TECHNOLOGY FOCUS - BIOTECHNOLOGY - Preferred Host: In the host, the host has been made deficient of one or more of: (A) a gene encoding fatty acyl-CoA reductase (EC1.2.1.n2), gene ACIAD 3383 (SEQ ID NO: 1) or a functional equivalent in an Acinetobacter host, and/or one or more of (B) a gene encoding diacylglycerol kinase (EC:2.7.1.107), gene ACIAD 2837 (fully defined 396 bp (SEQ ID NO: 5)) or a functional equivalent in an Acinetobacter host; a gene encoding succinate dehydrogenase (EC:1.3.5.1), gene ACIAD 2880 (fully defined 1899 bp (SEQ ID NO: 6)) or a functional equivalent in an Acinetobacter host; a gene encoding glycerol-3-phosphate dehydrogenase (EC 1.1.5.3), gene ACIAD 2844 (fully defined 1524 bp (SEQ ID NO: 7)) or a functional equivalent in an Acinetobacter host, a gene encoding cytochrome o ubiquinol oxidase subunit II (EC:1.10.3.-), gene ACIAD 2425 (fully defined 1062 bp (SEQ ID NO: 8)) or a functional equivalent in an Acinetobacter host; a gene encoding cytochrome o ubiquinol oxidase subunit I (EC:1.10.3.-), gene ACIAD 2426 (fully defined 1989 (SEQ ID NO: 9)), or a functional equivalent in an Acinetobacter host; a gene encoding cytochrome d terminal oxidase polypeptide subunit II (EC1.10.3.-), gene ACIAD 2291 (fully defined 1146 bp (SEQ ID NO: 10)), or a functional equivalent in an Acinetobacter host; a gene encoding pyruvate dehydrogenase (EC:1.2.2.2), gene ACIAD 3381 (SEQ ID NO: 3), or a functional equivalent in an Acinetobacter host; a gene encoding carboxylesterase (EC:3.1.1.1), gene ACIAD 3648 (fully defined 1071 bp (SEQ ID NO: 11)), or a functional equivalent in an Acinetobacter host; a gene encoding esterase, gene ACIAD 1134 (fully defined 885 bp (SEQ ID NO: 12)), or a functional equivalent in an Acinetobacter host; a gene encoding lipase (EC:3.1.1.3), gene ACIAD 3309 (SEQ ID NO: 2) or a functional equivalent in an Acinetobacter host, gene ACIAD 1121 (fully defined 972 bp (SEQ ID NO: 13)) or a functional equivalent in an Acinetobacter host; a gene encoding acyl-CoA synthetase (EC:6.2.1.3), gene ACIAD 0235 (fully defined 1680 bp (SEQ ID NO: 14)) or a functional equivalent in an Acinetobacter host; or gene ACIAD 2177 (SEQ ID NO: 4) or a functional equivalent in an Acinetobacter host, where the host is capable of increased production of TAGs, wax esters and/or total lipids compared to the parent host. The host has been made deficient of one or more of: (A) a gene encoding fatty acyl-CoA reductase (EC1.2.1.n2), gene ACIAD 3383 (SEQ ID NO: 1) or a functional equivalent in an Acinetobacter host, and/or one or more of (B) a gene encoding cytochrome o ubiquinol oxidase subunit II (EC:1.10.3.-), gene ACIAD 2425 (SEQ ID NO: 8) or a functional equivalent in an Acinetobacter host, or a gene encoding succinate dehydrogenase (EC:1.3.5.1), gene ACIAD 2880 (SEQ ID NO: 6), or a functional equivalent in an Acinetobacter host, where the host is capable of increased production of TAGs, wax esters and/or of total lipids compared to the parent host. The host has been made deficient of one or more of a gene encoding lipase (EC:3.1.1.3), gene ACIAD 3309 (SEQ ID NO: 2) or a functional equivalent in an Acinetobacter host, a gene encoding pyruvate dehydrogenase (EC:1.2.2.2), gene ACIAD 3381 (SEQ ID NO: 3) or a functional equivalent in an Acinetobacter host and/or gene 2177 or a functional equivalent in an Acinetobacter host, where the host is capable of increased production of wax esters and/or total lipids. The host has been made deficient of a gene encoding lipase (EC:3.1.1.3), gene ACIAD 3309 (SEQ ID NO: 2) or a functional equivalent in an Acinetobacter host, alone or together with one or more of a gene encoding diacylglycerol kinase (EC:2.7.1.107), gene ACIAD 2837 (SEQ ID NO: 5) or a functional equivalent in an Acinetobacter host; a gene encoding fatty acyl-CoA reductase (EC1.2.1.n2), gene ACIAD 3383 (SEQ ID NO: 1), or a functional equivalent in an Acinetobacter host; a gene encoding succinate dehydrogenase (EC:1.3.5.1), gene ACIAD 2880 (SEQ ID NO: 6) or a functional equivalent in an Acinetobacter host; a gene encoding glycerol-3-phosphate dehydrogenase (EC 1.1.5.3), gene ACIAD 2844 (SEQ ID NO: 7) or a functional equivalent in an Acinetobacter host; a gene encoding cytochrome o ubiquinol oxidase subunit II (EC:1.10.3.