NOVELTY - Method (I) for isolating components of lignocellulosic material comprises: (a) comminuting lignocellulosic material to form comminuted lignocellulosic material; (b) enzymatically digesting a mixture comprising the comminuted lignocellulosic material, at least one blend of enzymes and aqueous solution, for enzymatic hydrolysis liberating at least one 6C and/or 5C sugar from an insoluble portion of the lignocellulosic material comprising lignin; and (c) separating at least a portion of the aqueous solution containing the 6C and/or 5C sugar from the insoluble portion.    USE - The method is useful in isolating components of lignocellulosic material, where the lignocellulosic material comprises cotton seed hulls (preferred), grain hulls, sugarcane bagasse, corn stover, corn cobs, straw, switchgrass, leaves, stalks, plant shells, softwood pieces, hardwood pieces, sawdust, papermill pulp, waste paper and/or recycled paper, and the components include lignin and 6C and/or 5C sugars (all claimed) e.g. glucose, mannose, galactose, gulose, idose, talose, allose, altrose, psicose, fructose, sorbose, tagatose, xylose, arabinose, ribose, lyxose, ribulose and xylulose.    ADVANTAGE - The method: provides at least 90% yield of lignin and at least 90% or at least 50% yield of the 6C and/or 5C sugars; provides increased product purity and reduced process energy requirements and product modifications and contamination; and does not require high temperature processing, ionization irradiation processing, strong acids, strong alkaline agents, chelating agents, recombinant DNA and/or live anaerobic microorganism cultures.    DETAILED DESCRIPTION - Method (I) for isolating components of lignocellulosic material comprises: (a) comminuting lignocellulosic material to form comminuted lignocellulosic material; (b) enzymatically digesting a mixture comprising the comminuted lignocellulosic material, at least one blend of enzymes and aqueous solution in the absence of any prior non-enzymatic lignin separation from the lignocellulosic material, for enzymatic hydrolysis liberating at least one 6C and/or 5C sugar from an insoluble portion of the lignocellulosic material comprising lignin; and (c) separating at least a portion of the aqueous solution containing the 6C and/or 5C sugar from the insoluble portion. INDEPENDENT CLAIMS are also included for:    (1) a method (II) for isolating components of lignocellulosic material comprising: step (a) as above per se; (b1) enzymatically digesting a first mixture comprising the comminuted lignocellulosic material, a first enzyme blend and a first aqueous solution in the absence of any prior non-enzymatic lignin separation treatment of the lignocellulosic material, for a first enzymatic hydrolysis liberating at least one 6C and/or 5C sugar from a first insoluble portion of the lignocellulosic material comprising lignin; (c1) separating at least a portion of the first aqueous solution containing the 6C and/or 5C sugar from the first insoluble portion; (d) comminuting the first insoluble portion to a comminuted first insoluble portion; (e) enzymatically digesting a second mixture comprising the comminuted first insoluble portion, a second enzyme blend and a second aqueous solution, for a second enzymatic hydrolysis liberating at least one 6C and/or 5C sugar from a second insoluble portion comprising lignin; and (f) separating the second insoluble portion comprising lignin from the second aqueous solution comprising the 6C and/or 5C sugar; and    (2) a system for isolating components of lignocellulosic material comprising: at least one comminutor (A1) for comminuting lignocellulosic material; at least one digester (D1) comprising a vessel equipped with an internal agitator, where the vessel is operable for holding a mixture of the comminuted lignocellulosic material, the enzyme blend and aqueous solution, and operable for enzymatically digesting the mixture with agitation; and a separator (S1) for separating the portion of the aqueous solution from the insoluble portion.