TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Method: The method involves contacting the feedstock of biological origin sequentially with the first catalyst in a first zone of the reactor and with the hydrogenation catalyst in a second zone of the reactor. The method involves contacting the feed sequentially with the acidic catalyst in a first zone of the reactor and with the hydrogenation catalyst in a second zone of the reactor. Preferred Components: The hydrofinishing catalyst is selected from noble metals on carbon, silica, alumina and MCM-41 support. The hydrothermally stable binder comprises TiO2, ZrO2 or CeO2. The first catalyst comprises a basic material. The first catalyst has a ratio of CO2 chemisorption to NH3 chemisorption of 1-100. The first catalyst is selected from basic clay, alkali impregnated support, and basic metal oxide. The first catalyst comprises a basic catalyst selected from hydrotalcite; basic metal oxide selected from MgO, CaO, BaO, ZnO, MnO2 and K2CO3 supported on SiO2 or ZrO2; K2CO3 supported on TiO2; and La2O3, CeO2, Y2O3, Sm2O3, Pr2O3, La2O3/ZrO2, ZnO/La2O3, Y2O3/ZrO2, CeO2/ZrO2, or La2O3/SiO2. The hydrogenation catalyst comprises a noble metal supported on zeolites. The hydrogenation catalyst comprises a metal hydrogenation component selected from Ni, Co, Pd, Pt, Ru, Rh, Co-Mo, Ni-Mo, Ni-W, and Co-W supported on an inorganic support selected from silica, alumina, titania, zirconia, and zeolites. The hydrogenation catalyst comprises Pt supported on zeolite. The zeolite comprises framework SiO2/Al2O3 ratio greater than 50:1. The zeolite component of the hydrogenation catalyst comprises zeolite selected from beta zeolite, USY family zeolite, mordenite, MCM-41, ZSM-22, ZSM-12, ZSM-23, ZSM-4, ZSM-48 and ZSM-50. The first catalyst is selected from La2O3/ZrO2, La2O3/ZnO and Y2O1/ZrO2, where the hydrogenation catalyst is Pt supported on ZSM-48 or ZSM-48/NiWOx, where the hydrothermally stable binder is selected from TiO2 and ZrO2. The first catalyst comprises an acidic material. The first catalyst has a ratio of CO2 chemisorption to NH3 chemisorption of 0.05-0.5. The first catalyst is selected from acidic clay, alumina, aluminosilicate, and metalloaluminophosphate. The first catalyst is selected from acidic metal oxide, mixed metal oxide, WO3/ZrO2, MoO3/ZrO2, zeolite of the faujasite, beta, or MWW family, 10-ring zeolite, 8-ring zeolite, a metalloaluminophosphate comprising Si, Ti, Zr, Fe, Co, Ni, Cu, Zn, Y, La, Ce, Pr, Nd, Sm or Gd. The second catalyst comprises a metal hydrogenation component selected from Ni, Co, Pd, Pt, Ru, Rh, Co-Mo, Ni-Mo, Ni-W, and Co-W and an inorganic support selected from silica, alumina, titania, zirconia, and zeolite. The second catalyst comprises a hydroisomerization catalyst comprising Pt supported on zeolite. The first catalyst is selected from Montmorillonite, bentonite, and WOx/ZrO2, where the hydrogenation catalyst is selected from Ni or Pd supported on silica or carbon, Co-Mo or Co-W supported on gamma-alumina, and Ni-Mo or Ni-W supported on gamma-alumina, where the hydrothermally stable binder is selected from TiO2 and ZrO2. The first catalyst comprises both a basic material and an acidic material.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Method: The step a) is carried out by: a1) converting a feedstock of biological origin to a fatty acid; and a2) coupling at least two fatty acids to form a ketone or a dimer acid. The method further involves removing H2O, CO2 and/or a light hydrocarbon. The step b) further involves hydroisomerizing or cracking the hydrocarbon produced in step b) to produce lube base stock and transportation fuel, where the transportation fuel comprises a diesel fuel and a jet fuel. The method further involves: hydrofinishing the lube base stock in the presence a hydrofinishing catalyst, followed by vacuum distillating. The method involves providing the feedstock of biological origin as a solution in a hydrocarbon solvent. The steps a) and b) are carried out in a single reactor. The method is carried out at a temperature of 300-400 degrees C under H2 partial pressure of 500-800 psig. The method is carried out at a temperature of 250-350 degrees C under H2 partial pressure of 500-2000 psig. Preferred Fuel: The jet fuel and diesel fuel comprises 1-25% aromatics, 20-40% naphthenes, and 40-80% paraffins. Preferred Components: The feedstock of biological origin comprises at least one component selected from fatty acid, fatty acid ester, fatty alcohol, fatty olefin, mono-glyceride, di-glyceride, tri-glyceride, phospholipid and saccharolipid. The feedstock of biological origin is selected from rapeseed oil, soy bean oil, palm oil, camelina oil, jatropha oil, jojoba oil, fish oil, lard, beef tallow, and algae oil. EXAMPLE - No suitable example given.