TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Fertilizer: The seed herb comprises mixed seeds of at least three types of seeds of soapberry seeds, Sophora alopecuroide seeds, Simarubaceae seeds, Camptotheca acuminata Decne seeds and tung tree seeds; the grass or leaf herb is mixture of at least six plants and leaves of the whole plant of Anemone vitifolia, the whole plant of sweet wormwood, Rheum officinale leaves, gingkgo leaves, maple and poplar leaves, thunder god vine leaves, Salix leaves, Macleaya cordata leaves, and peach leaves. The dough is at least one of tea seed cakes, vegetable seed cakes, cotton seed cakes, bean cakes, peanut cakes, and sunflower seed cakes, which is an oil extracted residue. The water soluble antibiotic is ivermectin WP or abamectin WP. The biological organic fertilizer is prepared by: (a) preparing raw materials: collecting the following raw materials according to part by weight: 40-60 parts of animal excrement: collecting single excrement or mixed excrement of pigs, cattle, sheep and horses; 15-20 parts of fowl excrement: collecting single or mixed excrement of ducks and gooses; 15-30 parts of plant straw: crushing wheat straws, rice straws, maize straws, broomcorn straws, or weed straws, cutting or crushing into 2 cm long small sections for use; 1-7 parts of EM strains; 2-5 parts of dough: buying from an oil extraction plant, crushing into less than 100 meshes; 1-3 parts of seed herb: buying from head stores or collecting, drying and crushing into less than or equal 100 meshes; 1-3 parts of grass or leaf herb: buying from head stores or collecting, drying and crushing into less than or equal 100 meshes; and 0.1-0.5 parts of water soluble antibiotics: buying the ivermectin WP or abamectin WP; (b) mixing the raw material excluding the antibiotics: mixing the raw material according to part by weight; (c) piling and fermenting: piling the mixture into a 0.3-0.8 meter high, 0.8-1.2 meter wide pile, fermenting for 30-45 days at 60-65 degrees C; and (d) drying and adding the antibiotics: spreading out the pile after fermentation, drying until water content reaches 15-20%, adding 0.15 parts of ivermectin WP or abamectin WP, mixing, and packaging for use.