TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Composition: The adhesive layer further contains plate-shaped inorganic compound (C) having non-swelling property with respect to water. The content of inorganic compound is 5-50 parts mass with respect to 100 parts mass total content of polyester polyol (A), polyisocyanate (B) and inorganic compound (C). The inorganic compound contains particles having size of 0.1 mu m or more.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Composition: The adhesive layer is obtained by dissolving polyester polyol (A) in ketone solvent and/or ester solvent. Preferred Layer: The multilayer film has base film layer or sealant layer other than the layer containing aluminum vapor deposition layer or aluminum foil.    TECHNOLOGY FOCUS - POLYMERS - Preferred Composition: The polyester polyol (A) has an aromatic ring, and is chosen from polyester polyols (A1-A5). The polyester polyol (A1) has 1 or more carboxy groups and 2 or more hydroxyl groups, and is obtained by reacting carboxylic anhydride or polycarboxylic acid with polyester polyol having 3 or more hydroxyl group. The polyol (A1) has hydroxyl value of 20-250 and acid value of 20-200. The polyester polyol (A2) has polymerizable carbon-carbon double bond in molecule. The monomer component having polymerizable carbon-carbon double bond in polyester polyol (A2) is maleic acid, maleic anhydride or fumaric acid. The content of monomer component having carbon-carbon double bond is 5-60 parts mass with respect to 100 parts mass total monomer component. The polyester polyol (A3) contains 5 %mass or more glycerol residue of formula (I). The polyester polyol (A4) is obtained by polycondensing polyvalent carboxylic acid component containing ortho orientation aromatic dicarboxylic acid or its anhydride, and polyhydric alcohol component containing ethylene glycol, propylene glycol, butylene glycol, neopentyl glycol and/or cyclohexane dimethanol. The ortho orientation aromatic dicarboxylic acid or its anhydride contains 70-100 %mass polyhydric carboxylic acid chosen from ortho phthalic acid, naphthalene-2,3-dicarboxylic acid, naphthalene-1,2-dicarboxylic acid, anthraquinone-2,3-dicarboxylic acid and 2,3-anthracene dicarboxylic acid or their anhydride. The polyester polyol (A5) has isocyanuric ring of formula (II).R1-R3=H or group (G) of formula: -(C(=O)-X-C(=O)-O-Y'-O)n-H;n=1-5;X=optionally substituted 1,2-phenylene, 1,2-naphthylene, 2,3-naphthylene, 2,3-anthraquinone diyl, arylene or 2,3-anthracenediyl, and at least one is group (G);Y'=2-6C alkylene group;R4-R6=-(CH2)n1-OH or -(CH2)n2-O-(C(=O)-X-C(=O)-O-Y'-O)n3-H;n1,n2=2-4;andn3=1-5.Polyisocyanate (B) contains polyisocyanate having aromatic ring, which is metaxylene diisocyanate or reaction product of metaxylene diisocyanate and alcohol having 2 or more hydroxyl groups. The adhesive layer further contains crystalline polyester.