-), gene ACIAD 2425 (SEQ ID NO: 8) or a functional equivalent in an Acinetobacter host; a gene encoding cytochrome o ubiquinol oxidase subunit I (EC:1.10.3.-), gene ACIAD 2426 (SEQ ID NO: 9), or a functional equivalent in an Acinetobacter host; a gene encoding cytochrome d terminal oxidase polypeptide subunit II (EC1.10.3.-), gene ACIAD 2291 (SEQ ID NO: 10), or a functional equivalent in an Acinetobacter host; a gene encoding pyruvate dehydrogenase (EC1.2.2.2), gene ACIAD 3381 (SEQ ID NO: 3) or a functional equivalent in an Acinetobacter host, a gene encoding carboxylesterase (EC:3.1.1.1), gene ACIAD 3648 (SEQ ID NO: 11), or a functional equivalent in an Acinetobacter host, a gene encoding esterase, gene ACIAD 1134 (SEQ ID NO: 12), or a functional equivalent in an Acinetobacter host, various lipases (EC:3.1.1.3), gene ACIAD 1121 (SEQ ID NO: 13) or a functional equivalent in an Acinetobacter host, or a gene encoding acyl-CoA synthetase (EC:6.2.1.3), gene ACIAD 0235 (SEQ ID NO: 14) or a functional equivalent in an Acinetobacter host, where the host is capable of increased production of wax esters and/or of total lipids. The host has been made deficient of a gene encoding pyruvate dehydrogenase (EC:1.2.2.2), gene ACIAD 3381 (SEQ ID NO: 3) or a functional equivalent in an Acinetobacter host, alone or together with one or more of the genes. The host has been made deficient of gene ACIAD 2177 or a functional equivalent in an Acinetobacter host alone or together with one or more of the genes above, where the host is capable of increased production of total lipids. The host been genetically modified to express one or more genes encoding the enzymes of lipid biosynthesis pathway. The host been genetically modified to express a gene encoding diacylglycerol synthase enzyme (EC 2.3.1.20) or to express a gene encoding WS and/or DGAT (EC 2.3.1.75 and EC 2.3.1.20). The host is genetically modified to express a gene selected from: (a) sco0958 (fully defined 1341 bp (SEQ ID NO: 29)) or aftA (fully defined 1377 bp (SEQ ID NO: 31)); (b) a functional equivalent of sco0958 in a Streptomyces species, the functional equivalent encoding diacylglycerol synthase enzyme (EC 2.3.1.20) or a functional equivalent of aftA in an Acinetobacter species, the functional equivalent encoding WS and/or DGAT (EC 2.3.1.75 and EC 2.3.1.20); (c) a nucleotide sequence which hybridizes to SEQ ID NO: 29 under stringent hybridization conditions and encodes diacylglycerol synthase enzyme (EC 2.3.1.20) activity or a nucleotide sequence which hybridizes to SEQ ID NO: 31 under stringent hybridization conditions and encodes WS and/or DGAT (EC 2.3.1.75 and EC 2.3.1.20); and (d) a nucleotide sequence encoding fully defined 446 amino acids (SEQ ID NO: 30), or a sequence having at least 60% identity to the sequence and having diacylglycerol synthase enzyme activity (EC 2.3.1.20), or a nucleotide sequence encoding fully defined 458 amino acids (SEQ ID NO: 32) or a sequence having at least 60% identity to the sequence and having wax ester synthase (WS) and/or diacylglycerol acyltransferase (DGAT) (EC 2.3.1.75 and EC 2.3.1.20) activity. Preferred Method: In genetically modifying the Acinetobacter host, the introduced gene is sco958 and/or aftA, or where gene AftA is overexpressed. EXAMPLE - No suitable example given.