TECHNOLOGY FOCUS - INSTRUMENTATION AND TESTING - Preferred Components: The condenser train comprised of: a first set of at least one condenser, that is maintained at a temperature to promote the rapid cooling of pyrolysis vapors entering the condenser at 300-450 degrees C which decreases the temperature of vapors exiting the condenser to 110-120 degrees C; and a second set of at least one condenser, of a multiple condenser train that is maintained at a temperature to continue cooling of pyrolysis vapors entering a second set of at least one condenser at 110-120 degrees C which decreases the temperature of vapors exiting the condenser to a temperature of 30 degrees C. The condensers, other than the condenser containing bio-oil with high water content, contain a bio-oil with low water content.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Process: The step of manipulating the temperature of at least one condenser causes differential condensation of bio-oil vapor components in the condenser. The water content of a pyrolysis vapor stream is further condensed into at least one condenser in a multiple condenser train, the water content of sufficient magnitude to cause spontaneous self fractionation of the bio-oil contained in the condenser. The high water content bio-oil contained in at least one condenser self fractionates to provide anhydrosugar-rich aqueous fraction and pyroligneous fraction. The self-fractionated pyroligneous fractions from the condenser of a multiple condenser train are combined with low water content bio-oils to produce a low water content bio-oil. The pyroligneous fraction, still containing water soluble chemical compounds, is further fractionated to produce an aqueous fraction with the resulting aqueous and pyroligneous fractions being useful for further processing. The subsets of the fractionated bio-oils can be further processed. The combined bio-oils are further fractionated by water fractionation or other method of fractionation. The combined bio-oils are processed without further fractionation. In the method-1, green or wet biomass can be pyrolyzed with water content of bio-oil maintained below 30%, by collection and separation from the bio-oil, of excess water in the aqueous fraction in the at least one condenser. The pyroligneous fraction that is not condensed into the aqueous fraction condenser is improved for later production of fuels and/or chemical products by removal of the anhydrosugar-rich aqueous fraction from the total bio-oil. In the method-2, the feedstock is a biomass of high moisture content; and the liquid injected into the pyrolysis vapor stream optimizes anhydrosugars production, where the liquid is water, an acidic solution or a basic solution, and contains a catalyst for the purpose of reducing the thermal degradation of the anhydrosugars contained in the pyrolysis vapor stream. In the method-2, the gas injected into the pyrolysis vapor stream contains a catalyst for the purpose of reducing the thermal degradation of the anhydrosugars contained in the pyrolysis vapor stream; the liquid is injected into the vapor stream by a mechanism that atomizes the liquid into small droplets suitable for heat transfer within the pyrolysis vapor stream; and a reduction of secondary and tertiary reactions further improves the properties of the pyroligneous components of the condensed bio-oil. The liquid or gas injected into the pyrolysis vapor stream decreases secondary and tertiary decomposition reactions of the anhydrosugars in the quenched vapor. The method-2 further comprises pretreatment of a feedstock to optimize the efficacy of the catalyst or to increase the production of anhydrosugars content, where the feedstock is any type of biomass or product derived from biomass. The pretreatment is applied by ultrasound, ultrasonic agitation, sonication or microwave excitation. The pretreatment is performed by mechanical methods, such as high shear stirring or mixing. Preferred Components: The separate fractions can include condensates with a high proportion of pyroligneous compounds. The separate fractions include condensates with a high proportion of aqueous compounds.