NOVELTY - Deprotection preparation of dimethoxy taxane compound involves activating silica gel with acid methanol solution; dissolving acid-activated silica gel in organic solvent; adding compounds 3-tert-butoxycarbonyl-2-p-methoxyphenyl-4-phenyl-(2R,4S,5R)-1,3-oxazoldine-5-carboxylate-4 alpha -acetoxy-2 alpha -benzyloxy-5 beta , and 20-epoxy-1 beta -hydroxy-9-oxo-7 beta ,10 beta -dimethoxy-11-aplotaxene-13 alpha ester, performing deprotection reaction at - 20 to 100 degrees C for 15-48 minutes, and filtering reaction liquid; and concentrating filtered liquid till dry, and sending through silica gel chromatographic column for extraction.    USE - Method for deprotection preparation of dimethoxy taxane compound (claimed).    ADVANTAGE - The method allows the protecting group to be removed in acidic condition. It has simple operation and is suitable for industrial production. There is no by-product produced in the reaction process, and the reaction yield and the purity of the product are increased. Further, the filtered acid-activated silica gel can be recycled.    DETAILED DESCRIPTION - Deprotection preparation of dimethoxy taxane compound comprises:    (A) dissolving acid into methanol to prepare methanol solution comprising 0.01-100 mol/l acid, and adding 100-800 mesh silica gel, uniformly stirring at room temperature for 1-3 hours, and rotationally steaming till dry to obtain acid-activated silica gel, where mass ratio of acid to silica gel is 1:100-100:1;    (B) dissolving acid-activated silica gel in organic solvent, where mass ratio of acid-activated silica gel to organic solvent is 1:100-100:1;    (C) adding compounds 3-tert-butoxycarbonyl-2-p-methoxyphenyl-4-phenyl-(2R,4S,5R)-1,3-oxazoldine-5-carboxylate-4 alpha -acetoxy-2 alpha -benzyloxy-5 beta , and 20-epoxy-1 beta -hydroxy-9-oxo-7 beta ,10 beta -dimethoxy-11-aplotaxene-13 alpha ester, where mass ratio of acid-activated silica gel to compounds is 1:100-10:1;    (D) continuously stirring and performing deprotection reaction at - 20 to 100 degrees C for 15-48 minutes, and then ending the reaction;    (E) extracting and filtering the obtained reaction liquid to obtain filtered liquid and acid-activated silica gel; and    (F) concentrating the filtered liquid till dry, and sending through silica gel chromatographic column for extraction to obtain the product dimethoxy taxane compound which is 4 alpha -acetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1 beta -hydroxy-7 beta ,10 beta -dimethoxy-9-oxotaxol-11-alkene-13 alpha -yl-(2R,3S)-3-tertbutoxycarbonyl amino-2-hydroxy-3-phenylpropionate.