TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Composition: The fertilizer comprises 2.0x 109 and above a45; where the content of the total nitrogen is 33.1 g/kg; the content of the total phosphorus is 13.3 g/kg; and the content of the total potassium is 21.3 g/kg. The germination index of the decomposed pig manure compost, or decomposed dairy manure compost is 98% above; the organic substance mass ratio content is not less than 35%; the organic nitrogen mass ratio content is 1.2-2%; and the water content is 25-30%. Preferred Process: The microbial organic fertilizer for preventing hot pepper bacterial wilt is prepared by: (a) inoculating the strain a45 to the potato dextrose agar (PDA) culture liquid to perform a liquid fermentation production; where in fermentation, the initial pH is 7.0-7.2; the culture temperature is 30 degrees C; and the speed is 170 rotations/minute; the spore is formed during the middle and later stage of the fermentation; and the a45 antagonistic bacterial liquid obtained from the fermentation contains bacteria or spores is not less than 5x 109/ml; (b) preparing the organic fertilizer: mixing decomposed pig manure compost, decomposed dairy manure compost, and amino acid organic fertilizer based on the ratio of 3:3:4; and (c) inoculating the a45 antagonistic bacterial liquid to the organic fertilizer based on the volume mass ratio of 20% to perform a solid fermentation at 30-50 degrees C; where in the fermentation process, the compost is turned once each day; the fermentation period is 5-7 days so that the antagonistic bacteria content reaches 2.0x 109/g above; the water content is evaporated to 30% below at 60 degrees C or below; and the product is packed to obtain the microbial organic fertilizer for preventing hot pepper bacterial wilt. Preparing the PDA culture liquid used in (a) comprises preparing the 1 L culture medium by taking out and peeling off 200 g of potatoes; cutting into small cubes and cooking into the water for 30 minutes after boiling; after filtering, adding 20 g of common sucrose into the filtered liquid and enabling the constant volume to be 1000 ml; adjusting the pH to 7.2-7.4, and disinfecting it at 121 degrees C for 20 minutes. ACTIVITY - Plant Protectant; Antibacterial.