TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The bioactive substance is an acidic compound having acid dissociation constant (pKa) of 7 or less. The additive or modifier comprises polyethylene glycol, polypropylene glycol, polyvinyl alcohol, polyacrylates, 6C fatty acids, 6C alkyl amines, biopolymers comprising cellulose, starch, chitin, chitosan, lignin and proteins, minerals comprising vermiculite, kieselguhr, montmorillonite, and talc, resins comprising dammar, olibanum, myrrh, galipot, and rosin, paraffin or its mixture and condensates or copolymers. The carboxylic acid or its ester or its anhydride is aliphatic or aromatic in nature containing 6-24C saturated or unsaturated, straight chain or branched and their mixtures. The amino compound is monomeric or oligomeric, and contains at least 1 or 2 primary and 1 or 2 secondary amines. The amino compound is monomeric or oligomeric, and contains at least one primary or secondary amine and one hydroxyl function. The amino compound is monomeric or oligomeric, and contains at least two hydroxyl functions and one tertiary amine. The matrix is cross-linked with a bi or poly-functional electrophile comprising hexamethylene diisocyanate, epichlorohydrin, adipic acid, sebacic acid, trimellitic acid, or pyromellitic acid. The matrix is further modified by electrophiles comprising acetic anhydride, phenyl isocyanate, chloroacetic acid and their salts, dimethyl sulfate, benzyl chloride, or methyl chloride. The bioactive substance is a pharmaceutical agent, pesticide, herbicide, fungicide, insecticide or nematicide. The additive is anionic, neutral, cationic surfactant or their mixtures. The additive is a solvent. Preferred Composition: The formulation comprises 0-95 wt.% of additive or modifier. The solvent (0-95 wt.%) is chosen from methanol, ethanol, isopropanol, ethyleneglycol, water miscible solvents such as acetone, methylformamide, methylsulfoxide, N-methylpyrrolidone, water immiscible solvents comprising hexane, heptane, toluene, naphta, and their mixtures. The formulation is ground to an average particle size 1 mm or less in diameter. Preferred Method: The formulation is melted by incorporating the bioactive substance. The formulation is melted and sprayed to form granules or particles, which are packaged ready for use. The formulation is melted by applying the bioactive substance to its target.    TECHNOLOGY FOCUS - POLYMERS - Preferred Components: The matrix is of polymeric nature having at least ten similar repeating units. The polymeric backbone is of basic nature. The polymeric backbone is polyamines chosen from polyethylenimine, polypropylenimine, polyvinylamine and polypropylenamine. The polyamine is crosslinked with bi or poly functional agent comprising epichlorohydrin, di or polyepoxide containing diglycidyl glycerol, ethylene glycol diglycidyl or 2-((3-(oxiran-2-ylmethoxy)-2,2-bis(oxiran-2-ylmethoxymethyl)propoxy)methyl)oxirane, di or polycarboxylic acid including phthalic acid, succinic acid, diglycolic acid, or adipic acid, di or polyisocyanate including phenyl diisocyante or poly ((phenyl isocyanate)-co-formaldehyde). The polymeric backbone is grafted with polyethylene glycol, polypropylene glycol, polyvinyl alcohol or their mixtures. The polymeric backbone is of acidic nature. The polymeric backbone is a polycarboxylic acid comprising polyacrylic acid or polymethacrylic acid. The polymeric backbone is a polysiloxane of formula: Rl-(SiR2R3)-O-(SiR4(OH))-R5 (I).R1, R2, R3, R4, R5=H, OH, 1-22C alkyl, l-22C alkoxy, 2-22C alkenyl, aryl, aryloxy (alkyl aryl, alkylaryloxy), alkoxyalkyl, alkoxyallyloxy heteroaryl, or heteroaryloxy.. ACTIVITY - Fertilizer; Pesticide. No biological data given.    MECHANISM OF ACTION - None given.    EXAMPLE - No suitable example given.