TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Process: The reduction is carried out in the presence of an optically inactive reducing agent to form substituted indan-1-yl-prop-2-ynyl-amine compound of formula (V) and resolving the compound (V) with a chiral resolving agent to form the compound(I). The reduction is carried out in the presence of optically active reducing agent to form the compound (I). The compounds obtained are converted into salts. Preferred Components: The salt is the mesylate or tartrate salt. ACTIVITY - Antiparkinsonian; Antidepressant; Nootropic; Tranquilizer; Cerebroprotective; Neuroprotective. No biological data given.    MECHANISM OF ACTION - Monoamine oxidase inhibitor.    ADMINISTRATION - The composition is administered by oral, rectal, parenteral (including intravenous, intramuscular, subcutaneous, intracisternal, intravaginal, intraperitoneal or local), ophthalmic, transdermal, sublingual, buccal or nasal route. No dosage details given.    SPECIFIC COMPOUNDS - Preparation of 6 compounds is specified as (I) e.g. rasagiline (I'), ladostigil, rasagiline mesylate, rasagiline tartrate, ladostigil mesylate.    EXAMPLE - 1-Indanone (50 g), titanium(IV) isopropoxide (128.9 g) and propargyl amine (20.8 g) were taken in absolute ethanol (500 ml) and the mixture was stirred at 25-30 degrees C for 8 hours to obtain the titanium complex. This titanium complex was reduced by adding sodium borohydride (21.45 g) at 25-30 degrees C. The mixture was further stirred at 25-30 degrees C for 8 hours. The reaction mass was quenched by adding in a mixture of aqueous ammonia solution (100 ml) and ethyl acetate. The precipitated inorganic solid was filtered. The organic layer was separated. The organic layer was extracted with 16 wt./wt.% aqueous hydrochloric acid. The aqueous extract was basified to pH 7.5-8 with aqueous ammonia solution and extracted with cyclohexane. The cyclohexane extract was concentrated at 40-45 degrees C to obtain the rasagiline base as oily residue having purity of 98% determined by HPLC.