NOVELTY - A solid-based monolithic catalyst is obtained by using honeycomb ceramics having standard straight pore canal as carrier, and load-type hydrotalcite and hydrotalcite-like solid base as active component. The honeycomb ceramics comprise honeycomb ceramics having different apertures. The load-type hydrotalcite and hydrotalcite-like solid base are obtained by using hydrotalcite and hydrotalcite-like compound, or calcined hydrotalcite and hydrotalcite-like compound as carrier.    USE - Solid-based monolithic catalyst is used for biodiesel.    ADVANTAGE - The solid-based monolithic catalyst having excellent productivity and durability, is economically manufactured by simple and environmentally-friendly process, with reduced energy consumption.    DETAILED DESCRIPTION - A solid-based monolithic catalyst is obtained by using honeycomb ceramics having standard straight pore canal as carrier, and load-type hydrotalcite and hydrotalcite-like solid base as active component. The honeycomb ceramics comprise honeycomb ceramics having different apertures chosen from cordierite, mullite, aluminum oxide and zirconium oxide. The load-type hydrotalcite and hydrotalcite-like solid base are solid-based catalyst using hydrotalcite and hydrotalcite-like compound, or calcined hydrotalcite and hydrotalcite-like compound as carrier and loading potassium fluoride, sodium fluoride, calcium fluoride, sodium carbonate, potassium carbonate, zinc fluoride base metals, and/or rare-earth metal salts. An INDEPENDENT CLAIM is included for manufacture of monolithic catalyst, which involves mixing adhesive with load-type hydrotalcite and hydrotalcite-like solid base, preparing suspension slurry, pre-treating honeycomb ceramic carrier, soaking in suspension slurry for 15-60 minutes, blowing residual liquid between pore canals, and drying. The granularity of load-type hydrotalcite and hydrotalcite-like solid base is 100 meshes or more. The composition of adhesive is inorganic adhesive of alumina sol or sodium silicate.