NOVELTY - Method of manufacturing fuel cell involves (a) adding selected quantity of yeast cells and yeast nutrient source to initial anode solution in anode chamber, (b) connecting resistor across the anode and cathode to enable poising of the anode and formation of yeast biofilm on the anode, (c) replacing the anode solution with replacement quantity of initial anode solution, (d) adding selected quantity of the yeast nutrient source to the replacement quantity of initial anode solution, (e) continuing to run the fuel cell, and (f) repeating steps (c) and (d).    USE - The method is useful for manufacturing fuel cell, preferably microbial fuel cell (claimed) used for converting biomass energy into electrical energy.    ADVANTAGE - The fuel cell has high power density.    DETAILED DESCRIPTION - Method of manufacturing fuel cell involves (a) adding selected quantity of yeast cells and yeast nutrient source to initial anode solution in anode chamber, (b) connecting resistor across the anode and cathode to enable current flow for predetermined time interval to enable poising of the anode and formation of yeast biofilm on the anode, (c) replacing the anode solution with replacement quantity of initial anode solution, (d) adding selected quantity of the yeast nutrient source to the replacement quantity of initial anode solution, (e) continuing to run the fuel cell for predetermined time interval at a resistance of 10-10000 ohms, and (f) repeating steps (c) and (d) until the yeast has formed a desired biofilm on the anode. An INDEPENDENT CLAIM is included for microbial fuel cell, which comprises (a) (i) anode chamber having an anode in anode solution, (ii) cathode chamber having cathode in a cathode solution, (iii) proton conducting membrane positioned in communication between the anode chamber and the cathode chamber, and (iv) anode including a yeast cell biofilm adherent or (b) anode component and cathode component, where the anode component including an anode structure with a yeast biofilm adherent.