NOVELTY - Preparing sinomenine hydrochloride infusion solution, comprises either: method one comprising: (a) preparing sinomenine hydrochloride: (A) preparing sinomenine hydrochloride crude product by extracting twice and crystallizing, and (B) refining sinomenine hydrochloride, and (b) preparing sodium chloride infusion solution; or method two comprising: (step a) repeating the same processes as in step (a) of method one, and (step b) preparing glucose infusion solution by e.g. mixing glucose in water for injection, and adding sinomenine hydrochloride, filtering and sterilizing to obtain the product.    USE - The method is useful for preparing sinomenine hydrochloride infusion solution.    ADVANTAGE - The method adopts percolation method to prepare sinomenine hydrochloride, which has simple operation without the requirement of heating process during the extracting process, ensures high yield and simple processing of mother liquid, adopts cold processing, and is safe and causes less pollution.    DETAILED DESCRIPTION - Preparing sinomenine hydrochloride infusion solution, comprises either: method one comprising: (a) preparing sinomenine hydrochloride: (A) preparing sinomenine hydrochloride crude product: (i) extracting: wetting sinomenine crude powder (100-1000 parts) in 0.1-1 mol/l of hydrochloric acid (60-1000 parts by volume) for 0.5-8 hours, transferring into a percolating tank, adding hydrochloric acid (0.1-1 mol/l) to cover the medicine powder at 2-6 cm, soaking for 6-48 hours, percolating at the rate of 2-6 ml/minute for 6-24 hours to obtain the percolate, (ii) extracting: adding lime milk into the percolate to regulate the pH to 10.5-12, then filtering and adding hydrochloric acid into the filtrate to regulate the pH at 7-9.5, extracting with chloroform for 2-5 times, combining the chloroform layers and washing to neutral state, then adding anhydrous sodium sulfate (3-6%) to dehydrate, and vacuum concentrating to recycle chloroform, and (iii) crystallizing: dripping hydrochloric acid (6 mol/l) to regulate the pH to 2-4, and mixing until the floating solids disperse, then cooling, filtering, discarding the filtrate, drying the filter cake at 60-70 degrees C to obtain yellow sinomenine hydrochloride crude product, and (B) refining process of sinomenine hydrochloride: heating and refluxing sinomenine hydrochloride crude product (5-10 parts) in 10-95% ethanol or pure water (30-120 parts by volume respectively) until completely dissolved, then adding activated carbon (4% by wt.) and refluxing for 10-30 minutes, filtering when it is hot, and concentrating the filtrate, cooling, crystallizing and filtering, washing the filter cake with ethanol (95%) until the filtrate is colorless to obtain sinomenine hydrochloride, and (b) preparation of sodium chloride infusion solution: weighing (in parts by wt.) sinomenine hydrochloride (0.3-2), sodium chloride (6-15), and a specific amount of water for injection, mixing and dissolving the sodium chloride in 60-80% of water for injection to obtain a concentrated solution, then adding sinomenine hydrochloride into the concentrated solution, mixing to dissolve, adding activated carbon for injection (0.05-0.5%), mixing and maintaining at 35-45 degrees C for 10 minutes, then filtering out the activated carbon, supplying the water for injection (1000 parts by volume), mixing and examining, filtering with filter element of 0.35-0.55 mu m and 0.1-0.3 mu m respectively if qualified, and then sampling to measure the pH, content, bacterial endotoxin and visible foreign bodies to comply with the national injection standard, and then sterilizing to obtain the product; or method two comprising: (step a) repeating the same processes as in step (a) of method one, and (step b) preparing glucose infusion solution: (i) weighing (parts by wt.) sinomenine hydrochloride (0.32-2), glucose (40-60) and a specific amount of of water for injection, then mixing and dissolving the glucose in 60-80% of water for injection to obtain a concentrated solution, and adding sinomenine hydrochloride into the solution, mixing to dissolve, then adding activated carbon for injection (0.05-5%), mixing and maintaining at 35-45 degrees C for 10 minutes, then filtering out the activated carbon, and (ii) adding the water for injection (1100 parts by volume), then mixing, examining, filtering in filter element of 0.35-0.55 mu m and 0.1-0.3 mu m respectively if qualified, and then sampling to measure the pH, content, bacterial endotoxin and visible foreign bodies to comply with the national standard, and then sterilizing to obtain the product. An INDEPENDENT CLAIM is also included for preparing sinomenine hydrochloride freeze-dried powder injection, comprising: (i) repeating the step (a) of the above mentioned method one; and (ii) mixing and dissolving sinomenine hydrochloride (50-150 parts by wt.) in a specific amount of water for injection, adding activated carbon for injection (0.05-0.5%), incubating at 35-45 degrees C for 5-20 minutes, then filtering out the activated carbon, supplying the water for injection (1000 parts by volume), mixing and examining, filtering with filter element of 0.35-0.55 mu m and 0.1-0.3 mu m respectively if qualified, and then sampling to measure the pH, content, bacterial endotoxin and visible foreign bodies to comply with the national standard, packaging and then freeze drying to obtain the product.