TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The hydrogen-containing stream that contains not greater than 200 vppm CO, based on total volume of the hydrogen-containing stream, is added to the hydroprocessing zone during hydroprocessing. The hydrogen-containing stream that is added to the hydroprocessing zone during hydroprocessing contains greater than 60 vol.% H2, based on total volume of the hydrogen-containing stream. The hydroprocessing zone contains cobalt-molybdenum (CoMo) or nickel-molybdenum (NiMo) hydroprocessing catalyst.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The method involves separating at least a portion of the gas fraction from the hydroprocessed product; removing at least a majority of carbon monoxide (CO) contained in the separated gas fraction to form a treated gas stream; providing at least a portion of the treated gas stream to the hydroprocessing zone; and recovering at least a portion of the liquid fraction. The hydroprocessing produces a hydroprocessed product comprised of a liquid fraction, and a gas fraction which is separated from the liquid fraction with at least a portion of the liquid fraction forming the transportation fuel, where at least a portion of the separated gas fraction is acid gas treated prior to removing the CO. The separated gas fraction is treated or contacted with a membrane or an adsorbent to remove at least a majority of the CO from the gas stream to form a treated gas stream, with the treated gas stream containing greater than 60 vol.% H2 and not greater than 200 vppm CO based on total volume of the treated gas stream. Where the separated gas fraction is treated or contacted with an adsorbent that is contained in a pressure swing adsorption system or a rapid cycle pressure swing adsorption system to form the treated gas stream; and at least a portion of the treated gas stream is added to the hydroprocessing zone during hydroprocessing. Preferred Components: The feedstock includes at least 0.05 wt.% lipid material, based on total wt. of the feedstock. The lipid material portion of the feedstock is comprised of at least 20 wt.% fatty acid alkyl ester, based on total wt. of the lipid material in the feedstock. EXAMPLE - No suitable example given.