TECHNOLOGY FOCUS - BIOLOGY - Preferred Components: The oil-containing microbe comprises yeast, algae, fungi, bacteria, euglenoids, stramenopiles, oomycetes, or at least one polyunsaturated fatty acid in the oil. The moisture level of the microbial biomass is 1-10 wt.%. The microbial biomass is a disrupted biomass, having a disruption efficiency of at least 50% of the oil-containing microbes. The microbial biomass is disrupted to produce a disrupted biomass in a twin screw extruder having a total specific energy input (SEI) of 0.04-0.4 kW/(kg/hour), compaction zone using bushing elements with progressively shorter pitch length, and a compression zone using flow restriction.    TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The grinding agent has a property comprising at least one grinding agent particle having a Moh hardness of 2-6 and an oil absorption coefficient of greater than or equal to 0.8 as determined according to ASTM method D1483-60. The grinding agent comprises silica or silicate. The grinding agent is present in an amount of 1-20 wt.% based on the summation of the weight of microbial biomass, grinding agent and binding agent in the solid pellet.    TECHNOLOGY FOCUS - INSTRUMENTATION AND TESTING - Preferred Components: The solid pellets are formed using a granulator, are dried using a fluid bed dryer, or are formed using a granulator and are dried using a fluid bed dryer. The compaction zone is prior to the compression zone within the extruder. The flow restriction is provided by reverse screw elements, restriction/blister ring elements or kneading elements.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Process: The process further comprises extracting the solid pellet with a solvent to provide an extract comprising the oil. The steps (a) and (b) are performed in an extruder. The steps (a) and (b) are performed simultaneously in an extruder. The step (c) comprises (c1) extruding the fixable mix through a die to form strands, (c2) drying and breaking the strands, and (c3) combining step (c1) and (c2). Preferred Components: The solid pellets have an average diameter of 0.5-1.5 mm, an average length of 2-8 mm, and a moisture level of 0.1-5 wt.%. The binding agent comprises water and carbohydrates including sucrose, lactose, fructose, glucose or soluble starch. The binding agent is present in an amount of 0.5-10 wt.%, based on the summation of the weight of microbial biomass, grinding agent and binding agent in the solid pellet. The solvent comprises liquid or supercritical fluid carbon dioxide. EXAMPLE - No suitable example given.