TECHNOLOGY FOCUS - PHARMACEUTICALS - Preferred Method: In the step of forming first-stage seed liquid culture conditions are as follows: culture temperature of Bacillus subtilis is 30 to 40 degrees C, the culture time is 24 to 48 hours, culture temperature of Bacillus licheniformis is 30 to 40 degrees C and the culture time is 24 to 48 hours, culture temperature of a Trichoderma koningii is 25-32 degrees C, and the culture time is 72 to 96 hours, yellow Phanerochete chrysosporium culture temperature is 35-42 degrees C, culture time is 72 to 96 hours, for Bacillus laterosporus culture temperature is 38 to 50 degrees C, the culture time is 72 to 96 hours, for Clostridium thermocellum culture temperature is 30 to 37 degrees C, and the culture time is 24 to 48 hours. Preferred Components: The strain combination comprises Bacillus subtilis, Bacillus licheniformis, Phanerochete chrysosporium; Tichoderma koningii and Clostridium thermocellum in weight ratio of 2.0 to 2.5:2.0 to 2.5:1.0 to 2.0:2.0 to 3.0:2.0 to 3.0. The inclined plane culture medium formulation of Bacillus subtilis inclined plane culture base having beef extract (5 g/l), peptone (10 g/l), sodium chloride (5 g/l), agar powder (20 g/l), is prepared by combining the components, adjusting the pH value to neutral, and sterilizing. The Bacillus licheniformis inclined plane culture base includes beef extract (5 g/l), peptone (10 g/l), sodium chloride (5 g/l), agar powder (20 g/l), and is prepared by combining the components, adjusting the pH value to neutral, and sterilizing. The Trichoderma koningii inclined plane culture base includes grass powder (60 to 80 g/l), ammonium sulfate (25 to 35 g/l), potassium dihydrogen phosphate (4 to 8 g/l), magnesium sulfate (2 to 8/l), 0.1-0.3 g/l of calcium chloride, and is prepared by combining the components, regulating pH value to be 6 to 7, adding 15 g/l of agar, heating at 60 to 100 degrees C, melting, pouring into a disk, cooling and cutting into strips, putting into bottle, and sterilizing. Phanerochete chrysosporium inclined plane culture base is prepared by boiling wheat bran (120 to 140 g/l), filtering using yarn cloth filter, adding cane sugar (10 to 15 g/l), adjusting neutral pH, and adding to it 20 g/l of agar, sterilizing. Sporosarcina psychropilus inclined plane culture base is prepared by mixing beef extract (5 g/l), peptone (10 g/l), sodium chloride (5 g/l), agar powder (20 g/l), adjusting the pH value to neutral, and sterilizing. Clostridium thermocellum inclined plane culture base is prepared by mixing beef extract (5 g/l), peptone (10 g/l), sodium chloride (5 g/l), agar powder (20 g/l), and adjusting the pH value to neutral. Bacillus laterosporus inclined plane culture base is prepared by mixing beef extract (5 g/l), peptone (10 g/l), sodium chloride (5 g/l), agar powder (20 g/l), adjust pH value to neutral, and sterilizing.