5.0 48/4.6 64 12; 22 ORF 123232 Endoglucanase III (Ce1I2A) 25.1/6.7 25/5.7 185 19; 23 ORF 123232 Endoglucanase III (Ce112A) 25.1/6.7 26/57 185 19; 24 ORF 49081 Xyloglucanase (Ce174A) 87.1/5.4 96/5.4 201 16; 25 ORF 49081 Xyloglucanase (CC174A) 36.2/8.7 96/5.3 520 26; 26 ORF 49081 Xyloglucanase (Ce174A) 36.2/8.7 43/5.2 406 21; 27 OR 49081 Xyloglucanase (Ce174a) 36.2/8.7 35/6.0 354 12; 28 ORF 27554 Candidate Endoglucanase (EGL) 36.2/8.7 36/5.5 87 15; 29 ORF 121127 Xylosidase I (BXLI) 87.2/5.5 97/5.6 208 12; 30 ORF 121127 Xylosidase I (BXLI) 87.2/5.5 97/5.7 203 15; 31 ORF 4223 Xylanase I (XYNI) 24.6/5.0 21/4.6 85 16; 32 ORF 123818 Xylanase II (XYNII) 24.1/7.9 21/6.6 212 27; 33 ORF 11849 Xylanase IV (XYNIV) 52.8/5.7 55/5.6 125 13; 34 ORF 56996 Mannanase I (MANI) 40.2/5.1 53/5.1 147 17; 35 ORF 76672-Glucosidase (BOL1) 78.4/6.4 81/6.7 440, and combinations. The fungal strain is a recombinant fungal strain capable of producing the thermophilic hydrolytic enzymes. The thermophilic hydrolytic enzymes comprise thermophilic xylanase B (XynB) derived from Diclyoglomus thermophilum. The thermophilic hydrolytic enzymes are derived from at least one bacterial strain. The bacterial strain is selected from the group consisting of Acetogenium kuvui, Acetomicrobium faecalis, Acidothermus cellulolyticus, Anaerocellum thermophilum, Chioroflexus auranticus, Desulfotomaculum nigrificans, Desulfovibrio thermophilus, Dictyoglomus thermophilum, Dictyoglomus thermophilum strain Rt46B.1, Bacillus acidocaldarius, Bacillus stearothermophilus, Bacillus caldolyticus, Bacillus caldotenax, Bacillus caldovelox, Bacillus thermoglucosides, Bacillus thermoglucosidasius, Bacillus thermocatenulatus, Bacillus schlegelii, Bacillus flavothermus, Bacillus tusciae, Bacillus sp. KSM-S237, Caldicellulosiruptor saceharolyticus (formerly known as Caldocellum saccharolyticum), Caldicellulosiruptor strain Rt69B.1, Caldicellulosiruptor strain Tok7B.1, Clostridium stercorarium, Clostridium thermocellum, Clostridium thermosulfuro genes, Clostridium thermohydrosulfuricum, Clostridium autotrophicum, Clostridium fervidus, Clostridium thermosaccharolyticum, Caldobacterium hydrogenophilum, Fervidobacterium nodosum, F. islandicum, Rhodothermus marinus, Saccharococcus thermophilus, Streptomyces sp., Synechococcus lividus, Thermoleophilum album, Thermoleophilum minutum, Thermoanaerobium brockii, Thermospiro africanus, Thermoanaerobacter ethanolicus, Thermoanaerobacterium lactoethylicum, Thermodesulfobacterium commune, Thermobacteroides acetoethylicus, Thermobacteroides leptospartum, Thermoanaerobacterium saccharolyticum, Thermotoga maritima, Thermotoga neapolitana, Thermotoga thermarum, Thermus aquaticus, Thermus thermophilus, Thermus ruber, Thermus filiformis, Thermothrix thiopara, Thermomicrobium roseum and Hydrogenobacter thermophilus. The thermophilic hydrolytic enzyme is selected from the group consisting of beta-glucosidase (Bg1A) from Cs. saccharolyticus TP 8.3.3.1, Cellulase/Cellobiohydrolase (celA) from Cs. Saccharolyticus, Arabinofuranosidase (xynF) from Cs. Saccharolyticus, Xylanases (xynE and xynl) from Cs. Saccharolyticus, Xylosidase (xynD) from Cs. Saccharolyticus, Cellulases (celEl/2, celECterm and celB5) from Caldicellulosiruptor Tok7B.1 and Mannanase (manA) from Dictyoglomus thermophilum. The polysaccharide is a component of lignocellulosic biomass. The lignocellulosic biomass is pre-treated with a supercritical solvent, acid hydrolysis or base hydrolysis prior to contacting the polysaccharide with the hydrolytic enzymes. The polysaccharide is selected from the group consisting of cellulose, hemicellulose and mixtures. The fragment is selected from the group consisting of oligosaccharides, disaccharides, monosaccharides and mixtures. The disaccharides are selected from the group consisting of sucrose, lactose, maltose, trehalose, cellobiose, laminaribiose, xylobiose, gentiobiose, isomaltose, mannobiose, kojibiose, rutinose, nigerose, and melibiose. The monosaccharides are selected from the group consisting of trioses, tetroses, pentoses, hexoses, heptoses, octoses and nonoses. It comprises an additional step of contacting the polysaccharide with an enzyme derived from a psychrophilic microorganism and incubating the polysaccharide and enzyme at a temperature suitable for the activity of the enzyme. In producing a fermented sugar product, fermenting is performed utilizing a microorganism selected from the group consisting of fungi, bacteria or combinations. The fungi are selected from the group consisting of Basidiomycetes, Trichocladium, Geotrichum, Aspergillus, Penicillium, Fusarium, Saccharomyces, Candida, Kluvyeromyces, Pachysolen and Pichia. The bacteria are selected from the group consisting of Zymomonas, Leuconostoc, Lactobacillus, Qenococcus, and Mycobacterium. The fermented sugar product is an alcohol or an organic acid. The alcohol is selected from the group consisting of xylitol, mannitol, arabinol, butanol and ethanol. EXAMPLE - No suitable example given.