NOVELTY - Accelerating nutrient uptake in bacteria or yeast without a substantially commensurate increase of biomass or increase in biofilm production comprises contacting the bacteria or yeast with a mixture of an aerobic yeast fermentation supernatant and a surface-active agent.    USE - The method is used for accelerating nutrient uptake in bacteria or yeast without a substantially commensurate increase of biomass or increase in biofilm production (claimed). The compositions prepared by the preceding processes are useful in a number of applications where bacteria, or yeast, are utilized in the application. For example, the compositions may be useful in applications having as a goal the destruction or removal of organic compounds, such as treating wastewater or other bioremediation. Alternatively, the compositions may be useful in applications having as a goal the creation of fermentation beer or antibiotics. Other types of applications for which the compositions may be useful are those in which biomass or biofilm production is sought to be minimized, which is achieved by the compositions by the uncoupling of the ATP cycle and the effect on reproduction of bacteria and production of polysaccharides (biofilm). These applications are useful, for example, in the reduction of hydrogen sulfide in sewers where bacteria form biofilm, thus creating anaerobic conditions that are conducive to the production of hydrogen sulfide, or in the reduction of calcium carbonate in cooling towers where calcium salts peg onto biofilm and clog circulation systems, or in the minimization or elimination of biofilm in medical products. Specific applications include, but are not limited to, the following: municipal wastewater plants, industrial wastewater plants (particularly food processing), sewage lines, septic tanks and septic fields, cross-flow membrane filtration systems, cooling towers, soil remediation, bilgewater in ships, odor control applications, agricultural applications (e.g., cattle and chicken manure ponds), clarification of standing bodies of water in facultative lakes, ponds, and lagoons, pools/spas, cleaners for non-sterile environments, and the like.    DETAILED DESCRIPTION - Accelerating nutrient uptake in bacteria or yeast without a substantially commensurate increase of biomass or increase in biofilm production comprises contacting the bacteria or yeast with a mixture of an aerobic yeast fermentation supernatant and a surface-active agent, where the nutrient uptake in the bacteria is increased without a substantially commensurate increase of biomass or increase in biofilm production, where the mixture of the aerobic yeast fermentation supernatant and the surface-active agent is obtained by: fermenting under aerobic conditions yeast cells in the presence of a nutrient source, heating the yeast cells after the fermenting step to obtain a fermentation product, centrifuging the fermentation product to obtain the aerobic fermentation supernatant containing peptides, and combining the aerobic fermentation supernatant with the surface-active agent.