NOVELTY - Increasing content of S-adenosyl-L-methionine (SAM) and superoxide dismutase (SOD) in Sorghum fuel alcohol waste Saccharomyces cerevisiae comprises (A) fermenting Saccharomyces cerevisiae and sorghum stalk juice; (B) preparing activated fermentation liquor; (C) preparing activated wet waste yeast thallus; and (D) extracting and centrifuging. The step comprises (A) fermenting S. cerevisiae and Sorghum stalk juice to obtain fuel alcohol; and centrifuging waste S. cerevisiae liquid at 3000-5000 revolutions/minute (rpm).    USE - Method for increasing content of S-adenosyl-L-methionine and superoxide dismutase in Sorghum fuel alcohol waste Saccharomyces cerevisiae (claimed).    ADVANTAGE - The method lowers cost of yeast.    DETAILED DESCRIPTION - Increasing content of S-adenosyl-L-methionine (SAM) and superoxide dismutase (SOD) in Sorghum fuel alcohol waste S. cerevisiae comprises (A) fermenting Saccharomyces cerevisiae and sorghum stalk juice; (B) preparing activated fermentation liquor; (C) preparing activated wet waste yeast thallus; and (D) extracting and centrifuging. The step comprises (A) fermenting S. cerevisiae and Sorghum stalk juice for 20-38 hours to obtain fuel alcohol; and centrifuging waste S. cerevisiae liquid at 3000-5000 revolutions/minute (rpm) for 5-15 minutes to obtain wet waste yeast thallus. The step (B) comprises adding wet waste yeast thallus (40-60 g), glucose (20-50 g), methionine (0.5-4 g), copper sulfate (0.005-0.015 g) and zinc sulfate (0.03-0.06 g) to fresh squeezed Sorghum stalk juice (13-20% of total sugar) until volume is 1 L and uniformly mixing; and performing activated cultivation at pH of 5, air quantity of 0.8-1.5 volume of air/volume of liquid/minute (vvm), stirring speed of 120-160 rpm and temperature of 30-34 degrees C for 20-40 hours obtain activated fermentation liquor. The step (C) comprises centrifuging activated fermentation liquor at 3000-5000 rpm for 5-15 minutes for removing liquid supernatant to obtain activated wet waste yeast thallus. The step (D) comprises (i) adding activated wet waste yeast thallus to 6-12 times 1.5 mol/L perchloric acid solution and stirring under ice bath at 3000-5000 rpm for 1-2 hours, centrifuging for 5-15 minutes and separating to obtain SAM liquid supernatant; or (ii) adding activated wet waste yeast thallus to 8-10 times 70-90% isopropanol solution and stirring under ice bath for 1-2 hours at 4000-6000 rpm, centrifuging for 5-15 minutes and removing liquid supernatant to obtain precipitate; and adding 2-4 times 0.05 mol/L dipotassium hydrogen phosphate-potassium dihydrogen phosphate buffer solution (pH is 7.8), stirring and extracting for 1-3 hours, and centrifuging at 4000-6000 rpm for 5-15 minutes to obtain SOD liquid supernatant.