TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Process: The process further comprises filtering and washing the product of the condensation. The process-I further comprises filtering, washing, and drying the crystalline material. The crystallization is performed by dissolving olanzapine in 1-4C alcohol at 40-60 degrees C and adding water dropwise at 15-25 degrees C. The condensation is performed at 100-130 degrees C for 3-5 hours. Preferred Components: The second solvent is ethanol. The volume ratio of the first solvent and the second solvent is 1:1-5:1. The 1-4C alcohol is 1-propanol or ethanol. The volume ratio of the 1-4C alcohol and water is 1:0.5-1:2.    TECHNOLOGY FOCUS - PHARMACEUTICALS - Preferred Components: The salt of 4-amino-2-methyl-10H-thieno(2,3-b)(1,5)benzodiazepine is 4-amino-2-methyl-10H-thieno(2,3-b)(1,5)benzodiazepine hydrochloride. The purity of the prepared olanzapine is greater than 99%. The purity of the olanzapine crystalline form-II is greater than 99.9%. ACTIVITY - Neuroleptic; Tranquilizer; Antimanic.    MECHANISM OF ACTION - None given.    EXAMPLE - 50 g of 4-Amino-2-methyl-10H-thieno-(2,3-b)(1,5)benzodiazepine hydrochloride was mixed with 300 ml of dimethylsulfoxide and 100 ml of ethanol and stirred in a mixture of 320 ml of N-methylpiperazine at an internal temperature of 100-130 degrees C for 3-5 hours. Upon completion of the reaction, the mixture was cooled to room temperature, 200 ml of ethanol was added, and then purified 500 ml of water was added. The mixture was stirred at 0-5 degrees C for 1 hour, and the resulting solids were filtered and washed with ethanol/water (1:1x 10). The obtained solids were dried in a vacuum oven at 50 degrees C for 12-24 hours to give 54.6 g of olanzapine. The 1 g of obtained olanzapine was completely dissolved in 20 ml of 1-propanol by heating at 45-55 degrees C and cooled to room temperature. 20 ml of Purified water was slowly added dropwise to the mixture to produce crystalline solids at room temperature for 1 hour. The resulting crystalline solids were filtered and dried in a vacuum oven at 60 degrees C for 48 hours to give 0.83 g of high-purity olanzapine crystalline form-II 0.83 g.