NOVELTY - (S)-camphor, t-butyl glycinate, solvent and boron trifluoride etherate as catalyst are reacted to obtain ((S)-1,7,7-trimethyl-bicyclo(2.2.1)hept-(2E)-ylideneamino)-acetic acid t-butyl ester. Ether and alkali are added, and reacted with halohydrocarbon to obtain intermediate (I). Alcohol, sodium acetate, hydroxylamine hydrochloride and intermediate are reacted and deprotected to obtain amine compound (II). Compound (II) is resolved, and resolved product (IIa) or (IIb) is hydrolyzed to obtain chiral ( alpha )-hydrocarbyl substituted glycine hydrochloride (IIIa) or (IIIb).    USE - Manufacture of chiral ( alpha )-hydrocarbyl substituted glycine hydrochloride e.g. L-allyl glycine hydrochloride (claimed).    ADVANTAGE - The chiral ( alpha )-hydrocarbyl substituted glycine hydrochloride with purity of more than 99% and high chiral purity is manufactured with high yield by an easy and environmentally-friendly process, under mild reaction conditions.    DETAILED DESCRIPTION - (S)-camphor as chiral auxiliary agent, t-butyl glycinate, solvent and boron trifluoride etherate as catalyst are reacted at 80-110 degrees C. The reaction mixture is washed with alkali and liquid separated. The organic phase is separated to obtain ((S)-1,7,7-trimethyl-bicyclo(2.2.1)hept-(2E)-ylideneamino)-acetic acid t-butyl ester. The mol ratio of the chiral auxiliary agent and t-butyl glycinate is 1.0:1.0-1.8, the mol ratio of the chiral auxiliary agent and boron trifluoride etherate is 1.0:0.01-0.02. Ether solvent and alkali are added to the solution and the mixture is cooled to -20 degrees C to 10 degrees C and liquid separated. The organic phase is concentrated and reacted with halohydrocarbon of formula: X-R, for 1-2 hours at -20 degrees C to 10 degrees C. The reaction mixture is added into water to complete the reaction, and the reaction mixture is liquid separated. The organic phase is concentrated to obtain intermediate of formula (I) having de value of 50-65%. The mol ratio of the main raw material, and halohydrocarbon is 1.0:1.0-1.8, the mol ratio of the main raw material, and alkali is 1.0:1.0-1.8, the dosage ratio of the main raw material, and ether solvent is 1 g:6-12 ml. Alcohol solvent, sodium acetate, hydroxylamine hydrochloride and the intermediate are reacted for 20-50 degrees C, filter-pressed, concentrated and the pH is adjusted to 5-6. The organic phase is concentrated and deprotected to obtain amine compound of formula: R-CH(-NH2)-C(=O)-O-C(-CH3)3 (II). The compound (II) is added to alcohol solvent or ether solvent, and a resolving agent is added and heated to 40-70 degrees C to obtain amine compound of formula (IIa) or (IIb). The resolved product (IIa) or (IIb) is hydrolyzed with an acid to obtain chiral ( alpha )-hydrocarbyl substituted glycine hydrochloride of formula (IIIa) or (IIIb) with ee value of more than 99%.    R=1-12C (un)saturated alkyl or 1-12C (un)saturated phenyl substituted by alkyl;and    X=Cl, Br or I.