TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Method: The method further comprises quantifying the synthesis of gold nanoparticles by inductively coupled plasma spectroscopy. The gold ion solution is prepared by dissolving at least one gold salt consisting of gold (III) chloride and gold (I) chloride in deionized water. The method step of exposing further comprises mixing the fungal biomass, and the solution containing gold ions. The step of exposing comprises monitoring the synthesis of gold nanoparticles by at least one technique consisting of visual inspection, UV-visible spectroscopy, atomic force microscopy and inductively coupled plasma spectroscopy, dynamic light scattering and transmission electron microscopy. Preferred Components: The shape of the gold nanoparticles is triangular, spherical or hexagonal. The size of the stable gold nanoparticles is 5-60 nm.    TECHNOLOGY FOCUS - INSTRUMENTATION AND TESTING - Preferred Components: The device for quantifying the synthesis of gold nanoparticles, comprises an inductively coupled plasma spectrometer.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The preparation of culture comprises: isolating Tritirachium fungus; purifying and subculturing Tritirachium fungus; cultivating Tritirachium fungal biomass in potato dextrose medium; separating the fungal biomass from the medium by filtration; and washing the biomass with sterile distilled water, where the fungal biomass comprises Tritirachium album. Preferred Composition: The formulation further contains at least one pharmaceutical excipient consisting of preservatives, cryoprotectants, tonicity adjusting agents, solubilizing agents, pH adjusting agents, buffering agents, taste masking agents, sweeteners, flavors, diluents, disintegrants, lubricants, glidents, binders, solvents, matrix forming agents, coating polymers, effervescent agents, wetting agents and dispersing agents. The formulation is in the form of soaps, pills, powder, granules, tablet, capsule, lozenges, solution, liquid suspension, sprays, foam or aerosols. EXAMPLE - Biomass of the fungus Tritirachium album was cultivated in potato dextrose medium, and was separated from the medium by filtration. Then the fungal biomass was washed thoroughly with sterile distilled water and 5 g of fresh weight of Tritirachium album was taken for the bioproduction of gold nanoparticles. A gold ion solution was prepared by dissolving gold (III) chloride in deionized water to obtain a final solution with concentration of 0.1-10 mM. 5 g of Fungal biomass was exposed to each gold ion solution and incubated at 20-45 degrees C under static condition. The biomass was separated from the flask by filtration, dried and manually macerated. The biomass was then subjected to sonication and filtration to obtain the gold nanoparticle extract.