NOVELTY - The system has a processor coupled to an aerosol flame reactor and to process instruments. The processor executes programmed instructions stored in a memory for feeding simulated flame dynamics data from a flame dynamics model to a continuous population balance model and for processing a mean particle size and a specific surface area of nanoparticles for optimizing and controlling the mean particle size and the specific surface area and for scale up of a nanoparticle production in the flame reactor by changing the operating data, burner design parameters and burner configuration (Flame-B).    USE - System for optimizing and controlling properties e.g. mean particle size and specific surface area, of nanoparticles e.g. titanium dioxide nanoparticles, silicon dioxide nanoparticles, carbon black nanoparticles, aluminum oxide nanoparticles, and zinc oxide nanoparticles (all claimed), for scaling up of nanoparticle production in an aerosol flame reactor for fundamental and practical applications. Uses include but are not limited to electronic applications, electric applications, magnetic chemical applications and mechanical polishing applications, coating applications, data storage applications, fuel cells applications, and industrial and domestic product applications such as tires applications, printing ink applications, paint and pigment applications, plastic applications, optical fiber applications, catalyst applications, pharmaceutical ingredient applications and cosmetic applications.    ADVANTAGE - The system is capable of optimizing and controlling the particle size distribution of nanoparticles in an efficient manner, and scale-up of production of nano-particles with desired properties in a cost effective and time saving manner. The system is capable of reducing a number of trials or experiments to be conducted for scale-up, and providing details about an internal condition of the process equipment and insight into a phenomena that occur during the process and providing a simulation tool with programmed instructions for production of nano-particles with controlled properties.    DETAILED DESCRIPTION - The simulated flame dynamics data is temperature data, pressure or velocity data, and chemical composition of gaseous phase. The process instruments are selected from a group consisting of a precursor flow rate gauge, precursor pressure gauge, air or oxidant flow rate gauge, air or oxidant pressure gauge, carrier gas flow rate gauge, carrier gas pressure gauge, fuel flow rate gauge, fuel pressure gauge, and temperature sensor.    DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of a structure illustrating temperature contours and a value of an alumina aggregate particle size inside a flame reactor with burner configuration.    Burner configuration (Flame-B)