NOVELTY - Preparation of hydrochloric acid sinomenine injection involves: extracting air, thick orientavine powder in percolation tube, impregnating, percolating, stopping percolation to form diacolation liquid; adding liquid to column of cation exchange resin or 152 type resin and treating with silicotungstic acid test solution to obtain transparent outflow examination deposition solution, detecting by non-alkali spot thin-layer chromatography, soaking the resin, combining eluent, removing salt, and drying to obtain acid crude product; adding active carbon, filtering; and preparing injection.    USE - For preparation of hydrochloric acid sinomenine injection (claimed) used for treating rheumatism and arthroncus, paralysis, pruritus, and as antiarrhythmic for treating arrhythmia and so on; also for treating rheumatic arthritis and rheumatoid arthritis, and for treating ankylosing spondylitis.    ADVANTAGE - The extraction yield is high. The operation is more convenient, reduces organic solvent dosage, does not cause toxicity to the operator and does not cause environmental harm and pollution, reduces the organic solvent treatment process thereby providing environment protection, and reduces the investment cost and is environment-friendly. The purity is high, forms no solvent residue, and reduces the potential harm to human body.    DETAILED DESCRIPTION - Preparation of hydrochloric acid sinomenine injection involves: acid preparation method, where acid is prepared as follows: extracting air, 100 to 1000 parts by weight of orientavine thick powder and 60-1000 parts by volume of 0.1-1 mol/l HCl, wetting for 0.5 to 8 hours, putting it in percolation tube, then adding 0.1-1 mol/l HCl to cover the liquid, impregnating for 6-48 hours, percolating at a speed of 5 ml/minute for 6 to 24 hours, stopping percolation to obtain diacolation liquid for further use; adding the percolation processed liquid to a column of cation exchange resin or 152 type resin, where diameter-height ratio of column is 8-12 V, the sampling speed is 2-5 fold of column volume/hour, and treating with silicotungstic acid test solution to obtain a transparent outflow examination deposition solution, detecting by non-alkali spot thin-layer chromatography detecting method, stopping, soaking resin or 152 type resin for 12 hours at 3-10 degrees C with hydrochloric acid solution, eluting 8-15% of ammonia solution and ammonia water with purified water of pH 8-11 until the eluting liquid has no color using ethanol solution or eluting 152 type resin using 3-10% hydrochloric acid solution, where the eluting speed is 2-5 BV/hour, depositing silicon tungstate test solution, receiving the eluent with silicotungstic acid test solution, stopping detection when no deposition is observed, combining the eluent, neutralizing to pH of 6-8 by hydrochloric acid or ammonia water, removing salt, concentrating and drying to obtain acid crude product, refining by taking 5 to 10 parts by weight of crude acid, until it is completely dissolved by 30-120 parts by volume of 10 95% ethanol or purified water, heating and refluxing, adding active carbon in 3-6 times amount, keeping the temperature to reflow for 10 to 30 minutes, filtering, concentrating the filtrate, cooling, crystallizing, filtering, using 75-95% of alcohol to wash filter cake until the filtrate is colorless to obtain hydrochloric acid sinomenine, where the raw material for forming injection is 15-35 parts by weight of acid, 0.1 to 3 parts by weight of sodium bisulfite, and 0.1 to 3 parts by weight of versene disodium; for preparing the injection, adding acid to water, stirring, charging nitrogen, dissolving, and then adding sodium bisulfite and versene disodium, stirring to dissolve, continuously charging nitrogen, adding 0.01 to 0.20% of active carbon at 35 to 45 degrees C for 5 to 15 minutes, filtering to remove carbon, supplementing water for injection to 1000 parts by volume, detecting, fine filtering, charging nitrogen, filling and sealing at 100-120 degrees C for 20 to 40 minutes to obtain the finished product.