TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The step (a) comprises: isomerizing the hydrocarbon feed and the recycle stream (preferred); or isomerizing the hydrocarbon feed and the hexane-depleted raffinate stream. The hexane-containing raffinate stream further comprises linear pentane, where the step (b) comprises: adsorbing linear pentane and linear hexane from the isomerized hydrocarbon stream to form the hexane-containing raffinate stream separated from the isomerate product stream; and fractionating the isomerized hydrocarbon stream to produce the isomerate product stream and the hexane-containing raffinate stream. The step (c) comprises: fractionating at least a portion of the hexane-containing raffinate stream to produce the linear hexane stream and the hexane-depleted raffinate stream; or adsorbing linear hexane from at least a portion of the hexane-containing raffinate stream to produce the linear hexane stream and the hexane-depleted raffinate stream. In the methods (M1) and (M2), the step of fractionating the isomerized hydrocarbon stream comprises fractionating the isomerized hydrocarbon stream into the isomerate product stream in a fractionation overhead, a fractionation bottoms stream, and the hexane-containing raffinate stream in a fractionation side draw. The method (M1) further comprises: fractionating the hexane-depleted raffinate stream in the presence of the isomerized hydrocarbon stream; and combining the hexane-depleted raffinate stream and the isomerate product stream. In the method (M1), the step of fractionating the isomerized hydrocarbon stream further comprises fractionating the isomerized hydrocarbon stream into a recycle stream comprising unbranched hydrocarbons in another fractionation side draw separated from the hexane-containing raffinate stream. In the method (M2): the isomerate separation stage comprises an adsorption unit that preferentially adsorbs linear hydrocarbons over branched and cyclic hydrocarbons; the hexane separation stage comprises a second fractionation unit, where the step of separating the linear hexane stream comprises fractionating the hexane-containing raffinate stream into the hexane-depleted raffinate stream as an overhead pentane stream and the linear hexane stream as a second fractionation bottoms stream; the isomerate separation stage comprises a fractionation unit, where the hexane-containing raffinate stream comprises linear hexane, cyclic hydrocarbons and monomethyl-branched pentane, and the isomerate product stream comprises branched hydrocarbons having less than or equal to 6C and linear hydrocarbons having less than or equal to 5C; and the hexane separation stage comprises an adsorption unit that preferentially adsorbs linear hydrocarbons over branched and cyclic hydrocarbons, where the step of separating the linear hexane stream comprises adsorbing the linear hexane from a portion of the hexane-containing raffinate stream to produce the linear hexane stream and the hexane-depleted raffinate stream comprising cyclic hydrocarbons and monomethyl-branched pentane. EXAMPLE - No suitable example given.