NOVELTY - Cellulose/active substance composite comprises: a regenerated cellulose matrix; and a first active substance comprising a polyamidoamine dendrimer, polyamine dendrimer or polyether amine, where the first active substance is crosslinked with a linker and substantially homogeneously distributed within the matrix of regenerated cellulose.    USE - The cellulose/active substance composite is useful: in membranes/filters, fuel cells, separations devices, electrolysis membranes, flame retardants, biocidal filters, sensors, metal extractants, supports for enzymes, extractant materials for filtration, separations and extractions of metal ions, biomolecules, gas molecules, magnetic particles for membrane/extractant processing, materials modifiers for cellulose coatings, bioactive agents (controlled release, sensing, destruction), metal complexants (sensing, controlled release, extractants and binding and separation agents for filters), water insoluble dyes for coloring cellulose, sensing and indicators, photoresists, incorporation of nanoparticles as photonic agents or UV screens, magnetic particles for magnetoresponsive beads, filtration and reactive beds, nanoparticle catalysis, dispersions of clays and other fire-retardant materials, enzyme supports, supported polymer electrolytes, cavity-forming pillars/scaffolding for the manufacture of nanoporous materials, protective clothing, textiles, bandages, paper, polymeric coatings, slow release therapeutics, wetting agents, foodstuffs, a spray dried emulsion, separation processes (e.g. chromatography), constant flow reactors, and formulation to deliver therapeutic (e.g. cardiovascular therapeutic, anti-cancer therapeutic, CNS therapeutic, hypoglycemic agent, fertility/contraception or woman's health agent, infectious disease therapeutic and pulmonary disease therapeutic) to a subject; and as sensing materials to detect various compounds (e.g. polyphenols, aromatic amines and aminophenols) and solid support materials for enzyme catalyzed transformations. Test details are described but no results given.    ADVANTAGE - The cellulose/active substance composite: utilizes the regenerated cellulose which is, substantially free of an increased amount of substituent groups relative to the starting cellulose and entrapped ionic liquid degradation products; exhibits the loss of first active substance which is less than 5 wt.% of the composite when the composite is placed in excess water; exhibits antibacterial properties or antiviral properties, when it utilizes second active substance as antibacterial or antiviral; achieves a slow delivery effect of the wetting agent over a longer period of time which would be cost effective and time saving for both agriculture and horticulture industries; and provides a formulation, which effectively replaces the emulsifiable concentrates, interfacially-polymerized or wettable powders, and are safer to use.