NOVELTY - An isolated bacterial, fungal or yeast cell (C1) comprising the following genetic modifications: plasmid expression of a fucO-cpA construct or chromosomal integration of a fucO-ucpA construct into the gene encoding acetate kinase (ackA) of the bacterial, fungal or yeast cell in combination with the deletion of the gene encoding yqhD or chromosomal integration of a gene encoding pntAB behind the adhE promoter (adhE::pntAB), is new.    USE - For producing a desired product from a biomass, a hemicellulosic biomass, a lignocellulosic biomass, a cellulosic biomass or an oligosaccharide source, where the desired product is selected from ethanol, lactic acid, succinic acid, malic acid, acetic acid, 1,3-propanediol, 2,3-propanediol, 1,4-butanediol, 2,3-butanediol, butanol, pyruvate, dicarboxylic acids, adipic acid and amino acids (all claimed).    ADVANTAGE - The bacterial, fungal or yeast cell exhibits increased production of a desired product as compared to a reference bacterial, fungal or yeast cell in the presence of furfural and/or 5-hydroxymethylfurfural (5-HMF). The isolated bacterial, fungal or yeast cell produces desired product in the presence of 5-40 mM, 5-20 mM, 15-30 mM, or 15 mM furfural and/or 5-HMF. The bacterial, fungal or yeast cells exhibit increased furfural and 5-HMF tolerance and increased tolerance to toxins in hemicellulose hydrolysates.    DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following:    (1) new isolated ethanologenic or succinate producing bacterial strain comprising the following genetic modifications: plasmid expression of a fucO-ucpA construct or chromosomal integration of a fucO-ucpA construct into the gene encoding acetate kinase (ackA) of the bacterial strain in combination with the deletion of the gene encoding yqhD or chromosomal integration of a gene encoding pntAB behind the adh.E promoter (adhE::pntAB);    (2) method of growing a bacterial, fungal or yeast cell;    (3) producing a desired product from a biomass, a hemicellulosic biomass, a lignocellulosic biomass, a cellulosic biomass or an oligosaccharide source involving contacting the biomass, hemicellulosic biomass, lignocellulosic biomass, cellulosic biomass or oligosaccharide with the isolated bacterial, fungal or yeast cell and producing the desired product by fermenting the biomass, hemicellulosic biomass, a lignocellulosic biomass, a cellulosic biomass or an oligosaccharide source in the presence of the bacterial, fungal or yeast cell; and    (4) increasing furfural and/or 5-hydroxymethylfurfural (5-HMF) resistance in a bacterial, fungal or yeast cell involving introducing the following genetic modifications to the bacterial, fungal or yeast cell: plasmid expression of a fucO-ucpA construct or chromosomal integration of a fucO-ucpA construct into the gene encoding acetate kinase (ackA) of the bacterial, fungal or yeast cell in combination with the deletion of the gene encoding yqhD or chromosomal integration of a gene encoding pntAB behind the adhE promoter (adhE::pntAB).