TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preparation (Claimed): Preparation of (I) comprises: (a) mixing a predetermined amount of N-methyl-aminoethanol with a predetermined amount of methanol to form a first mixture; (b) adding a predetermined amount of sulfuric acid into the first mixture to form a second mixture; (c) adding a predetermined amount of cyanamide into the second mixture to form a third mixture; (d) adding a predetermined amount of ethanol into the third mixture to form a crystallized creatinol sulfate; (e) drying the crystallized creatinol sulfate to obtain a final product of creatinol sulfate having 60-80% of yield rate. Preferred Process: The sulfuric acid is mixed with the N-methylamino-ethanol before the N-methyl-amino-ethanol chemically reacts with the cyanamide to form the creatinol sulfate. In the method, a predetermined amount of methanol is mixed with the N-methyl-amino-ethanol before the N-methyl-amino-ethanol is chemically reacted with the sulfuric acid; and a predetermined amount of ethanol is added into the N-methyl-amino-ethanol, where the sulfuric acid, and the cyanamide to crystallize the creatinol sulfate. The mole ratio of the N-methyl-aminoethanol, the sulfuric acid, and the cyanamide is 2:1:2. In step (b), the sulfuric acid is added by slowing dropping the sulfuric acid into the first mixture. In the method, before the step (b), the first mixture is cooled down at below 10 degrees C. The step (b) further comprises: stirring the second mixture at room temperature for 0.5-1 hour; and heating up the second mixture at 30-70 degrees C before the cyanamide is added to it. The step (c) further comprises: adjusting pH value of the third mixture to 6.5-7; and evaporating water from the third mixture. The pH value of the third mixture is adjusted by additional sulfuric acid. The step (d) further comprises: cooling down the third mixture at below 20 degrees C; removing the crystallized creatinol sulfate from the third mixture; and rinsing the crystallized creatinol sulfate. The crystallized creatinol sulfate is rinsed by additional ethanol. In step (d), the ethanol is added into the third mixture to precipitate out the creatinol sulfate when the third mixture is warm. ACTIVITY - Plant Growth Regulant; Anabolic.    MECHANISM OF ACTION - None given.    EXAMPLE - N-methyl-amino-ethanol (37.5 g) and methanol (20 ml) were mixed to form a mixture. The mixture was cooled down at below 10 degrees C. Concentrated sulfuric acid (14 ml) was added into the mixture by slowly dropping the sulfuric acid into the mixture and stirring the mixture for 0.5-1 hour. The mixture was heated at 50 degrees C. Cyanamide (80.5 ml) was slowly added into the mixture and kept the mixture at reaction temperature for 1-5 hours. The pH value of the mixture was adjusted to 6.5-7 by adding concentrated sulfuric acid in it. The pressure of the reaction was reduced and the water was evaporated. Ethanol (100 ml) was added into the mixture and the mixture was kept at 30-70 degrees C, to precipitate out creatinol sulfate. The mixture was cooled down at below 20 degrees C. The crystallized creatinol sulfate was removed by filtration. The crystallized creatinol sulfate (65 g, 78%) was rinsed by additional ethanol.