TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The conversion of R1 group into a carboxyl group comprises a heterogeneous phase that is catalyzed by palladium catalyst. The heterogeneous phase comprises an aqueous base and chloroform, preferably aqueous potassium hydroxide. The palladium catalyst is bis(triphenylphosphine)palladium (II) dichloride. SPECIFIC COMPOUNDS - 08 Tri-tertiary-butylcarboxy-phthalocyanine compounds are specifically claimed, e.g. (9,16,23-tri-tertiary-butyl-2-carboxy-5,28:14,19-diimino-7-tetrabenzo,12:21,26-dinitrile(c,h,m,r)(1, 6,11,16)tetraazacycloeicosanoate-(2-)N29,N30,N31,N32)-zinc (II), (9,16,24-tri-tertiary-butyl-2-carboxy-5,28:14,19-diimino-7-tetrabenzo,12:21,26-dinitrile(c,h,m,r)1,6,11,16)tetraazacycloeicosanoate-(2-)N29,N30,N31,N32)-zinc (II), (9,17,23-tri-tertiary-butyl-2-carboxy-5,28:14,19-diimino-7-tetrabenzo,12:21,26-dinitrile(c,h,m,r)(1, 6,11,16)tetraazacycloeicosanoate-(2-)N29,N30,N31,N32)-zinc (II), (9,17,24-tri-tert-butyl-2-carboxy-5,28:14,19-diimino-7-tetrabenzo,12:21,26-dinitrile (c,h,m,r)(1,6,11,16) tetraazacycloeicosanoate-(2-)N29,N30,N31,N32)-zinc (II) or (10,16,23-tri-tertiary-butyl-2-carboxy-5,28:14,19-diimino-7-tetrabenzo,12:21,26-dinitrile(c,h,m,r)(1,6,11,16) tetraazacycloeicosanoate-(2-)N29,N30,N31,N32)-zinc (II).    EXAMPLE - The example illustrates the preparation of (9(10),16(17),23(24)-tri-tertiary-butyl-2-carboxy-5,28:14,19-diimino-7,12:21,26-dinitrile tetrabenzo(c,h,m,r)(1,6,11,16)-tetraazacycloeicosanoate-(2-)-N29,N30,N31,N32)-zinc (II) (a mixture of regioisomers). A mixture of iodine-tri-tert.-butylphthalocyanine (81 mg, 0.09 mmol) in 30 ml of chloroform and 18 ml of potassium hydroxide (40% in water) was degassed by two cycles of freezing and thawing in vacuum. A catalyst bis(triphenylphosphine)palladium (II) dichloride (7 mg, 0.009 mmol) was added under an argon atmosphere, where the biphasic mixture was allowed to react at room temperature for 18 hours during stirring at moderate speed. The organic phase was separated and washed with water and aqueous hydrochloric acid (5% in water). The formed organic layer was dried with anhydrous magnesium sulfate, where the solvent was evaporated under reduced pressure to form a residue. The formed residue was purified by column chromatography by using tetrahydrofuran/hexane as eluent and then purified by filter column chromatography by using reversed-phase silica gel and methanol/tetrahydrofuran (9:1) to form a mixture of regioisomers with 69% yield.