NOVELTY - A high-silicon zeolite carrier is calcined, subjected to ammonium-ion-exchange treatment, washed, dried, and calcined to obtain hydrogenous zeolite. Hydrogenous zeolite is hole-processed, washed, dried, calcined, purified by vacuum-degassing pretreatment, loaded with gold, solid-liquid separated, washed, dried, and calcined. Conversion of n-butane to isobutane is carried out by isomerization in a fixed bed reactor using extrusion-molded catalyst, moving bed reactor using catalyst pellets, or fluidized bed reactor using spray-granulated catalyst.    USE - Conversion of n-butane into isobutane using gold-supported zeolite catalyst (claimed).    ADVANTAGE - The method uses deposition-precipitation under negative pressure, which is in favor of cleaning the internal and external surfaces and the channels of zeolite, such that gold easily enters the channels of zeolite to reach high dispersion. The supported gold catalyst has an acid site and a metal active site required for isomerization of n-butane, such that n-butane is dehydrogenated under metal and acid difunctional action to generate olefin, olefin obtains a proton from the acid site to form a carbonium ion, and the carbonium ion undergoes skeletal isomerization and hydrogenation desorption to generate isobutane.    DETAILED DESCRIPTION - A high-silicon zeolite carrier having a silicon/aluminum ratio of greater than 10 and a grain size of 5 nm to 30 mu m, is calcined at 400-600 degrees C for 3-8 hours. The calcined zeolite is subjected to ion-exchange treatment at 20-80 degrees C using 0.05-1 mol/L ammonium nitrate, ammonium chloride, or ammonium carbonate solution. The volume ratio of ammonium salt solution and zeolite is 3:1-10:1, processing time is 0.2-100 hours, and sodium ion content after 1-5 times of exchange is less than 1%. The zeolite carrier is washed with deionized water, dried at 80-200 degrees C for 1-100 hours, and calcined at 400-600 degrees C for 3-8 hours to obtain hydrogenous zeolite. Hydrogenous zeolite is hole-processed at 20-80 degrees C for 1-5 hours using 0.05-6 mol/L hydrochloric acid, nitric acid, sulfuric acid, or citric acid solution, washed with deionized water to neutral, dried at 50-200 degrees C for 3-20 hours, and calcined at 300-600/ for 1-4 hours. The volume of acid solution and zeolite is 3:1-10:1. The zeolite carrier is then purified by vacuum-degassing pretreatment at 20-90 degrees C and -0.01 MPa to -0.1 MPa for 0.5-12 hours, under stirring conditions. The zeolite carrier is contacted with a gold precursor solution, a precipitating agent is added to the mixture, and precipitation reaction of gold is carried out by vacuum deposition for 5-100 hours. After solid-liquid separation, the solid is washed with deionized water until no chloride ions are present, dried at 80-200 degrees C for 0.5-100 hours, and calcined at 300-700 degrees C for 3-20 hours in a muffle furnace or plasma-roasted in nitrogen, helium, argon, air or oxygen atmosphere. Conversion of n-butane to isobutane is carried out by isomerization in a fixed bed reactor using extrusion-molded catalyst at 150-600 degrees C, 0.3-3 MPa, and 0.5-20 hour-1, moving bed reactor using catalyst pellets at 150-600 degrees C, 0.1-0.5 MPa, and 0.5-20 hour-1, or fluidized bed reactor using spray-granulated catalyst having a particle size of 20-120 microns at 150-600 degrees C, 0.1-0.3 MPa, and agent/hydrocarbon ratio of 0.5-5.