NOVELTY - Extracting hesperidin from orange peel, comprises (i) crushing the dried orange peel; (ii) extracting the crushed raw material, and removing volatile oil and fat-soluble components; (iii) extracting the medicinal slag powder, adding ethanol, adjusting the pH to 4.5-6 by adding hydrochloric acid, and adding 0.02-0.04% cellulase, and placing the extractor in ultrasonic conditions, and extracting; and (iv) centrifuging the extraction liquid, concentrating, dissolving with alkali with ethanol solution, filtering, adding acid to neutralize, separating out the precipitate, and re-crystallizing.    USE - The method is useful for extracting hesperidin from orange peel (claimed).    ADVANTAGE - The method has simple process, and high production yield; produces high purity product; shortens extracting time; and is environmental friendly, and suitable for industrial mass production.    DETAILED DESCRIPTION - Extracting hesperidin from orange peel, comprises (i) crushing the dried orange peel, and passing by 80 items sieve; (ii) extracting the crushed raw material by placing in a supercritical extractor, where the extraction temperature is 50-70 degrees C, the analytical pressure is 8-12 MPa, analytical temperature is 30-50 degrees C, the extraction pressure is 20-30 MPa, and the extraction time is 1-2 hours, and removing volatile oil and fat-soluble components; (iii) extracting the medicinal slag powder by passing supercritical carbon-dioxide, adding 50-70% ethanol in an amount of 5-8 times, adjusting the pH to 4.5-6 by adding hydrochloric acid, and adding 0.02-0.04% cellulase, and placing the extractor in ultrasonic conditions, where the ultrasonic power is 150-200 W, and extracting for 80-100 minutes at 40-50 degrees C; and (iv) centrifuging the extraction liquid of the step (iii), taking out supernatant fluid, concentrating under reduced pressure, and dissolving the concentrate by adding alkali with ethanol solution, filtering, adding acid to neutralize, separating out the precipitate, collecting the precipitate, re-crystallizing with ethanol, washing, and drying to obtain the product.