NOVELTY - Continuous production of biodiesel using lipase comprises mixing filtered and preheated vegetable fats and oils with lower alcohol thoroughly, passing into a fixed bed reactor and performing immobilized lipase-catalyzed transesterification, where the adding amount of the immobilized lipase is 5-12% of the raw material oil and the fixed bed reactor adopts a tubular structure; fixing the lipase on the filler, reacting at least thrice by adding equal molar amount of lower alcohol every time, separating glycerol by influence of the reaction, separating unreacted lower alcohol and purifying.    USE - The method is useful for producing biodiesel using lipase.    ADVANTAGE - The method: is simple with high production level; is economical; extends the service life of the enzyme; optimizes enzyme catalyzed reaction temperature; and achieves non-pollution zero emission production.    DETAILED DESCRIPTION - Continuous production of biodiesel using lipase comprises: mixing filtered and preheated vegetable fats and oils with lower alcohol thoroughly, passing into a fixed bed reactor and performing immobilized lipase-catalyzed transesterification at 40 plus minus 3 degrees C, where the molar ratio of the raw materials i.e. oil to low alcohol is 1:3-5, the adding amount of immobilized lipase is 5-12% of the raw material oil and the fixed bed reactor adopts a tubular structure; fixing the lipase on the filler, performing the reaction at least thrice by adding equal molar amount of lower alcohol every time, separating glycerol by influence of the reaction, separating unreacted lower alcohol and purifying to obtain biodiesel. An INDEPENDENT CLAIM is also included for a device for continuous production of bio-diesel using lipase comprising a reaction recovery mechanism, a heater and a flash evaporator, where the reaction recovery mechanism comprises at least three groups which are interconnected and each group consists of a mixed tank, a fixed bed reactor, a storage tank, and a liquid-liquid swirler and the last group is connected with the flash evaporator via a heater.    DESCRIPTION OF DRAWING(S) - The diagram shows a schematic representation of the device for continuous production of bio-diesel using lipase.