TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The base is alkali or alkaline metal hydroxides or carbonates. The reducing agent is Raney-nickel, palladium on carbon, platinum on carbon or rhodium on carbon.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The organic solvent includes hydrocarbons, halogenated solvents, nitriles, amides, alcohols, ketones, and/or esters, preferably toluene, xylene, ethyl benzene-dimethylformamide, dimethyl acetamide, methylene dichloride, acetonitrile, 1-4C-straight chain or branched alcohols, acetone, methyl isobutyl ketone, methyl ethyl ketone, ethyl acetate, isopropyl acetate and butyl acetate. (II) in solid state form has water content of 4-5.5%. ACTIVITY - Endocrine-Gen.; Antithyroid.    MECHANISM OF ACTION - None given.    EXAMPLE - 90 ml of Water, 30 g of R-(+)-1-(1-naphthyl)ethylamine tartrate and 90 ml of toluene were added in a round bottom flask at 25-35 degrees C. The pH of reaction mass was adjusted to 12.5-13.5 by adding 10% of sodium hydroxide solution and stirred for 30 minutes. Toluene layer was separated and toluene was distilled out under vacuum at a temperature of below 70 degrees C to obtain R-(+)-1-(1-naphthyl) ethylamine. The residue was cooled to 25-35 degrees C, and 200 ml of methanol was added to the residue. The reaction mass was transferred into a 2 l autoclave. The reaction mass was stirred for 30 minutes. 2 g of Raney-nickel was added under nitrogen. The reaction mass was hydrogenated at 50-55 degrees C and maintained for 6-8 hours. Pressure was released and reaction mass was filtered and washed with 20 ml of methanol. The pH of reaction mass was adjusted to 1-2 with 10-15 ml of concentrated hydrochloric acid, and the methanol was distilled out under vacuum at temperature of below 50?OC. The residue was cooled to 25-35 degrees C, 60 ml of methanol was added and reaction mass was heated to 35-45 degrees C and further cooled to 25-35 degrees C. The reaction mass was filtered and washed with 50% aqueous methanol. The reaction mass was treated with 100 ml of water and maintained for 45 minutes. The reaction mass was filtered and washed with water to obtain cinacalcet hydrochloride.