NOVELTY - Producing oxygenated compounds from biomass-derived feedstock involves a) providing an aqueous feedstock (F1) comprising water, greater than or equal to 20 wt.% of first oxygenated hydrocarbons selected from monosaccharides, disaccharides, trisaccharides and/or oligosaccharides, 1-40 wt.% of second oxygenated hydrocarbons comprising sugar degradation products and ash comprises less than or equal to 75 part per millions (ppm) sulfur and less than or equal to 30 ppm phosphorus; and b) reacting the feedstock (F1) with hydrogen in the presence of catalyst comprising Group VIII metal, to produce reaction product comprising oxygenated compounds.    USE - For producing oxygenated compounds from biomass-derived feedstock (claimed) such as liquid fuels and chemicals.    ADVANTAGE - The method purifies biomass-derived feedstocks prior to conversion; is semi-tolerant to extractives and ash components; and provides a realistic alternative to petroleum feedstocks saving the costs such as capital expenditures on equipment and processing systems.    DETAILED DESCRIPTION - Method of producing oxygenated compounds from biomass-derived feedstock involves either: a) providing aqueous feedstock (F1) comprising water, greater than or equal to 20 wt.% of first oxygenated hydrocarbons selected from monosaccharides, disaccharides, trisaccharides and/or oligosaccharides, 1-40 wt.% of second oxygenated hydrocarbons comprising sugar degradation products and ash comprising less than or equal to 75 part per millions (ppm) sulfur and less than or equal to 30 ppm phosphorus; and b) reacting the feedstock with hydrogen in the presence of catalyst comprising Group VIII metal, to produce reaction product comprising oxygenated compounds selected from alcohol, ketone, cyclic ether, carboxylic acid, aldehyde, diol and polyol; or involves deconstructing biomass with deconstruction method to produce intermediate feedstock comprising oxygenated hydrocarbons, ash, extractives, lignin, lignin derivatives and solids, and treating the intermediate feedstock with treatment method to produce aqueous feedstock (F1).