TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Compositions: Substituent number is 1 or 2. Halogen is fluorine (F), chlorine (Cl), or bromine (Br), 1-4 carbon (1-4C) alkyl is methyl or propyl. Solvent is toluene, dichloromethane, acetonitrile, tetrahydrofuran (THF), or dimethylformamide (DMF), preferably toluene. Molar ratio aromatic aldehyde:VB1: alpha , beta -unsaturated aldehyde:chiral sec.-amine catalyst:acid is 2:0.3-0.5:0.6-0.8:0.1-0.2:1.5-2, preferably 2:0.3:0.7:0.2:1.8. Mass ratio resulting product:oxidant is 1:1-2, reaction temperature is 30-50 degrees C, solvent is toluene, dichloromethane, acetonitrile, THF, or DMF, preferably dichloromethane. Preferred Processes: Primary separation and purification are performed by taking reaction solution, removing solvent, isolating residue using silica gel column, and eluting with eluent in which eluent is petroleum ether and ethyl acetate with ratio of 10-30:1, preferably 15-20:1, and secondary separation and purification are performed by taking reaction solution, isolating residue using silica gel column, and eluting with eluent in which eluent is petroleum ether and ethyl acetate with ratio of 50-80:1, preferably 50-60:1. Benzaldehyde-containing compound of formula (Ia) is obtained by adding benzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, chlorobenzaldehyde-containing compound of formula (Ib) or formula (Ic) is obtained by adding chlorobenzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, bromobenzaldehyde-containing compound of formula (Id) or formula (Ie) is obtained by adding bromobenzaldehyde, VB1, acetonitrile, sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, continuously reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, fluorobenzaldehyde-containing compound of formula (If) is obtained by fluorobenzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, continuously reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, 2,4-chlorobenzaldehyde-containing compound of formula (Ig) is obtained by adding 2,4-chlorobenzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, isopropylbenzaldehyde-containing compound of formula (Ih) is obtained by adding isopropylbenzaldehyde, VB1, acetonitrile, sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, furfural-containing compound of formula (Ii) is obtained by adding furfural, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent thiophenecarboxaldehyde-containing compound of formula (Ij) is obtained by adding thiophenecarboxaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, benzaldehyde-containing compound of formula (Ik) is obtained by adding benzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding p-chloro cinnamaldehyde, diphenyl diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, benzaldehyde-containing compound of formula (Il) is obtained by adding benzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding bromocinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, benzaldehyde-containing compound of formula (Im) is obtained by adding benzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding fluorocinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, benzaldehyde-containing compound of formula (In) is obtained by adding benzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding p-methyl cinnamaldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, chlorobenzaldehyde-containing compound of formula (Io) is obtained by adding chlorobenzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding acrolein, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent, and chlorobenzaldehyde-containing compound of formula (Ip) is obtained by adding chlorobenzaldehyde, VB1, acetonitrile, and sodium hydroxide aqueous solution, adjusting pH to 9-10, stirring, reacting at 50-70 degrees C, balancing reaction, adding aldehyde, diphenylprolinol silyl ether, benzoic acid, and toluene, reacting at 80-120 degrees C, removing solvent under reduce pressure, putting residue into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 10-30:1, tracking film, combining eluent, removing solvent, purifying resulting product and pyridinium chlorochromate into dichloromethane, performing oxidation reaction, putting into silica gel column, eluting with petroleum ether and ethyl acetate with ratio of 50-80:1, tracking film, combining eluent, and removing solvent. Preferred Definitions:    R1=Ph, substituted Ph, or O or S-containing 5-membered aromatic heterocyclic radical;    R2=H, Me, Ph, or substituted Ph which is halo substituent or 1-4C alkyl;    R3=trimethylsilyl, triethylsilyl, or tri-tert.-silicon; and    R4-R5=phenyl.    SPECIFIC COMPOUNDS - 16 Specific compounds are prepared e.g. (4S,5S)-5-benzoyl-4,5-diphenyl-dihydro-furan-2-one (Ia), (4S,5S)-5-(4-fluoro-benzoyl)-5-(4-fluoro-phenyl)-4-phenyl-dihydro-furan-2-one, (4S,5S)-5-(4-isopropyl-benzoyl)-5-(4-isopropyl-phenyl)-4-phenyl-dihydro-furan-2-one, (4S,5S)-5-benzoyl-4-(4-bromo-phenyl)-5-phenyl-dihydro-furan-2-one and (4R,5S)-5-benzoyl-4-methyl-5-phenyl-dihydro-furan-2-one.