TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Method: In extracting target compounds from the biomass, percolating the solvent through the agglomerated particles includes applying the solvent in accordance with counter-current leach extraction. Drying the biomass includes drying the microbial biomass at a temperature of 85 degrees C or greater than 148.5 degrees C or lower. The method further comprises adjusting ambient pressure while agglomerating the fines in order to advance dehydration of the biomass; exposing the agglomerated particle to a nonflammable solvent to create a non-flammable mixture; drying the agglomerated particles at atmospheric pressure at a temperature ranging from 85 degrees F up to 150 degrees F; and drying the agglomerated particles at a pressure that is less than atmospheric, where drying the agglomerated particles at the pressure that is less than atmospheric includes lowering the temperature of the agglomerated particles. The biomass is derived from a suspension culture that includes one or more of the following: a microbial biomass of algae, bacteria, yeast, fungi, and other microorganism, suspended solids in water and wastewater particulates. The method as well comprises applying the agglomerated particles to a separation column with a high length-to-diameter ratio of 5:1 or greater to 30:1. The solvent is a first solvent that extracts a first target compound, and where the method further comprises introducing at least a second solvent to the column to extract a second target compound. Agglomerating the fines to create agglomerated particles includes rotating the fines while applying an insoluble binding agent. Agglomerating the particles includes adding only coarse water droplets to agglomerate the particles. Percolating the solvent occurs at or below 35 degrees C. In generating the prill, the step of agglomerating the particles occurs at a sub- atmospheric pressure, where the step of agglomerating the particles includes using a polymeric binder. Agglomerating dried and ground biomass from the suspension culture further comprises, exposing the at least partially dried and ground biomass before, during or after agglomeration to at least one of the following sources of heat, air, light, microwave, visible light, infrared, other electromagnetic radiation or other energy source where the at least partially dried and ground biomass are further dehydrated by the at least one source; and adjusting ambient pressure while agglomerating the dried and ground biomass in order to advance dehydration of the biomass. The cultures are exposed to a gas and optionally, where the gas is a non-flammable gas; and where the agglomerated particles form a nonflammable mixture with the gas. The agglomerated particles are further exposed to a solvent and products of the agglomerated particles are extracted. The product is lipids, where the product is a fuel or feedstock to produce fuel. The pressure is atmospheric and temperature is 85 degrees F or greater but less than 150 degrees F. The cultures are spray-dried. The suspension culture comprises algae, bacteria, yeast, fungi, suspended solids in water or wastewater particulates. The method also comprises using a binding agent, where the binding agents comprise corn starch, alginates, glucose, sucrose, fructose or other sugars, lignins and carbohydrates. The agglomerated particles are applied to a separation column with a high length-to-diameter ratio. Preferred Composition: In the prill composition, the agglomerated fines include an insoluble binding agent. The set of agglomerated fines form agglomerated particles each about 300 microns or greater, and where the agglomerated particles comprise 50 percent or more of the prill. The set of agglomerated fines form agglomerated particles each about 300 microns or greater, and where the agglomerated particles comprise 80 percent or more of the prill. Preferred Process: In extracting one or more target compounds from biomass from the suspension culture, a first agent or solvent is introduced to the column to extract a target compound, and sometime later at least a second agent or solvent is introduced to the column to extract a second target compound. The agents comprise hexane, ethanol, chloroform or other solvents or polar agents. Preferred Kit: The kit further comprises one or more solvents. EXAMPLE - No suitable example given.