TECHNOLOGY FOCUS - BIOLOGY - Preferred Method: The co-culturing involves exposing the photosynthetic microorganisms to light. The non-photosynthetic microorganisms are genetically modified to increase biofuel production. The diatoms are gown with a source of silica. The algae comprise diatoms comprising frustules, where the non-photosynthetic microorganisms are immobilized on the frustules. The step of co-culturing is performed in a bioreactor or in an open environment. The open environment is selected from natural waters (e.g. lakes, lagoons or ponds) or artificial ponds. The bioreactor comprises plastic (e.g. polypropylene or an equivalent alternative), steel or glass. The artificial pond is a raceway pond and may have soft sides or hard sides. The method (M1) further involves isolating the biofuel produced by the non-photosynthetic microorganism from the co-culture. In the method (M2), the solvent is 4-10C alcohol (preferably butanol); and the microorganisms are co-cultured with an external source of carbon. The method (M2) further involves liquid-liquid separation of the lipid produced by the photosynthetic microorganism from a medium in which the microorganisms are co-cultured. Preferred Culture: The co-culture (C2) further comprises an external source of carbon on which the non-photosynthetic microorganisms can grow. Preferred Components: The photosynthetic microorganisms comprise algae or cyanobacteria. The non-photosynthetic microorganisms are fermentative, and comprise bacteria, fungi or yeast. The bacteria is selected from Agrobacterium, Alicyclobacillus, Anabaena, Anacystis, Arthrobacter, Azobacter, Bacillus, Brevibacterium, Chromatium, Clostridium, Corynebacterium, Enterobacter, Erwinia, Escherichia, Lactobacillus, Lactococcus, Mesorhizobium, Methylobacterium, Microbacterium, Phormidium, Pseudomonas, Rhodobacter, Rhodopseudomonas, Rhodospirillum, Rhodococcus, Salmonella, Scenedesmun, Serratia, Shigella, Staphlococcus, Strepromyces, Synnecoccus, or Zymomonas (preferably Clostridium). The fungi is selected from Aspergillus, Candida, Chlamydomonas, Chrysosporium, Cryotococcus, Fusarium, Kluyveromyces, Neotyphodium, Neurospora, Penicillium, Pichia, Saccharomyces, Trichoderma and Xanthophyllomyces. The algae comprise diatoms selected from Coscinodiscophyceae, Fragilariophyceae or Bacillariophyceae. The photosynthetic microorganisms are selected from Botryococcus braunii, Chlorella, Dunaliella tertiolecta, Gracilaria, Pleurochrysis carterae, Sargassum or Ulva.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Composition: The composition (C3) further comprises an oxygenation agent, remnants of algae, and remnants of cyanobacteria. Preferred Components: In the composition (C3), the alcohol comprises butanol. EXAMPLE - No suitable example given.