TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The nano-structured catalyst comprises a zeolite mineral. The nano-structured catalyst comprises zeolite-X of formula Na2O.Al2O3.2.5SiO2.6H2O where SiO2/Al2O3 is 2-3; zeolite-Y of formula Na2O.Al2O3.4.8SiO2.8.9H2O where SiO2/Al2O3 ranges from 3-6; faujasite-Na of formula 3.5(Ca0.3)3.5(Na0.6)3.5(Mg0.1)Al7Si17O48.32(H2O); hydrotalcite of formula (M(z+)1-xM3+x(OH)2)(q+)(X(n-))q/n.yH2O; magnesium-aluminum hydrotalcite of formula (Mg(1-x')Alx'(OH)2)(x'+)(CO3)x'/n'2-; or titanosilicate ETS-10. The nano-structured catalyst comprises one of sodium carbonate, magnesium carbonate, potassium carbonate or calcium carbonate supported on aluminum; one of sodium hydroxide, magnesium hydroxide, potassium hydroxide or calcium hydroxide supported on aluminum; or zirconium oxysulfate (ZrOSO4), lanthanum oxide (La2O3), magnesium oxide (MgO), mixture of La2O3 and MgO.M2+=Ca2+, Mg2+, Mn2+, Fe2+, Co2+, Ni2+, Cu2+ or Zn2+;q, x and y=2-4;x'=0.25-0.55;n'=2.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The monohydric alcohol comprises methanol and the methanol is present at a critical temperature (Tc) of at least 240 (preferably 240-350) degrees C and a critical pressure (Pc) of at least 1140 (preferably 1200-3500) psig. The nano-structured catalyst is present with a largest cross-sectional dimension of 50-100 nm. The continuous trans-esterification of monohydric alcohol is carried out in a reactor having a flow rate of 1-10 ml/min and the residence time of the triglyceride in the reactor is 5-15 minutes. Preferred Components: The triglyceride is provided from at least one camelina oil, jatropha curcas oil, salicornia oil, palm oil, soybean oil, rapeseed oil, sunflower seed oil, peanut oil, cottonseed oil, palm kernel oil, coconut oil, olive oil, linseed oil, corn oil, canola oil, soybean oil, tall oil, tall oil fatty acids, white grease, poultry fat, white tallow, yellow grease, crude tall oil, or brown grease. The monohydric alcohol is selected from methanol, ethanol, n-propyl alcohol, n-butyl alcohol or n-pentyl alcohol. The triglycerides comprise a fatty acid triglyceride. The fatty acid triglycerides is a compound of formula R1-C(O)O-CH2-CH(O-C(O)-R2)-CH2-OC(O)-R3.R1-R3=acyclic aliphatic hydrocarbon (preferably saturated hydrocarbon, monounsaturated hydrocarbon, or polyunsaturated hydrocarbon). EXAMPLE - No suitable example given.