NOVELTY - Making acetone-butanol involves injecting acetone-butanol-ethanol (ABE) culture into preheated biomass; putting fermentation liquor in fermentation tank into pervaporation permselective membrane separator; collecting penetrating fluid; inputting ABE into extraction column; and discharging aqueous phase into storage tank and organic phase into ding tower; removing water in organic phase; concentrating aqueous phase in aqueous phase storage tank through pervaporation permselective membrane component; and again entering concentrated solution into extraction column; and circulating.    USE - For making acetone-butanol (claimed).    ADVANTAGE - The method provides high yield of acetone-butanol; saves energy consumption in separating process; and improves the competitive power of using biomass fermentation method to produce butanol.    DETAILED DESCRIPTION - Making acetone-butanol using biomass fermentation-pervaporation membrane coupling technique, involves (a) using the preheated biomass as fermentation substrate; injecting the ABE culture to ferment; (b) putting the fermentation liquor in the fermentation tank into the pervaporation permselective membrane separator through a pump; collecting the penetrating fluid to get the concentrated solution of acetone, butanol and ethanol, flowing back the trapped fluid into the fermentation tank; (c) inputting the concentrated solution of acetone, butanol and ethanol in step (b) into the extraction column through a pump, where the concentrated solution is divided into organic phase and aqueous phase in extraction column; and (d) discharging the aqueous phase obtained in step (c) into the aqueous phase storage tank through a pump and the organic phase directly entering into the ding tower and the follow-up rectifying tower groups without passing through the beer still; realizing removing a little water in the organic phase to obtain the anhydrous acetone, butanol and ethanol; concentrating the aqueous phase in the aqueous phase storage tank through pervaporation permselective membrane component; and again entering the concentrated solution into the extraction column to carry out phase separation; and circulating.