NOVELTY - Drug composition containing dehydrogenated corydaline, is prepared using dehydrogenated alkali and total alkali of Corydalis ochotensis which is obtained by extracting the C.ochotensis using ethanol hot reflux extraction and subjecting the extract to quaternary ammonium alkali adsorption, where the alkali is dehydrogenated tetrahydropalmatine, palmatine, tetrandrine or 13-methyl dehydrogenated benzydamine alkali.    USE - The composition is useful for treating myocardial infarction.    ADVANTAGE - The method is simple, rapid, safe, and hence environmentally-friendly, cost-effective and suitable for large scale production, and produces the product with high yield. The composition prolongs mouse hypoxia tolerance time.    DETAILED DESCRIPTION - Drug composition containing dehydrogenated corydaline, is prepared using dehydrogenated alkali and total alkali of Corydalis ochotensis which is obtained by extracting the C.ochotensis using ethanol hot reflux extraction and subjecting the extract to quaternary ammonium alkali adsorption, where the alkali is dehydrogenated tetrahydropalmatine, palmatine, tetrandrine or 13-methyl dehydrogenated benzydamine alkali. The content of the alkali in C.ochotensis is not less than 10%, when subjected to high performance liquid chromatography, and quaternary ammonium total alkali content is not less than 50%. INDEPENDENT CLAIMS are included for the following:    (1) method (M1) for preparing the composition, involves selecting rhizoma corydalis medicine material, crushing the materials, adding 12-16 times of 80% ethanol to the crushed material, extracting the material for 3 times for 3-5 hours, combining the extraction solutions, filtering the extract, recovering ethanol from the filtrate, passing the filtrate through X-5 type macroporous adsorption resin, where flow speed is 1-3/minute, eluting the fractions using 50% ethanol, washing the impurities, collecting the fractions, decompressing and concentrating the fractions, vacuum drying the concentrate below 60 degrees C, dissolving the dried product using 95% of ethanol, filtering the product, and recovering solvent; and    (2) method (M2) for measuring homocysteine consistency, involves performing UV colorimetric method, where UV colorimetric method involves by preparing reference product solution by obtaining dehydrogenation fumitory alkali, and dissolving alkali using methanol to obtain 0.1 mg reference substance solution, preparing test sample solution by obtaining predetermined concentration of the composition, and ultrasonically dissolving the composition using 80% of methanol to prepare 0.1 g/ml test sample solution, absorbing 0.5 ml of reference substance solution and test solution, adding phosphate buffer solution having pH of 8, 5 ml of bromine thymol blue vanillin test solution, and 6 ml of chloroform, shaking the solution, transferring the solution into a separating funnel, adding 1 g of anhydrous sodium sulfate, separating chloroform layer, and measuring the absorbance at 415 nm.