TECHNOLOGY FOCUS - BIOTECHNOLOGY - Isolation (Disclosed): The phloroglucinol reductase polypeptide is isolated from Eubacterium oxidoreducens. Preferred Polypeptide: The above-mentioned amino acid sequence is at least 60%, 70%, 80%, 90% or 99% homologous to the SEQ ID NO: 4. The polypeptide produced by the above-mentioned cell (C1) and (C2) catalyzes the conversion of phloroglucinol to dihydrophloroglucinol. Preferred Nucleic acid: The above-mentioned nucleic acid sequence is at least 85%, 90%, 95% or 99% homologous to SEQ ID NO: 3. Preferred System: The renewable carbon source is glucose. The system can convert glucose to renewable dihydrophloroglucinol. The system further comprises a proton source for converting the dihydrophloroglucinol to renewable resorcinol. Preferred Cell: The cell (C1) and the cell (C2) transformed with the above-mentioned vector express phospholipase (Phl) D, and are engineered to increase expression of PhlD and do not express at least one chosen from PhlA, PhlB, and PhlC. Preferred Method: The method (M1) further involves contacting the dihydrophloroglucinol and the proton source to produce renewable resorcinol, and performing non-extractive fermentation process. In the method (M3), chemical hydrogenation is not carried out during the step (a). The cells and proteins are removed by at least one process chosen from microfiltration and ultrafiltration. The contacting step involves at least one process chosen from reducing the volume of the culture medium, providing sulfuric acid, refluxing the culture medium and monitoring the production of renewable resorcinol by HPLC. The separation step involves at least one process chosen from extracting the renewable resorcinol into an organic solvent, evaporating the organic solvent to produce oil, and distilling the oil to produce white crystals. ACTIVITY - Muscular-Gen.; Antiseborrheic; Dermatological; Antiinflammatory; Antipsoriatic. No biological data given.    MECHANISM OF ACTION - None given.    EXAMPLE - DNA encoding phloroglucinol reductase was amplified from Eubacterium oxidoreducens G41 genomic DNA using primer having a 35 base pair sequence (SEQ ID NO: 5) fully defined in the specification and primer having a 35 base pair sequence (SEQ ID NO: 6) fully defined in the specification as primer pair. Plasmid pJJ10.043 was constructed by inserting the phloroglucinol reductase gene under T7 promoter into NdeI and XhoI sites of pET22b vector. The obtained plasmid pJJl 0.043 was transformed in Escherichia coli strain BL21 (DE3) and colonies were selected on Luria-Bertani (LB)/ampicillin (Amp) plates. A single colony of the transformed cells was selected and inoculated in shakeflask containing liquid LB/Amp medium and incubated at 37 degrees C for overnight. Fresh LB/Amp liquid medium was inoculated from the overnight culture (1:200 dilution) on the next day and the new shakeflask was incubated at 37 degrees C. When the optical density (OD) value of the culture reached 0.6 at 600, the culture was induced with 0.5 mM of isopropyl beta -D-1-thiogalactopyranoside (IPTG) and heterologous expression of phloroglucinol reductase was performed for 4 hours at room temperature and cell-free lysate of BL21(DE3)/pJJ10.043 exhibiting 100 mu mol/minute/mg specific activity of phloroglucinol reductase was obtained.