NOVELTY - Method of extracting camptothecin (CPT) from Mappia foetida by microorganism solid-state fermentation, involves (a) preparing fermented M.foetida fine powder by taking M.foetida fine powder in container, adding water and flavomycin and fermenting mixture, and (b) taking fermented M.foetida powder, adding 75% ethanol, performing extraction, filtering the extract, collecting the filtrate, performing the above-mentioned process in step (b) for three times, combining extracts, crystallizing the product, and drying washed crystals.    USE - The method is useful for extracting CPT from M.foetida by microorganism solid-state fermentation (claimed).    DETAILED DESCRIPTION - Method of extracting camptothecin (CPT) from Mappia foetida by microorganism solid-state fermentation, involves (a) taking 100 pts. mass M.foetida fine powder in container, adding water and 1-2 pts. mass flavomycin, uniformly stirring the mixture, covering the stirred mixture in container using lid, controlling the temperature at 23-30 degrees C, fermenting the mixture for 72-120 hours and drying the CPT ethanol extract, and (b) taking 100 pts. mass fermented M.foetida powder, adding 750-850 pts. mass 75% ethanol, performing extraction for 3.5-4.5 hours, filtering the extract, collecting the filtrate, adding 450-550 pts. mass 75% ethanol to the concentrated residue, performing extraction for 2.5-3.5 hours, filtering the extract, collecting the filtrate, again adding 250-350 pts. mass 75% ethanol to the concentrated residue, performing extraction for 1.5-2.5 hours, filtering the extract, collecting filtrate, combining the ethanol extracts for three times, evaporating the residue until the residue has no alcohol taste, adding 480-520 pts. mass water to the residue, adjusting pH of the mixture to 9-10, performing adsorption on macroporous resin column, eluting the mixture using ethanol, recovering ethanol, performing liquid extraction using ethyl acetate, recycling acetate, crystallizing the product using methanol, recrystallizing the crystal using methyl chloride, washing the crystals using distilled water, drying the washed crystals under reduced pressure, and collecting CPT having purity of 98.7%.