TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Process: The step (a) comprises: (i) charging toluene into the flask; (ii) charging benzophenone and stirring for 15 minutes; (iii) charging sodium methoxide and stirring for 15 minutes; (iv) cooling reaction mass to -10 degrees C to -5 degrees C; (v) slowly adding methyl chloroacetate at the same temperature; (vi) maintaining reaction mass at -10 degrees C to -5 degrees C for 1 hour; (vii) charging water and stirring for 30 minutes; (viii) separating organic layer and washing with demineralized (DM) water; (ix) distilling toluene completely under vacuum; and (x) taking (II) to next stage. The step (b) comprises: (ia) charging methanol to (II) and stirring for 30 minutes; (iia) dissolving p-toluene sulfonic acid monohydrate in methanol and adding slowly at 25-55 degrees C; (iiia) bringing reaction mass to room temperature and maintaining for 1 hour; (iva) cooling reaction mass to 0-5 degrees C and maintaining at the same temperature for 2 hours; (va) filtering and washing with methanol; (via) dissolving wet compound in ethyl acetate and washing with 5% of sodium bicarbonate solution; (viia) distilling off completely under vacuum; (viiia) bringing residue to room temperature and charging n-hexane; (ixa) maintaining under stirring at room temperature for 2 hours; and (xa) filtering and washing with n-hexane to yield (III). The step (c) comprises: (ib) charging purified water into flask; (iib) charging (III) and stirring for 10 minutes; (iiib) charging 1N sodium hydroxide solution and stirring for 15 minutes; (ivb) heating reaction mass to 90-95 degrees C; (vb) maintaining 1 hour at the same temperature; (vib) adjusting reaction mass pH to 2-3 with 1N hydrochloric acid; (viib) cooling reaction mass to 5-10 degrees C; (viiib) maintaining reaction mass at the same temperature for 2 hours; and (ixb) filtering to yield (IV). The step (d) comprises: (ic) charging methyl tert-butyl ether (MTB) and acetone into flask; (iic) charging (IV) and stirring for 15 minutes; (iiic) heating reaction mass to reflux temperature (55 degrees C); (ivc) dissolving (S)-(-)p-nitro phenyl ethyl amine in MTB and adding slowly during 30 minutes at reflux temperature; (vc) maintaining reaction mass under reflux temperature for 1 hour; (vic) bringing reaction mass slowly to room temperature during 2 hours; (viic) cooling reaction mass to 10-15 degrees C; (viiic) maintaining reaction mass at the same temperature for 12 hours; (ixc) filtering and washing with MTB; (xc) suspending wet salt in a mixture of DM water and MTB; (xic) acidifying reaction mass with concentrated hydrochloric acid; (xiic) stirring reaction mass for 30 minutes and separating two clear layers; (xiiic) extracting aqueous layer with MTB and combining organic layers; (xivc) washing MTB layer with water and drying over sodium sulfate; (xvc) distilling off MTB completely and charging MTB and n-heptane to the residue at 40 degrees C; (xvic) bringing residue to room temperature; (xviic) stirring at room temperature for 2-3 hours; and (xviiic) filtering and washing with n-heptane to yield (I). Preferred Components: (I) has solid state characteristics as given in figure 1-3 of the specification. ACTIVITY - Hypotensive; Respiratory-Gen.    MECHANISM OF ACTION - None given.    EXAMPLE - 2-Hydroxy-3-methoxy-3,3-diphenyl propionic acid (200 g) was added to a mixture of methyl tert-butyl ether (MTB) (1.25 l) and acetone (1.5 l) into a round bottomed flask (3 l). The reaction mass was heated to reflux temperature of 50-55 degrees C and (S)-(-)p-nitro phenyl ethyl amine (61 g dissolved in MTB (250 ml)) was added slowly during 30 minutes at reflux temperature. The reaction mass was maintained at the same temperature for 1 hour and cooled to 10-15 degrees C and maintained at the same temperature for 12 hours. The obtained reaction mixture was filtered and washed with MTB (500 ml). The wet diastereomeric salt was suspended in a mixture of MTB (500 ml) and water (1.5 l) and acidified with concentrated hydrochloric acid (30 ml). The resulting mixture was stirred for 30 minutes and the organic layer was separated. Aqueous layer was extracted with MTB (500 ml) and the combined MTB layer was washed with water and distilled completely under vacuum. The reaction mass was brought to 40 degrees C and mixture of MTB (138 ml) and n-heptane (322 ml) were charged and cooled to 25-30 degrees C to afford S-2-hydroxy-3-methoxy-3,3-diphenyl propionic acid (55 g).