NOVELTY - Extraction of solanesol comprises pre-treating tobacco solid waste as raw material, adding water, putting in oven, baking for 90 minutes in the oven of 85-110 degrees C, crushing, screening for 20-160 meshes sieve, collecting sieved raw material, and processing enzymolysis with tobacco solid waste and enzyme and water; and collecting filtrate into extracting container, mixing tobacco solid waste and organic extracting agent, collecting lower layer of organic phase, decompressing and concentrating filtrate.    USE - Method of extraction of solanesol (claimed).    ADVANTAGE - The method has low energy consumption, less organic solvent use amount, and good for environmental protection.    DETAILED DESCRIPTION - Extraction of solanesol comprises:    (A) pre-treating tobacco solid waste as raw material, adding water, putting in oven, baking for 90 minutes in the oven of 85-110 degrees C, crushing, screening for 20-160 meshes sieve, collecting sieved raw material, and processing enzymolysis with tobacco solid waste and enzyme and water mass ratio of 1 g:0.1-0.6 g:1-15 ml, adding enzyme and water, stirring uniformly, using sulfuric acid or sodium hydroxide solution to adjust pH to 4-9, placing in the cradle, with temperature of water bath at 25-60 degrees C, activating for 2-14 hours, filtering filter pump, and respectively collecting filtrate and filter residue, with the enzyme comprising cellulase, ligninase or cellulase and ligninolytic enzymes compound at mass ratio of 1:1-6;    (B) collecting filter residue, putting into extracting container, pre-processing tobacco solid waste of quality composite extracting agent solution of volume ratio of 1 g:8-12 ml, adding composite extracting agent solution, stirring and mixing uniformly, under ultrasonic power of 40-200 W, at 30-55 degrees C, ultrasonic processing for 5-40 minutes, using filter for filtering, respectively collecting filtrate and filter residue, collecting filtrate to centrifuge, with centrifuge speed of 3000-4000 revolutions/minute, centrifugally separating for 5-15 minutes, respectively collecting centrifugal clear solution and centrifuging slag, with composite extracting agent solution containing ethanol and methanol mass concentration ratio of 1:4-9;    (C) collecting centrifugal clear solution by high performance liquid chromatography to measure concentration of solanesol, collecting centrifugal clear liquid, placing in rotating evaporimeter under 0.1-5-6 MPa, at 30-60 degrees C, decompressing and concentrating filtrate to paste to obtain solanesol crude product, adding solanesol crude product and composite extracting agent solution, mixing and dissolving uniformly, rotating evaporator under 0.1-5.6 MPa at 30-60 degrees C, decompressing and concentrating for second time, and repeating 1-3 times to obtain solanesol product; and    (D) collecting filtrate into extracting container, mixing tobacco solid waste and organic extracting agent with ratio of 1 g:5-10 ml, adding organic extracting agent, stirring and mixing uniformly, extracting and standing for 10-30 minutes, respectively collecting upper layer water phase and lower layer of organic extraction phase, collecting lower layer of organic phase, placing in rotating evaporimeter under 0.1-5.6 MPa at 30-60 degrees C, decompressing and concentrating filtrate to paste, taking nicotine to obtain crude product, with organic extraction agent comprising diethyl ether or acid ester.