TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The sodium ion source in fifth step is selected from sodium hydroxide, sodium acetate or sodium 2-ethylhexanoate (preferably sodium 2-ethylhexanoate).    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The alcoholic solvent in first step is selected from methanol, ethanol, isopropyl alcohol and/or tertiary butyl alcohol (preferably methanol). The base in first step is an organic base and is selected from triethylamine, pyridine, N-methylpiperidine, 1,8-diazabicycloundecene, 4,4-dimcthylaminopyridine, dicyclohexylamine, diphenylamine, diisopropylamine, N-tert-butylcyclohcxylamine and/or N,N-dibenzylethylenediamine (preferably triethylamine). The organic solvent in second step is n-butyl acetate or ethyl acetate. The acid in fourth step is hydrochloric acid or sulfuric acid (preferably hydrochloric acid). The organic solvent in fifth step is a ketonic solvent or alcoholic solvent. The ketonic solvent is selected from acetone, methyl ethyl ketone, methyl isobutyl ketone, methyl isopropyl ketone and/or methyl tertiary butyl ketone. The alcoholic solvent is selected from methanol, ethanol, isopropyl alcohol and/or tertiary butyl alcohol. Preferred Method: The pH in fourth step is 5-7 (preferably 6-6.3). In the method, all the steps are preferably performed at a temperature -10 degrees C to reflux temperature of the solvent used. ACTIVITY - Antibacterial. No biological data given.    MECHANISM OF ACTION - None given.    EXAMPLE - 7-Amino-3-(((2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio)methyl)-3-cephem-4-carboxylic acid (1 kg) and 2-mercaptobenzothiazole 2-(2-aminothiazol-4-yl)-2-syn-methoxyiminoacetate (1.04 kg) were added in methanol (4.5 l) at 0-5 degrees C and methanol (0.5 l) was flushed into the reactor. The mixture was kept at (-)2-2 degrees C and triethylamine (0.55 kg) was dropwise added under stirring over 30 minutes. The solution was stirred at 0-3 degrees C until the reaction was completed. Subsequently, sodium metabisulfite (0.02 kg), water (6 l) and n-butyl acetate (10 l) were added at 3-7 degrees C. The reaction mixture was stirred for 15-20 minutes and settled at 20-250 degrees C. The aqueous phase was separated and pH was adjusted to 6-6.3 with dilute hydrochloric acid solution. Ethylenediaminetetraacetic acid (0.02 kg) and sodium metabisulfite (0.01 kg) were added to it under stirring at 25-30 degrees C. A solution consisting of sodium 2-ethylhexanoate (1.1 kg) in acetone (5 l) was added to the reaction mixture within 1 hour at 26-30 degrees C under stirring. Afterwards acetone (25 l) was added dropwise and the resulting crystal suspension was stirred further for 1 hour at the same temperature. The material was filtered, washed with acetone (2 l) and dried in a vacuum drying chamber at 40 degrees C for 3 hours to get ceftriaxone disodium hemiheptahydrate (1.65 kg; 92.7 %; 99.79 % chromatographic purity).