NOVELTY - ((S)-(4-(Methylsulfonyl)phenyl)((R)-1-aziridin-2-yl)methanol) (B) (II) and triethylamine salt of hydrofluoric acid are added, and heated to obtain (1S,2S)-3-fluoro-1-(4-(methylsulfonyl)phenyl)-2-(amino)-1-propanol (C). Compound (C) is dissolved in solvent, hydrogenated in presence of palladium-carbon catalyst, and deprotected to obtain (1S,2S)-2-amino-3-fluoro-1-(4-(methylsulfonyl)phenyl)-1-propanol (D). Compound (D) is subjected to acylation and cyclization reaction to obtain dihydrooxazole compound (III). Dihydrooxazole compound (III) is acid-hydrolyzed to obtain florfenicol.    USE - Synthesis of florfenicol (claimed).    ADVANTAGE - The method enables safe industrial synthesis of florfenicol by simple, economical and environmentally-friendly process, with reduced equipment corrosion. Wastewater treatment cost is reduced.    DETAILED DESCRIPTION - 2-Bromo-3-chloro-1-(4-(methylthio)phenyl)-1-propanone is dissolved in organic solvent, catalyst and hydrogen peroxide are added and reacted to obtain 2-bromo-3-chloro-1-(4-(methylsulfonyl)phenyl)-1-propanone. A mixture of 2-bromo-3-chloro-l-(4-(methylsulfonyl)phenyl)-1-propanone, chiral amine of formula: R1-NH2 (a) and alkali dissolved in solvent are reacted at 0-80 degrees C to obtain non-enantiomer of chiral amino ketone compounds. Non-enantiomer of chiral amino ketone compound is subjected to physical separation to obtain 1-R1-2-(R)-(4-(methylsulfonyl)phenyl) carbamoyl aziridine compound (A) of formula (I). Compound (A) is dissolved in organic solvent, cooled, reducing agent and Lewis acid are added, and reacted to obtain chiral amino alcohol compound ((S)-(4-(methylsulfonyl)phenyl)((R)-1-R1-aziridin-2-yl)methanol) (B) of formula (II). Compound (B) and triethylamine salt of hydrofluoric acid are added to solvent (s5), and heated to obtain (1S,2S)-3-fluoro-1-(4-(methylsulfonyl)phenyl)-2-(R1-amino)-1-propanol (C). Compound (C) is dissolved in solvent, hydrogenation reaction is carried out in presence of palladium-carbon catalyst, and deprotected to obtain (1S,2S)-2-amino-3-fluoro-1-(4-(methylsulfonyl)phenyl)-1-propanol (D). Compound (D) is subjected to acylation reaction and cyclization reaction to obtain dihydrooxazole compound of formula (III). Dihydrooxazole compound (III) is acid-hydrolyzed to obtain florfenicol.    R1=(S)-1-phenylethyl or (R)-1-phenylethyl;and    R2=phenyl, dichloromethyl or hydroxy.