NOVELTY - Manufacture of bio-diesel oil comprises mixing isoamylol with tetrahydrofuran at ratio of 3-7:7-3, generating cosolvent A, mixing with methyl alcohol with cosolvent A at ratio of 1-3:1 to form modified alcohol B, pumping raw material oil and C product to supporting device D for quickly producing bio-diesel oil and carrying out ester exchange reaction to obtain semi-product E; and recycling methyl alcohol and cosolvent of bio-diesel oil F by distilling, entering recycled methyl alcohol and cosolvent in raw material cylinder, and reacting at 10-30 degrees C under normal pressure.    USE - Method for manufacturing bio-diesel oil (claimed).    ADVANTAGE - The method has simple reaction process, quick property, high efficiency and low cost.    DETAILED DESCRIPTION - Manufacture of bio-diesel oil comprises mixing isoamylol with tetrahydrofuran at ratio of 3-7:7-3, generating cosolvent A, mixing with methyl alcohol with cosolvent A at ratio of 1-3:1 to form modified alcohol B, and mixing modified alcohol B with sodium lauryl sulfate and sodium hydroxide at ratio of 1:1-10 to obtain mixture C; pumping raw material oil and C product to supporting device D for quickly producing bio-diesel oil and carrying out ester exchange reaction to obtain semi-product E, separating glycerol of semi-product E to obtain bio-diesel oil F and rough glycerol G; recycling methyl alcohol and cosolvent of bio-diesel oil F by distilling, obtaining bio-diesel oil H of product, with recycled methyl alcohol and cosolvent entering raw material cylinder to circularly use, and recycling methyl alcohol and cosolvent of rough glycerol G by distilling to obtain industrial-level glycerol I; and entering recycled methyl alcohol and cosolvent in raw material cylinder to circularly use, with time from measurement pump for pumping material to device D to material outputted from high-efficiency pipeline reactor for 10-20 seconds, as ester exchange reaction time, and reacting at 10-30 degrees C under normal pressure.