NOVELTY - Producing the depressant drug fluoxetine includes amine decomposition, catalytic hydrogenation, and aromatic hydrocarbon etherification reaction.    USE - Method for producing the depressant drug fluoxetine (claimed).    ADVANTAGE - The method has reduced pollution, improved reaction converting rate, and improved output of target product, and reduced catalyst poisoning.    DETAILED DESCRIPTION - Producing the depressant drug fluoxetine comprises: (A) throwing the B-chloro benzyl methyl ketone to a high pressure reactor with the Teflon (RTM: PTFE) bushing; adding the solvent; sealing the reactor; exchanging the air in the reactor with the nitrogen for 3-5 times; sending the methylamine to replace the nitrogen for 3-5 times; and adjusting the pressure of the reactor to the determined pressure; opening a stirrer; (B) increasing the temperature slowly to the reaction temperature; reducing the reaction temperature to room temperature after reaction is performed for 10-12 hours; using the nitrogen to replace the air in the system for 3-5 times; throwing in the load catalyst; and adding the alkali material; (C) sealing the high pressure reactor; utilizing the high pure nitrogen to replace the air in the high pressure reactor for 3-5 times; using the hydrogen to replace the nitrogen for 3-5 times; and charging the hydrogen for 6-10 hours; (D) adjusting the pressure of the hydrogen during the reaction process; maintaining the pressure unchangeable; adjusting the temperature to the aromatic hydrocarbon etherification reaction temperature after reaction is ended; (E) dropping the p-chlorotrifluoromethylbenzene; controlling the reaction temperature; ending the reaction after the reaction is performed for 5-7 hours; and cooling the reactor to the room temperature; performing extraction by the ethyl acetate; and (F) combining the extraction solution; cleaning it by the water; drying it by the anhydrous sodium sulfate; decoloring the active carbon and pouring it to the single-opening bottle; stirring the mixture and sending the hydrogen chloride; adjusting pH to 4; generating the sediment; filtering it; cleaning the cake by the acetone; and drying at vacuum degree to obtain the white solid.