TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: The method further involves processing the lipids to form EPA- and/or DHA-containing products for human consumption or animal feeds. The extracting step is carried out using methods chosen from chromatography, fractional or molecular distillation, enzymatic splitting, low-temperature crystallization, supercritical fluid extraction and urea complexation. The growing step involves culturing the algae in a successive scale-up system, involves (a) inoculating the algae in a volume of 50-200 ml, (b) transferring the algae culture to a vessel, open pond, or raceway which is 2-20 times larger in volume when the algae concentration reaches 50-1000 mg/l, where the transferring step is repeated until a desired amount of algae is grown, and (c) harvesting the algae as a single batch or semi-batch wise, where a fraction of the algae is harvested daily and replaced with additional water and nutrients. The harvesting step involves controllably feeding the algae to the fish while the fish is growing from fry to juvenile, from juvenile to adult, from fry to adult or to adult grow-out until at least 50% of a dominant species within the population reaches a fish biomass set point, where the fish biomass set point is determined by mass, density, lipid content or lipid profile. The harvesting step involves feeding the algae to the fish based on algal biomass set point, where the algal biomass set point is determined by mass, density, lipid content or lipid profile. The harvesting step involves gathering the fish that reaches a fish biomass set point. The growth of the algae is controlled by manipulation of one or more cultivation conditions chosen from nutrient concentration, salinity, alkalinity, pH, temperature, carbon dioxide concentration or their combinations. The growing step and harvesting step are carried out simultaneously in the first enclosed-container system or open-pond system. The fish feed on the algae continuously. The growing step and harvesting step are carried out successively in the first enclosed-container system or open-pond system, and the second enclosed-container system or open-pond system, respectively. The harvesting step involves transferring a portion or entire population of fish to second enclosed-container system or open-pond system having lower loading density than the first enclosed-container system or open-pond system. The harvesting step further involves restocking the system with the algae and/or fish. The harvesting step further involves increasing or decreasing the number of fish of one or more species based on algal biomass set point, and feeding the fish in first or second enclosed-container system or open-pond system comprising the algae at a concentration of 10-1000 mg/l. The extracting step involves heating the fish to 70-100 degrees C, pressing the fish to release the lipids, and separating the lipids from an aqueous phase and/or a solid phase. The extracting step involves preparing a fishmeal composition from the fish, treating the fishmeal composition with near-critical or supercritical water, and separating the lipids from an aqueous phase and/or a solid phase. The algae and the population of fish are indigenous to the coast. The algae and the population of fish are growing in one of the enclosures and the fish feed on the algae continuously. The fish biomass set point is 2-week weight, 2-week length, 2-week body depth, 2-week fat content, 4-week weight, 4-week length, 4-week body depth, 4-week fat content, 8-week weight, 8-week length, 8-week body depth, 8-week fat content, 3-month weight, 3-month length, 3-month body depth, 3-month fat content, 6-month weight, 6-month length, 6-month body depth or 6-month fat content. The algal biomass set point is the 2-week weight, 2-week length, 2-week body depth, 2-week fat content, 4-week weight, 4-week length, 4-week body depth, 4-week fat content, 8-week weight, 8-week length, 8-week body depth, 8-week fat content, 3-month weight, 3-month length, 3-month body depth, 3-month fat content, 6-month weight, 6-month length, 6-month body depth or 6-month fat content. Preferred Organisms: The algae are prokaryotic, eukaryotic, microalgae, Cyanophyceae, Skeletonema, Trichodesmium, Cryptosphaeria, Coelastrum, Chlorosarcina, Micractinium, Porphyridium, Nostoc, Closterium, Elakatothrix, Cyanosarcina, Trachelamonas, Euglena, Phacus, Synechocystis, Oscillatoria, Lyngbya, Kirchneriella, Carteria, Cryptomonas, Chlamydamonas, Synechococcus, Crococcus, Anacystis, Calothrix, Planktothrix, Anabaena, Hymenomonas, Isochrysis, Pavlova, Monodus, Monallanthus, Platymonas, Amphiprora, Chaetoceros, Pyramimonas, Nannochloropsis, Gymnodinium , Alexandrium, Cochlodinium, Dinophysis, Gyrodinium, Prorocentrum, Chattonella, Heterosigma, Glyphodesmis, Synedra, Neidium, Pinnularia, Stauroneis, Papiliocellulus, Scolioneis, Fallacia, Surirella, Entomoneis, Auricula, Stephanodiscus, Chroococcus, Staurastrum, Netrium, Chlorella, Amphora, Cymbella, Thalassiosira, Cylindrotheca, Rhodamonas, Nannochloropsis, Nitzchia, Pseudonitzchia, Navicula, Craticula, Gyrosigma, Pleurosigma, Melosira, Cosnodiscus, Haematococcus, Botryococcus and/or Tetraselmis. The algae and fish are freshwater species, marine species, briny species or species that live in brackish water. The fishes are belonging to order chosen from Clupeiformes, Siluriformes, Cypriniformes, Mugiliformes and/or Perciformes. The fish is chosen from menhadens, shads, herrings, sardines, hilsas, anchovies, catfish, carps, milkfish, paddlefish, shiners and/or minnows. Preferred System: The system further comprises unit for processing the lipids. ACTIVITY - Cardiovascular-Gen.; Antiarthritic; Hypnotic; Hypotensive; Antilipemic; Antiarrhythmic; Cardiant; Vasotropic; Antidepressant; Anabolic; Eating-Disorders-Gen.; Neuroleptic; Nootropic; Tranquilizer. No biological data given.    MECHANISM OF ACTION - None given.    EXAMPLE - No suitable example given.