TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Composition: The mass ratio of the cyanoacetic acid salt derivative to 2-bromo-methoxyl naphthalene is 1.1:1.5. The mole ratio of the solvent to 2-bromo-methoxyl naphthalene is 0.5:2. The quantity of palladium catalyst is 0.1-0.4 mol.% of the quantity of 2-bromo-methoxyl naphthalene. The quantity ratio of organic phosphine ligand to palladium catalyst is 1:1 to 3:1. The solvent is at least one of benzene, methylbenzene, dimethylbenzene, trimethylbenzene, dimethyl sulfoxide , dimethylformamide, dimethylacetylamide, N-methylpyrrolidone, diethylene glycol dimethyl ether, diethylene glycol diethylethe, triethylene glycol dimethyl ether, and dipropyl glycol diethylethe. The palladium catalyst is at least one of metal palladium, palladium acetate, palladium chloride, di(acetonitrile) palladium dichloride, palladium trifluoroacetic acid, tri(dibenzylidene acetone) dipalladium, dipalladium, diallyl palladium dichloride, and di(dibenzylidene acetone) palladium. The organic phosphine ligand is at least one of triphenyl phosphine, tricyclohexyl phosphine, tritertiary butyl phosphine, 2-dicyclohexyl phosphine-2,4,6-triisopropyl biphenyl, 2-dicyclohexyl phosphine-2',6'-dimethoxyl biphenyl, 2-(di tertiary butyl phosphine) biphenyl, 2-(dicyclohexyl phosphine) biphenyl, 2-dicyclohexyl phosphine-2(N,N-dimethyl amido) biphenyl, 9,9-dimethyl-4,5-di(diphenyl phosphine) xanthene, 9,9-dimethyl-4,5-di(ditertiary butyl phosphine) xanthene, 2-dicyclohexyl phosphine xanthene, 2-dicyclohexyl phosphine-2',6'-diisopropoxy-1,1'-biphenyl, ( plus minus )-2,2-di-(diphenylphosphino)-1,1-binaphthalene, ( plus minus )-2,2-di-(di-p-tolylphosphino)-1,1-binaphthalene and 1,1'-di(diphenyl phosphine) ferrocene. Preferred Process: The process in (b) specifically comprises performing the heating reflow on the naphthalene derivative in the strong acid aqueous solution to carry out the hydrolysis reaction to generate naproxen; where the strong acid is at least one of sulfuric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, and perchloric acid; the quantity of the strong acid substance is 2-5 times of the quantity of the substance of the naphthalene derivative; and the concentration of strong acid is 1-3 mol/L based on the hydrogen ion concentration. In (b), the naphthalene derivative is processed with the heating reflowing in the strong alkali aqueous solution on the existence of solvent ethanol to generate a hydrolysis reaction and it is further protonized by the strong acid to obtain naproxen; where the strong alkali is at least one of sodium hydroxide, potassium hydroxide, potassium tert-butoxide, sodium tert-butoxide, and potassium ethoxide; the quantity of the strong alkali substance is 2-5 times of the quantity of the substance of the naphthalene derivative; the concentration of the strong alkali is 1-3 mol/L based on the concentration of hydroxyl ions; the volume of the assistant solvent ethanol is 1/10 to 1/2 of the volume of the strong alkali aqueous solution; the strong acid for protonation is at least one of sulfuric acid, hydrochloric acid, hydrobromic acid, and perchloric acid; and the quantity of the strong acid is 1.2-1.5 times of the quantity of the strong alkali substance. Preferred Conditions: The reaction temperature is 120-160 degrees C, preferably 100-150 degrees C; and the reaction time is 16-24 hours, preferably 5-15 hours.