TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The method further comprises at least one of: injecting the cooling fluid into the first remaining vaporized compound stream at a second predetermined temperature to form a second aerosol fraction and a second remaining vaporized compound stream, where the second predetermined temperature is less than the vaporization temperature of the second fraction but greater than the vaporization temperature of the second remaining vaporized compound stream; separating the second aerosol fraction from the second remaining vaporized compound stream by electrostatic precipitation at second predetermined temperature; or collecting the second aerosol fraction. The method further comprises: condensing a final vaporized compound stream with a condenser to produce a final liquid fraction and a non-condensable fraction that is further cooled and recirculated as the cooling fluid in step (a); and repeating steps of (a), (b) and (c) at second cooler predetermined temperature to produce and collect second aerosol fraction. Preferred Components: The cooling fluid is gas or liquid which comprises nitrogen, hydrogen, carbon monoxide, carbon dioxide, methane, water, argon, helium and/or an inert gas. The complex mixture of vaporized compounds is a product of pyrolysis of biomass. The first and second predetermined temperatures are less than or equal to 5 degrees C, preferably less than or equal to 1 degrees C. EXAMPLE - Red oak feedstock (0.5 mm) was loaded into feed hopper in bio-oil collection system. The feedstock was entrained in 3 standard liters/minute of nitrogen and silica sand bed was fluidized. The fluidized bed was operated at 500 degrees C and the pyrolysis vapors were then passed through two cyclones which were heat traced at 475 degrees C. The bio-oil collection system was splitting the bio-oil into three fractions using electrostatic precipitator and collecting the aqueous phase. Anhydro sugars and large molecular weight species were collected from first stage fraction (24.9%) at 210 degrees C. Phenolic compounds were collected from second stage fraction (14.6 %) at 85 degrees C and finally third stage fraction (60.5%) at -18 degrees C from bio-oil mass.