NOVELTY - A quercetin is separated and purified using simulated moving bed chromatography by dissolving quercetin crude product in mobile phase to obtain 10 mg/ml concentration, injecting to chromatographic system using sampling pump in which chromatographic system is composed of 12 preparative columns and divided into 3 areas, and periodically controlling opening and closing of electromagnetic valve to ensure inlet of mobile phase, outlet of extract solution, and outlet of raffinate along mobile phase using system controller to obtain product quercetin in extract solution outlet.    USE - Separating and purifying quercetin using simulated moving bed chromatography (claimed).    ADVANTAGE - Process is simple and environment-friendly, has continuous and automatic production, and improved production efficiency, produces stable and high purity product, uses recyclable solvent, and realizes clean production.    DETAILED DESCRIPTION - A quercetin is separated and purified using simulated moving bed chromatography by using simulated moving bed chromatographic system comprising eluting pump, sampling pump, extracting pump, chromatographic column, electromagnetic valve, 1-way valve, controller, and computer in which flowrate in eluting pump is 0-50 ml/minute and pressure is 0-40 MPa, flowrate in sampling pump is 0-10 ml/minute and pressure is 10-10 MPa, flowrate in extracting pump is 0-50 ml/minute and pressure is 0-40 Mpa, working temperature is 20-40 degrees C, and chromatographic column stationary phase is octadecyl silica bonded silica, filler particle size 10-20 mu m, and mobile phase is mixture of methanol and water, dissolving quercetin crude product in mobile phase to obtain 10 mg/ml concentration, injecting to chromatographic system using sampling pump in which chromatographic system is composed of 12 preparative columns and divided into 3 areas, periodically controlling opening and closing of electromagnetic valve to ensure inlet of mobile phase, outlet of extract solution, and outlet of raffinate along mobile phase using system controller to obtain product quercetin in extract solution outlet, generating quercetin product solution, concentrating, crystallizing, filtering, and drying to obtain product with greater than or equal to 90% purity in which end product HPLC assay uses NewstyleNP7000 pump as detecting pump, 4.6x 250 mm, 5 mu m, C18 as chromatographic column, hanboss UV detector NeWStyleNU3000 as detector, 210 nm as detection wavelength, room temperature as detection temperature, and methanol and water with 1 ml/minute flowrate and volume ratio of 60:40 as mobile phase.