TECHNOLOGY FOCUS - POLYMERS - Preparation (Claimed): Preparation of (I) comprises (a) dissolving crude dexamethasone palmitate in 5-20 times weight of organic solvent, adding active carbon (0.2-0.5%) to the solution at 30-50 degrees C for 15-30 minutes, filtering decarburization, and collecting the filtrate, where the organic solvent is acetonitrile, methanol, ethanol, isopropanol (preferred) and dimethyl acetamide, (b) cooling the filtrate at room temperature, slowly adding purified water, stirring to deposit, allowing to stand for 4 hours, filtering and collecting the precipitate, and (c) dissolving the sediment by ethanol/ethyl acetate (1:1), mixing the sediment to macro-porous absorption resin, stirring the resin, eluting with water, ethanol (10%), alcohol (40%), concentrating via reducing pressure, and drying to obtain the refined dexamethasone palmitate. Preferred Components: The macro-porous adsorption resin is styrene-type macroporous absorbing resin, where the styrene-type macro-porous absorbing resin is Amberlite XAD-1 (RTM: Styrene-divinyl benzene copolymers), Sepabeads SP825 (RTM: Aromatic synthetic resin adsorbents), Amberlite XAD-4 (RTM: styrene-divinyl benzene copolymers), HPD300, H103, or SIP-1100 macro-porous absorbing resin. Preferred Method: The total volume of the solution added in the step (a) is 0.3-0.4% (g/ml) of active carbon at 40 degrees C for 15-30 minutes. ACTIVITY - Antirheumatic; Antiarthritic.    MECHANISM OF ACTION - Epidermal growth factor receptor inhibitor.    ADMINISTRATION - Administration of (I) is topical and intravenous. No dosage details given.    EXAMPLE - Crude dexamethasone palmitate (10 g) was dissolved in alcohol (50 ml). Active carbon (10 g) was added to solution and stirred at 40 degrees C for 15 minutes, filtered for decarburization, and then filtrate was cooled at room temperature. Purified water was added to the filtrate, stirred, allowed to stand for 1 hour, filtered, and then precipitate was collected. The precipitate was dissolved in 1:1 of ethanol/ethyl acetate (20 ml), and then added with Sepabeads SP825 (RTM: Aromatic synthetic resin adsorbents) macro-porous absorption resin (40 g), stirred, eluted by alcohol (40%), ethanol (10%), concentrated via reduced pressure, and dried to obtain refined dexamethasone palmitate (Yield: 97.7%).