NOVELTY - A mixture of hydrocarbon ketones is produced by contacting acetone and greater than or equal to 2 primary alcohols with catalyst and optionally base in which catalyst contains greater than or equal to 1 metals and hydrotalcite (HT), lanthanum oxide (La2O3), titanium dioxide (TiO2), and/or magnesium oxide (MgO).    USE - Production of mixture of hydrocarbon ketones for fuel composition (claimed).    ADVANTAGE - In situ inhibitory metabolites produced during fermentation are removed using selective, non-toxic, water-immiscible extractant, increasing solvent titers and yield, lowering distillation costs, and reducing water usage and reactor sizes.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for:    (1) production of a mixture of hydrocarbon ketones which involves contacting acetone and greater than or equal to 2 primary alcohols with catalyst and optionally base in which catalyst contains palladium-copper (Pd-Cu)/HT, Pd-Cu/HT-C, Pd-Cu/HT/C, Pd/HT, Cu/HT, copper/zinc oxide/aluminum oxide (Cu/ZnO/Al2O3), hydroxyapatite, perovskite, Cu/MgO, (Cu/ZnO/Al2O3)/HT, barium oxide/silicon dioxide (BaO/SiO2), MgO/SiO2, strontium oxide (SrO)/SiO2, calcium oxide (CaO)/SiO2, SrO/MgO, CaO/MgO, Pd-Cu/NiHT, Cu/NiHT, PdCu/ZnHT, Cu/ZnHT, PdCu/ZnHT, ruthenium (Ru)/HT, Cu-Ru/HT, cobalt (Co)/HT, platinum (Pt)/HT, Pt-Cu/HT, Cu/SiO2, Pd/C, CaO/C, SrO/C, BaO/C, La2O3/C, cerium dioxide (CeO2)/C, HT/C, HT, CeO2, La2O3, TiO2, and/or zeolite;    (2) production of a mixture of hydrocarbon ketones which involves contacting secondary alcohol and greater than or equal to 1 primary alcohols with metal catalyst and optionally base;    (3) production of a mixture of hydrocarbon ketones which involves contacting biomass or sugars with fermentation host to produce fermentation product mixture consisting of isopropanol, butanol, and ethanol, isolating at least a portion of isopropanol, butanol, and ethanol from fermentation product mixture, and contacting isolated isopropanol, butanol, and ethanol with metal catalyst and optionally base;    (4) production of a mixture of hydrocarbon ketones which involves contacting biomass or sugars with fermentation host to produce fermentation product mixture consisting of acetone, butanol, and ethanol, isolating at least a portion of acetone, butanol, and ethanol from fermentation product mixture, and contacting isolated acetone, butanol, and ethanol with metal catalyst and optionally base in which greater than or equal to 20% of the mixture of hydrocarbon ketones are greater than or equal to 7 carbon-containing hydrocarbon ketones;    (5) production of a mixture of hydrocarbon ketones which involves contacting greater than or equal to 2 alcohols with metal catalyst and optionally base in which greater than or equal to 1 of the greater than or equal to 2 alcohols is an acetone precursor; and    (6) composition comprising gasoline fuel, jet fuel, and/or diesel fuel and greater than or equal to 1 hydrocarbon ketones.    DESCRIPTION OF DRAWING(S) - The drawing shows a graph of the effect of water on the product and overall yields of alkanones produced in an acetone-butanol-ethanol (ABE) reaction.