TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Process: The process further comprises: (a) reacting N-((2R,6R,11R,12R,14aS,15S,20S,23S,25aR)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-1)(1,4,7,10,13,16)hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide compound of formula (II) with thiol compound of formula (HS-R1) to obtain (III); (b) reducing (III) to obtain (I); and (c) reacting N-(20-(3-amino-1-hydroxypropyl)-23-(1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-(1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-1)(1,4,7,10,13,16)hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide compound of formula (IV) with the thiol compound of HS-R1 to obtain (I), where the reducing step is carried out using borane complex or a metal boride. In the process the reaction with 1,2-diaminoethane is carried out using neat 1,2-diaminoethane or 1,2-diaminoethane dissolved in a solvent, where the solvent is water, methanol, ethanol, tetrahydrofuran, isopropanol, trifluoroethanol, acetonitrile or dichloromethane. Preferred Components: The metal boride is zirconium tetra chloride/sodium borohydride or titanium tetra chloride/sodium borohydride. The borane complex is either a borane forming a complex with dimethylsulfide, dibenzylsulfide, diphenylsulfide, tetrahydrofuran or 1,4-oxathiane, or chloroborane forming a complex with dimethyl sulfide. ACTIVITY - Fungicide.    MECHANISM OF ACTION - None given.    EXAMPLE - Methyl 2-((2R,6R,11R,14aS,15S,20S,23S,25aR)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-9-(10,12-dimethyltetradecanamido)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-l)(1,4,7,10,13,16)hexaazacyclohenicosin-12-ylthio)acetate compound (5 g), was suspended in 1,2-diaminoethane (21.12 ml), and the solution was stirred at room temperature for 2 hours. After completion of the reaction, the reaction solution was added to methanol (50 ml), and a solution of acetic acid (46.5 ml) in purified water (115 ml) was added dropwise to it at less than or equal to 20 degrees C. Purified water (375 ml) was added to the resultant mixture, and the solution was washed three times with n-heptane (100 ml), and the aqueous layer was injected into the top of a medium pressure column packed with RP-C18 adsorbent (300 g). After the injection, the column was eluted with 3000 ml of acetonitrile/0.15% acetic acid aqueous solution (1:4 vol/vol), and then the active fractions having a purity of not less than 90% were combined with each other and freeze-dried, to obtain caspofungin acetate.