NOVELTY - Pramipexole synthesis involves stirring anhydrous dioxane or tetrahydrofuran with (S)-2-propionylamino-4,5,6,7-tetrahydro-benzothiazole-6-carboxylic acid in a reaction kettle in presence of nitrogen gas at controlled temperature of 20-30 degrees C uniformly. The obtained produced is mixed with sodium borohydride, potassium borohydride or fatty acid to obtain mixed product. The obtained product is stirred and heated uniformly till all the reactants are completely dissolved and then purified water is added dropwise for controlling the temperature between 10-20 degrees C.    USE - Method for synthesis pramipexole (claimed).    ADVANTAGE - The method enables to syntheses pramipexole in a non-toxic and eco-friendly manner.    DETAILED DESCRIPTION - Pramipexole synthesis involves stirring anhydrous dioxane or tetrahydrofuran with (S)-2-propionylamino-4,5,6,7-tetrahydro-benzothiazole-6-carboxylic acid in a reaction kettle in presence of nitrogen gas at controlled temperature of 20-30 degrees C uniformly. The obtained produced is mixed with sodium borohydride, potassium borohydride or fatty acid to obtain mixed product. The obtained product is stirred and heated uniformly till all the reactants are completely dissolved and then purified water is added dropwise for controlling the temperature between 10-20 degrees C. The obtained product is washed with a solution of 10% of sodium hydroxide and then extracted 3-4 times with ethyl acetate. The extracted organic phases are combined and dried over anhydrous sodium sulfate for 10-12 hours. The obtained filtered solution is dried at reduced pressure at 40-50 degrees C to form precipitates, which are separated by suction filtration at 45-50 degrees C and then dried for 10-12 hours. The reaction kettle is cleaned and obtained precipitates are mixed in it with ethanol to obtain a clear solution. Water is added dropwise in the clear solution with hydrochloric acid at 15-20 degrees C. The obtained product is incubated for 3-4 hours for crystallization to obtain desired product.