NOVELTY - Preparing rivaroxaban (I), comprises reacting 4-(4-aminophenyl)morpholine-3-one (II) with 2-((2S)-oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione (III) to obtain 2-((2R)-2-hydroxy-3-((4-(3-oxomorpholin-4-yl)phenyl)amino)propyl)-1H-isoindole-1,3(2H)-dione (IV), preparing 2-((2R)-2-hydroxy-3-((4-(3-oxomorpholin-4-yl)phenyl)amino)propyl)isoindoline-1,3-dione (V), eliminating the pthalamide group from (V) to obtain 4-(4-((5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl)phenyl)morpholin-3-one (VI) and reacting (VI) with 5-chlorothiophene-2-carbonyl chloride (VIII) to obtain (I).    USE - The method is useful for preparing rivaroxaban, which is useful for the prevention and treatment of thromboembolic diseases including pulmonary embolism, deep venous thrombosis, myocardial infarction, angina pectoris, reocclusion and restenosis after angioplasty or aortocoronary bypass, cerebral stroke, transitory ischemic attacks and peripheral arterial occlusive diseases. No biological data given.    ADVANTAGE - The user friendly method ensures simple, economical and efficient preparation of rivaroxaban without potential impurities in an eco-friendly manner and eliminates laborious workup and extensive purifications.    DETAILED DESCRIPTION - Preparation of rivaroxaban (I), comprises: either reacting 4-(4-aminophenyl)morpholine-3-one (II) with 2-((2S)-oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione (III) in a first solvent to obtain 2-((2R)-2-hydroxy-3-((4-(3-oxomorpholin-4-yl)phenyl)amino)propyl)-1H-isoindole-1,3(2H)-dione (IV), preparing 2-((2R)-2-hydroxy-3-((4-(3-oxomorpholin-4-yl)phenyl)amino)propyl)isoindoline-1,3-dione (V) by reacting (IV) using a phosgene or phosgene equivalent(s) or anhydrides or bis(aryl) carbonate of formula (Ar1-O-C(=O)-O-Ar1) (XVI), in a second solvent and optionally in presence of a base, eliminating the pthalamide group from (V) in the first solvent using a de-protecting agent to obtain 4-(4-((5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl)phenyl)morpholin-3-one, (VI) optionally isolating and purifying (VI) and optionally converting to its acid addition salt, reacting (VI) or acid addition salt with 5-chlorothiophene-2-carbonyl chloride (VIII) in a third solvent and in presence of a base to obtain (I) and isolating (I) or optionally, the reaction is carried out in biphasic medium and in the presence of a phase transfer catalyst and optionally, purifying (I); or reacting (VI) with a (5-chlorothiophene-2-carbonyl)compound of formula (IX) in a solvent and in presence of a base to provide (I) and optionally purifying (I); or reacting (VI) with 5-chlorothiophene-2-carbaldehyde (XII) in a solvent, optionally in presence of a base, optionally in presence of a catalyst to obtain 4-(4-((5R)-5-(((5-chloro-2-thienyl)methyleneamino)methyl)-2-oxo-oxazolidin-3-yl)phenyl)morpholin-3-one (XV) and optionally isolating (XV), oxidizing (XV) using an oxidizing agent(s), in a solvent, optionally in the presence of a base and a catalyst to obtain (I) and optionally purifying (I); or oxidizing (5-chloro-2-thienyl)methanol (XVII) using an oxidizing agent to obtain (XII) in a solvent and optionally in presence of a catalyst, reacting (XII) with (VI) or its acid addition salt in a solvent, optionally in the presence of a base and a catalyst to obtain (XV) and optionally isolating (XV) and oxidizing (XV) using an oxidizing agent(s), in a solvent and optionally in the presence of a base and a catalyst to obtain (I) and optionally purifying (I).    Ar1 = optionally substituted phenyl including p-nitrophenyl, 4-(trifluoromethyl)phenyl or 4-cyanophenyl;    X = sulfonyloxy, imidazole, triazole, tetrazole, alkoxy, substituted alkoxy, tri-halomethoxy, N-hydroxysuccinamide, p-nitrophenol, N-hydroxythalamide, N-hydroxybenzotriazole, or OR; and    R = alkyl or optionally substituted aryl.    INDEPENDENT CLAIMS are included for:    (1) (4-nitrophenyl) 5-chlorothiophene-2-carboxylate (XIII);    (2) 4-(4-((5R)-5-(((5-chloro-2-thienyl)methyleneamino)methyl)-2-oxo-oxazolidin-3-yl)phenyl)morpholin-3-one (XV); and    (3) (5-chlorothiophene-2-carbonyl)compound (IX).