NOVELTY - Substituted (E)-2-(4-(4-fluoro-phenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl)-vinyl compounds (A1) are new.    USE - (A1) are useful for synthesizing rosuvastatin calcium (claimed).    ADVANTAGE - (A1) provide chemically and stereochemically pure rosuvastatin calcium by simple, eco-friendly, inexpensive, reproducible and robust process.    DETAILED DESCRIPTION - Substituted (E)-2-(4-(4-fluoro-phenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl)-vinyl compounds (A1) of formulae (II) and (III) and their acid addition salts are new.P1, P2 = amino substituted or ester substituted moieties.    INDEPENDENT CLAIMS are also included for:    (1) N-(4-bromophenyl)-2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamide (IIIb);    (2) 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic (isobutyl carbonic)anhydride (IIIa);    (3) a crystalline form of (IIIb) characterized by its X-ray powder diffraction pattern and Fourier transform infrared spectroscopy (potassium bromide) as given in the specification;    (4) (3R,5S,E)-N-(4-bromophenyl)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonylamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enamide (IIa);    (5) a crystalline form of (IIa) characterized by its X-ray powder diffraction pattern and Fourier transform infrared spectroscopy (potassium bromide) as given in the specification;    (6) preparation of (IIa) comprising: (a) reacting tert-butyl 6-((1E)-2-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)ethenyl)-2,2-dimethyl-1,3-dioxane-4-acetate (V) in presence of base and solvent to give 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid (IV); (b) converting (IV) with substituted chloroester compounds of formula (Cl-COOR1) (VIII) to obtain an in situ of (IIIa) which is reacted with substituted aniline compounds of formula (IX) to give (IIIb) or its salt; and (c) reacting (IIIb) with an acid, solvent and base to obtain (IIa); and    (7) preparation of rosuvastatin calcium comprising reacting (IIa) with salts or solvents.    R1, R2 = alkyl, aryl (both optionally substituted with alkyl (optionally substituted), alkoxy, sulfoxy, H, halo, nitro or amino), H, halo or sulfoxy.