NOVELTY - Producing biodiesel from biolipids comprises: mixing the biolipids with a low-molecular weight alcohol and a catalyst to obtain a two phase, liquid-liquid fluidic reaction mixture; providing a flow-path through a hydrodynamic cavitation device; pumping the fluidic reaction mixture through a multi-jet nozzle in flow-path, where multi-jet nozzle creates cavitation features in fluidic reaction mixture; passing the fluidic reaction mixture through many spiral guides disposed in a working chamber in flow-path; and conveying the fluidic reaction mixture through many flow guides in a vortex chamber.    USE - The method is useful for producing biodiesel from biolipids, where the biolipids comprise crude or preliminarily treated plant oil, including canola oil, castor bean oil, coconut oil, corn oil, cotton oil, hemp oil, Jatropha oil, linseed (flax seed) oil, mustard seed oil, nut oil, olive oil, palm oil, peanut oil, rapeseed oil, safflower oil, soybean oil, sunflower oil or tall oil, algal oil, fish oil, animal fat, including grease, lard, tallow and waste fat, bird fat, and any oil produced by using wild-type or genetically modified bacteria, yeast, fungi or other live unicellular or multicellular organisms, and the biodiesel comprises a fatty acid lower alkyl ester (all claimed).    ADVANTAGE - The method: does not require high energy input as the cavitation device is static (i.e. it does not contain moving parts), thus requiring minimum input fluid velocity and pressure to create cavitation in the flow towards the goal of creating new products with increased yield and quality.    DETAILED DESCRIPTION - Producing biodiesel from biolipids comprises: mixing the biolipids with a low-molecular weight alcohol and a catalyst to obtain a two phase, liquid-liquid fluidic reaction mixture; providing a flow-path through a hydrodynamic cavitation device; pumping the fluidic reaction mixture through a multi-jet nozzle in the flow-path, where the multi-jet nozzle has many channels, and the multi-jet nozzle creates cavitation features in the fluidic reaction mixture; passing the fluidic reaction mixture through many spiral guides disposed in a working chamber in the flow-path, where the spiral guides create cavitation features in the fluidic reaction mixture; conveying the fluidic reaction mixture through many flow guides in a vortex chamber, where the flow guides and vortex chamber create cavitation features in the fluidic reaction mixture; reacting the biolipids with the low-molecular weight alcohol in each of the pumping, passing and conveying steps to produce the biodiesel and a glycerol; and separating the biodiesel from the glycerol.