NOVELTY - Preparing ticagrelor intermediate 4,6-dichloro-5-amino-2-propylthio-pyrimidine (I), comprises e.g. (i) dissolving 4,6-dichloro-5-nitro-2-propylthio-pyrimidine (VI) in a reaction solvent, then adding a dechlorination inhibitor and a metal catalyst, and carrying out reduction reaction in presence of hydrogen gas, (ii) filtering the reacted mixture, washing, and drying to obtain crude product of (I), and (iii) recrystallizing the obtained crude product with an organic solvent to obtain pure product i.e. (I), where weight ratio between the crude product and the organic solvent is 1 g:1-30 ml.    USE - The method is useful for preparing ticagrelor intermediate 4,6-dichloro-5-amino-2-propylthio-pyrimidine (claimed).    ADVANTAGE - The method: is simple and environment-friendly; has low production cost; and solves problems of existing method.    DETAILED DESCRIPTION - Preparing ticagrelor intermediate 4,6-dichloro-5-amino-2-propylthio-pyrimidine of formula (I), comprises (i) dissolving 4,6-dichloro-5-nitro-2-propylthio-pyrimidine of formula (VI) in a reaction solvent, then adding a dechlorination inhibitor and a metal catalyst, and carrying out reduction reaction in presence of hydrogen gas, where the reaction solvent is toluene, tetrahydrofuran, N,N-dimethylformamide, N,N-diethylformamide, dimethyl sulfoxide, dioxane, methyl tert-butyl ether, methanol, ethanol, propanol, isopropanol and/or water, mass ratio between 4,6-dichloro-5-nitro-2-propylthio-pyrimidine and the reaction solvent is 1 g:1-20 ml, the dechlorination inhibitor is triethylenetetramine, cyclohexylamine, dicyandiamide, diethanolamine and/or 2-aminothiazole, weight ratio between 4,6-dichloro-5-nitro-2-propylthio-pyrimidine and the dechlorination inhibitor is 100:0.1-15; the metal catalyst is palladium/carbon or Raney nickel, and mass ratio between 4,6-dichloro-5-nitro-2-propylthio-pyrimidine and the metal catalyst is 100:0.1-20, (ii) filtering the reacted mixture, washing, and drying to obtain crude product of (I), and (iii) recrystallizing the obtained crude product with an organic solvent to obtain pure product i.e. (I), where weight ratio between the crude product and the organic solvent is 1 g:1-30 ml.