NOVELTY - Preparing (3 beta )-17-(3-pyridyl)-androsta-5,16-dien-3-ol acetate (I), comprises e.g. reacting dehydroepiandrosterone (IV) with a silane reagent under action of a catalyst to obtain dehydroepiandrosterone compounds (V), reacting (V) with a Grignard reagent under action of a catalyst to obtain 17-hydroxy-17-(3-pyridyl)-androsta-3 beta -ol-5-ene compounds (VI), reacting (VI) with a dehydrating agent under action of a catalyst to obtain 17-(3-pyridyl)-androsta-5,16-dien-3 beta -ol compounds (VII), then deprotecting (VII) to obtain 17-(3-pyridyl)-androsta-5,16-dien-3 beta -ol (VIII), and acetylating (VIII).    USE - The method is useful for preparing (3 beta )-17-(3-pyridyl)-androsta-5,16-dien-3-ol acetate (claimed).    ADVANTAGE - The method: utilizes cheap and easily available raw materials; is economical and environment-friendly; has simple continuous operation, simple post-treatment, and high product quality and yield; and is suitable for industrial production.    DETAILED DESCRIPTION - Preparing (3 beta )-17-(3-pyridyl)-androsta-5,16-dien-3-ol acetate (I), comprises (i) carrying out substitution reaction of dehydroepiandrosterone (IV) with a silane reagent under action of a catalyst to obtain dehydroepiandrosterone compounds of formula (V), where the catalyst is 4-dimethylaminopyridine, triethylamine, tributylamine, pyridine or 2,6-dimethylpyridine, and the silane reagent is trimethylchlorosilane, tert-butyldimethylchlorosilane or triethylchlorosilane, (ii) reacting (V) with a Grignard reagent under action of a catalyst to obtain 17-hydroxy-17-(3-pyridyl)-androsta-3 beta -ol-5-ene compounds of formula (VI), where the Grignard reagent is 3-pyridylmagnesium bromide, and the catalyst is ferric chloride, cerium chloride, aluminum chloride, titanium trichloride, zinc chloride, lanthanum chloride, neodymium chloride or praseodymium chloride, (iii) carrying out dehydration reaction of (VI) with a dehydrating agent under action of a catalyst to obtain 17-(3-pyridyl)-androsta-5,16-dien-3 beta -ol compounds of formula (VII), where the dehydrating agent is methanesulfonyl chloride, p-toluenesulfonyl chloride, acetic anhydride, trifluoroacetic anhydride, methanesulfonic anhydride, trifluoromethanesulfonic anhydride or p-toluenesulfonic acid anhydride, and the catalyst is triethylamine, pyridine or 4-dimethylaminopyridine, then (iv) carrying out deprotection of (VII) by using a deprotecting reagent to obtain 17-(3-pyridyl)-androsta-5,16-dien-3 beta -ol (VIII), where the deprotecting reagent is tetrabutylammonium fluoride, tetrabutylammonium chloride, tetrabutylammonium bromide or hydrochloric acid, and (v) carrying out acetylation of (VIII) with an acetylation reagent under action of a catalyst, where the acetylation reagent is acetyl chloride or acetic anhydride, and the catalyst is 4-dimethylaminopyridine, triethylamine or pyridine.    R = trimethylsilyl, tert-butyldimethylsilyl or triethylsilyl.