NOVELTY - Vinpocetine is synthesized by adding vincamine and toluene, stirring in ice water bath, dropping triethylamine, slowly dripping methanesulfonyl chloride, and continuously stirring to react for 5 hours at room temperature; evaporating solvent, adding ethanol and water, separating solid, then filtering, and vacuum drying to obtain vinpocetine intermediate; adding anhydrous ethanol with sodium ethoxide, then adding vinpocetine intermediate, placing in oil bath of 80 degrees C to react for 12 hours; and evaporating solvent, extracting with ethyl acetate, and separating out solid to obtain vinpocetine.    USE - Method of synthesizing vinpocetine (claimed).    ADVANTAGE - The method has short reaction step, high product purity and high yield, low energy consumption, and little pollution to the environment.    DETAILED DESCRIPTION - Synthesis of vinpocetine comprises:    (A) adding vincamine (500 g) into 5-L three-mouth bottle, then adding toluene (2 L), stirring in ice water bath, dropping triethylamine (244.4 g), after 10 minutes, slowly dripping methanesulfonyl chloride (176.8 g), stirring in ice water bath for 2 hours, then slowly raising temperature to room temperature, and continuously stirring for 5 hours;    (B) stopping the reaction, evaporating solvent, adding ethanol and water (2000 ml:200 ml), adjusting pH to 12 with saturated potassium carbonate solution, where at this time, a large number of solid is separated out, then filtering, and vacuum drying to obtain vinpocetine intermediate;    (C) adding anhydrous ethanol (3 L) in a 5-L three-mouth bottle, stirring in ice water bath for 1 hour, slowly adding sodium ethoxide (180 g), stirring for 5 hours, then adding vinpocetine intermediate (578. 6 g), and then placing the reaction bottle in oil bath of 80 degrees C, and reacting for 12 hours; and    (D) evaporating most of the solvent, then pouring the solution into 4 mol/L hydrochloric acid solution (800 ml), extracting with ethyl acetate (500 ml), adjusting pH value of aqueous phase to 12, separating out the solid, filtering and drying to obtain the vinpocetine.