NOVELTY - Preparing caspofungin or its acid addition salt (acetic acid), comprises: reacting N-((2R,6R,11R,14aS,15S,20S,23S,25aR)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-1)(1,4,7,10,13,16)hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide compound (I) with 1,2-diaminoethane.    USE - The process is useful for preparing caspofungin or caspofungin acetate (claimed) which is useful as antifungal agent. No biological data given.    ADVANTAGE - The process solves the problem due to pungent odor and strong toxicity, and provides higher yields of caspofungin in an environmentally friendly and economical manner.    DETAILED DESCRIPTION - Preparing caspofungin or caspofungin acetate, comprises: reacting N-((2R,6R,11R,14aS,15S,20S,23S,25aR)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-1)(1,4,7,10,13,16)hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide compound of formula (I) with 1,2-diaminoethane.    R1 = tetrazole or its derivative (preferred), -(CH2)n-C(=O)OR2, or -(CH2)nC(=O)NH(CH2)m-NH2;    R2 = H or 1-3C alkyl; and    n, m = 1-3.    INDEPENDENT CLAIMS are also included for:    (1) N-((2R,6R,11R,14aS,15S,20S,23S,25aR)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-1)(1,4,7,10,13,16)hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide compound of formula (III), or its acid addition salt or solvate; and    (2) N-((2R,6R,11R,14aS,15S,20S,23S,25aR)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo(2,1-c:2',1'-1)(1,4,7,10,13,16)hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide compound (I), or its acid addition salt or solvate.