NOVELTY - An arbidol mesylate synthesizing method involves providing ethyl acetoacetate as starting material. 6-bromine-5-hydroxyl-1-methyl-1-methyl-2-thiophenyl methyl indole-3-hydroxyl ethyl ester, 33% of dimethylamine solution and 37% of formaldehyde solution are added to glacial acetic acid. The mixture is neutralized and dried to obtain 6-bromine-5-hydroxyl-4dimethylamine methyl-2-thiophenyl indole-hydroxyl ethyl ester that is added with acetone. The acetone added mixture is stirred for 1 hour at 55 degrees C followed by cooling, filtering and drying to obtain the arbidol mesylate.    USE - Arbidol mesylate is used for treating influenza virus.    ADVANTAGE - The method enables synthesizing arbidol mesylate in a simple, easy and environment-friendly manner.    DETAILED DESCRIPTION - An arbidol mesylate synthesizing method involves providing ethyl acetoacetate as starting material and reducing 40% by weight of methylamine water solution while stirring at 20-50 degrees C, and continuously reacting for 3 hours. A lower organic layer is washed by water and dried to obtain 3-formyl amino-ethyl crotonate. Benzoquinone is added to solvent acetone, and 3-formyl amino-ethyl crotonate is added to the mixture while stirring at 25-60 degrees C. The obtained product is continuously reacted for 2 hours to obtain 1,2-dimethyl-5-hydroxy-indole-3-hydroxyl ethyl ester, where the ethyl ester is added to chloroform. The added mixture is stirred until solution is clear, and liquid bromine is added to the stirred mixture to obtain 6-bromine-2 bromine methyl-5-hydroxy-indole-3hydroxyl ethyl ester. Methanol and sodium hydroxide are uniformly stirred by adding phenylthiol for 2 hours. The obtained mixture is added with 6-bromine-2 bromine methyl-5-hydroxy-indole-3hydroxyl ethyl ester and stirred for 3 hours, where the stirred mixture is filtered, and the filter cake is washed by water. The washed filter cake is dried to obtain 6-bromine-5hydroxyl-1-methyl-1-methyl-2-thiophenyl methyl indole-3-hydroxyl ethyl ester. The 6-bromine-5hydroxyl-1-methyl-1-methyl-2-thiophenyl methyl indole-3-hydroxyl ethyl ester, 33% of dimethylamine solution and 37% of formaldehyde solution are added to glacial acetic acid under condition of stirring at 0-5 degrees C and heated at 60-70 degrees C. The added mixture is neutralized and dried to obtain 6-bromine-5-hydroxyl-4dimethylamine methyl-2-thiophenyl indole-hydroxyl ethyl ester that is added with acetone. The acetone added mixture is stirred for 1 hour at 55 degrees C followed by cooling, filtering and drying to obtain the arbidol mesylate.