TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The method comprises reacting at 5-10 degrees C for 40-60 minutes, and then again reacting at room temperature for 1-3 hours. The 2-indenone is prepared into a solution by adding dropwise. The method comprises maintaining the temperature of the reaction solution at 0-5 degrees C during the addition of 2-indenone. The method further comprises purifying N-(2-indane-yl) glycine alkyl ester crude product by washing, extracting an aqueous phase, drying an organic phase, filtering, preparing salt, filtering, neutralizing acid, dissolving the filtering cake, adding water, extracting the aqueous phase, drying the organic phase, filtering, and re-crystallizing. The preparation of salt comprises taking acetone solution of oxalic acid, extracting by using ethyl acetate, methanol, ethanol or acetonitrile as solvent to obtain oxalate, where the extracting solvent is ethyl acetate. The purifying process comprises washing the crude N- (2-indanamine) glycine alkyl ester by using water for two times, extracting the aqueous phase by dichloromethane for two times, drying the organic phase, filtering, rotationally drying the filtering liquid to obtain oil materials, dissolving the oil materials in acetone solution of the oxalic acid, heat preserving at 14 degrees C, reacting to form the salt, filtering, cleaning the filtering cake by acetone for two times, placing the filtering cake in ethyl acetate, dropwise adding triethylamine, neutralizing the N-(2-indane-yl) glycine alkyl ester oxalate, adding water into the solution to dissolve triethylamine oxalate, extracting with ethyl acetate, filtering for two times to obtain an aqueous layer, allowing to stand, combining the organic phase, drying, filtering, rotationally drying the filtrate to obtain the oil materials, completely dissolving the oil materials in ethanol, adding water and seed crystal, separating crystal, filtering, placing the filtrate in an ice water bath, cooling, and drying to obtain N-(2-indane-yl) glycine alkyl ester. The solvent for re-crystallizing is prepared by mixing ethanol with water in a volume ratio of 3:1. Preferred Components: The molar ratio of glycine alkyl ester to 2-indenone to sodium triacetoxyborohydride is (0.60-1.51):1:(0.79-1.59). The oxalic acid utilizes acetone as a solvent.