TECHNOLOGY FOCUS - INSTRUMENTATION AND TESTING - Preferred Components: The mixer includes a mixing device rotating within the mixer at a speed of 400-4000 revolutions per minute (rpm). In the method (m2), the first reactor is an inverted conical vessel having an open bottom and the second reactor is immediately below the first reactor and is a cylindrical vessel having an open top connected to the open bottom of the first reactor, where the transferring of the liquid material includes the material moving down through the open bottom and into the open top. The enzyme injection apparatus injects the first portion of the enzyme solution at several of locations along a longitudinal length of the screw of the second screw conveyor. The second reactor includes second reactors each receiving the slurry being transferred from the first reactor. In the system (s1), the first reactor includes an open bottom, and the second reactor is immediately below the first reactor and is a cylindrical vessel having an open top connected to the open bottom of the first reactor, where the transferring of the liquid material includes the material moving down through the open bottom and into the open top. The system (s1) further comprises a buffer tank temporarily retaining the slurry from the second conveyor and discharging the slurry to the positive displacement pump. The inlets for enzyme injection are equally spaced at several of locations along a longitudinal length of a screw of the second screw conveyor.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The slurry is a liquid material when discharged from the first reactor vessel and the method (m1) further involves transferring the liquefied slurry to a second reactor vessel for further enzymatic hydrolysis, where the first reactor vessel has a inverted conical shape and the second reactor vessel has a cylindrical shape. In the method (m1), the temperature of the slurry is maintained at 45-55 degrees C from the addition of the first portion of the enzyme solution to at least discharge from the first or second reactor vessel. In the method (m1), the first reactor includes an upper inlet receiving the slurry with enzyme solution, an upper portion having an expanding cross-sectional area containing rotating arms of an internal rotating mixer, where the arms become progressively longer in a downward direction through the upper portion. The slurry with the alkali material in the first conveyor has an average pH of 4.5-6.5, an average temperature of 45-55 degrees C, and a consistency of 10-35 wt.% where the wt.% is a ratio of insoluble particles in the mixture and the total weight of the mixture. The enzyme solution is added to the slurry at several of locations within the second conveyor. The slurry is retained in the mixing only for a period of 0.05-200 seconds. The method (m2) further involves temporarily retaining the slurry from the second conveyor in a buffer tank and pumping the slurry from the buffer tank by the positive displacement pump to the mixer. The mixing in the first screw conveyor cools and increases the pH of the slurry as compared to the conditions of the slurry entering the first screw conveyor. EXAMPLE - No suitable example given.