NOVELTY - Polypeptide having oxidoreductase activity comprising an amino acid sequence of SEQ ID NO: 3 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 4 or its variant polypeptide having at least 45% sequence identity with the sequence of SEQ ID NO: 3 (Sequences not defined here may be found at ftp://ftp.wipo.int/pub/published_pct_sequences/publication), is new.    USE - The polypeptide is useful in the production of FDCA and HMF acid (all claimed), where the FDCA is useful e.g.: as an alternative for terephtalate in the production of polyesters; as a substrate for a large variety of valuable compounds e.g. succinic acid, 2,5-bis(aminomethyl)-tetrahydrofuran, 2,5-dihydroxymethyl-tetrahydrofuran, 2,5-dihydroxymethylfuran and 2,5-furandicarbaldehyde; in the production of coatings e.g. in alkyd resin and thermoplastic coatings; and as a xylene equivalent in biofuels and as solvent.    ADVANTAGE - The polypeptide: has oxidoreductase activity which has high region specificity; and provides FDCA or HMF acid, by avoiding the substantial amount of by-product.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for:    (1) a polynucleotide comprising: (a) the nucleotide sequence of SEQ ID NO: 4; (b) a nucleotide sequence which hybridizes selectively with a polynucleotide being the reverse complement of SEQ ID NO: 4; (c) a nucleotide sequence having at least 66% sequence identity with the nucleotide sequence of SEQ ID NO: 4; (d) a fragment of a nucleotide sequence in (a) or (b) which is at least 100 nucleotides in length; (e) a sequence which is degenerate as a result of the genetic code to a sequence of (a), (b), (c) or (d); and (f) a nucleotide sequence which is the reverse complement of a nucleotide sequence in (a), (b), (c), (d) or (e);    (2) a polynucleotide which encodes the polypeptide;    (3) a nucleic acid construct comprising the polynucleotide;    (4) a vector incorporating the polynucleotide sequence or the nucleic acid construct;    (5) a cell comprising the polypeptide, the polynucleotide, the nucleic acid construct or the vector;    (6) preparing of the polypeptide having oxidoreductase activity;    (7) producing 2,5-furandicarboxylic acid (FDCA) comprising reacting at least one furanic precursor of FDCA with an oxidant in the presence of an oxidoreductase catalyst and optionally at least one coenzyme to give FDCA, where the oxidoreductase catalyst comprises the polypeptide;    (8) producing 5-hydroxymethyl-2-furancarboxylic acid (HMF acid) comprising reacting at least one furanic precursor of HMF acid with an oxidant in the presence of an oxidoreductase catalyst and optionally at least one coenzyme cofactor to give HMF acid; and    (9) producing a polymer from at least one monomer, where the monomer is FDCA.