NOVELTY - Palladium-nickel/titanium dioxide nano-fiber direct methanol fuel cell anode catalyst comprises titanium dioxide nano-fiber (95-97 mass%) and nano-palladium-nickel (3-5 mass%).    USE - Used as a palladium-nickel/titanium dioxide nano-fiber direct methanol fuel cell anode catalyst.    ADVANTAGE - The method utilizes palladium-nickel which is cheaper than the precious metals e.g. platinum and ruthenium and the dosage of palladium-nickel is relatively low in the catalyst, reduces the cost of the catalyst, and enhances the carbon monoxide toxicity resistance of the catalyst.    DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing the palladium-nickel/titanium dioxide nano-fiber direct methanol fuel cell anode catalyst, comprising: (i) dissolving butyl titanate and polyvinyl pyrrolidone in absolute ethanol, adding the mixture of anhydrous ethanol, glacial acetic acid and de-ionized water into it under stirring condition to form a uniform and transparent sol for electrospinning, where the electrospinning comprises adding sol into the spinning device, adjusting voltage to 30 KV, and maintaining the distance between the spinning head and the tin foil to be 20 cm, spraying sol (2 ml) every hour, and baking the obtained fiber in a muffle furnace at 500 degrees C for 3 hours to prepare titanium dioxide nano-fiber, where the dosage molar ratio of each component ((butyl titanate):(absolute ethanol):(glacial acetic acid):(de-ionized water):(polyvinylpyrrolidone)) for the sol preparation is 1:20-40:1-2.5:2-6:0.1-0.2; (ii) adding titanium dioxide nano-fiber (50-100 mg/ml) into ethylene glycol and dispersing ultrasonically to obtain titanium dioxide nano-fiber dispersive liquid; (iii) dissolving palladium chloride in ethylene glycol to form 5-10 mg palladium/ml of palladium chloride/ethylene glycol solution; (iv) dissolving nickel sulfate in ethylene glycol to form 2-4 mg nickel/ml of nickel sulfate/ethylene glycol solution; (v) synthesizing tungsten-palladium-nickel catalyst (3-5%) with the molar ratio of (palladium):(nickel) is 1:1 to measure palladium chloride/ethylene glycol solution, addition nickel sulfate/ ethylene glycol solution, mixing, performing ultrasonic dispersion and titanium dioxide nano-fiber dispersion liquid to obtain dispersion solution; (vi) dissolving sodium hydroxide in ethylene glycol to prepare sodium hydroxide ethanol solution having concentration of 2 mol/l of sodium hydroxide; (vii) adding sodium hydroxide ethanol solution drop wise into dispersion solution prepared in step (v) and adjusting the pH to 8.5-12 to obtain the suspension; (viii) dissolving potassium borohydride in ethanol solution to prepare potassium borohydride/ethylene glycol solution having concentration of 0.2-0.5 mol/l of potassium borohydride; (ix) adding potassium borohydride/ethylene glycol solution drop wise into the suspension at 80-90 degrees C and stirring under the influence of inert gas and reacting for 2-6 hours; and (x) filtering, washing with de-ionized water to remove chlorine ion or sulfate radical ion from the filtered solution and drying in vacuum condition at 80-120 degrees C to obtain the catalyst.