NOVELTY - A metal organic framework(MOF)-based hierarchical porous material (IPD-meso-MOF-1-9) has structure chosen from MIL-100(aluminum, iron, chromium, scandium and indium), MIL-53(aluminum), HKUST-1, DUT-5, DUT-4, MIL-101(chromium), MIL-101NDC(chromium), MIL-101BPDC(chromium) and MIL-110, comprises micropores in which structural features and pore aperture of micropores vary with respect to MOF-type, and contains MOF-nanoparticles with particle size of 120 nm or less. The microparticles are capable of generating desired interparticle mesopores of 2-50 nm under close conditions.    USE - Metal organic framework-based hierarchical porous material is used in adsorption and storage of gas e.g. sulfur-containing heterocyclic aromatic, aromatic hydrocarbons or heterocyclic aromatic hydrocarbons such as hydrogen, methane or carbon dioxide, purification of gasoline and diesel, and loading and immobilization of biological macromolecules e.g. biological enzymes or virus which are protein molecules or nucleic acid molecules (all claimed). Uses include but are not limited to catalysis, molecular separation and drug delivery.    ADVANTAGE - The metal organic framework-based hierarchical porous material is economical, has high thermal stability and favorable reproducibility.    DETAILED DESCRIPTION - A metal organic framework(MOF)-based hierarchical porous material (IPD-meso-MOF-1-9) has structure chosen from MIL-100(aluminum, iron, chromium, scandium and indium), MIL-53(aluminum), HKUST-1, DUT-5, DUT-4, MIL-101(chromium), MIL-101NDC(chromium), MIL-101BPDC(chromium) and MIL-110, comprises micropores in which structural features and pore aperture of micropores vary with respect to MOF-type, and contains MOF-nanoparticles with particle size of 120 nm or less. The microparticles are capable of generating desired interparticle mesopores of 2-50 nm under close or relatively close packing conditions. INDEPENDENT CLAIMS are included for the following:    (1) preparation of (MOF)-based hierarchical porous material, which involves providing reaction mass containing metal salt chosen from nitrate, sulfate, perchlorate, hydrochloride, hydrobromide, acetate and formate, benzene-1,3,5-tricarboxylic acid as ligand, and solvent for IPD-meso-MOF-1 (based on MOF of MIE-100(M) (a), where M is ferric ion, aluminum ion, chromium ion, scandium ion, and indium ion) (b). The reaction mass contains aluminum salt chosen from nitrate, sulfate and perchlorate, 1,4-p-phthalic acid and 2-X-substituted 1,4-p-phthalic acid (X-BDC) as organic ligand, and aluminum ion-BDC or X-BDC as solvent, where X is F, Cl, Br, I, nitrogen dioxide or amine for IPD-meso-MOF-2 (based on MOF of MIE-53(aluminum) (c). The reaction mass containing copper acetate, copper formate or copper propionate and benzene-1,3,5-tricarboxylic acid as ligand, and solvent for IPD-meso-MOF-3 (based on MOF of HKUST-1) (d). The reaction mass containing aluminum salt chosen from nitrate, sulfate and perchlorate, an organic ligand chosen from 2-nitro, 2-amino, 2,2-dinitro and 2,2-diamino-4,4-biphenyldicarboxylic acid, and solvent for IPD-meso-MOF-4 (based on MOF of DUT-5) (e). The reaction mass containing aluminum salt chosen from nitrate, sulfate and perchlorate, 2,6-naphthalenedicarboxylic acid as organic ligand, and solvent for IPD-meso-MOF-5 (based on MOF of DUT-4). The molar ratio ligand and solvent is 1.4:1:800-1400, reaction mass containing trivalent chromium salt chosen from nitrate, sulfate, perchlorate, hydrochloride, hydrobromide, acetate and formate, 1,4-p-phthalic acid or 2-X-substituted 1,4-p-phthalic acid (X-BDC) where X is fluorine, chlorine, bromine, iodine, nitrogen dioxide or amine as organic ligand, and solvent for IPD-meso-MOF-6 (based on MOF of MIL-101 (chromium)) (f). The molar ratio ligand and solvent is 1.2:1:800-1400, reaction mass containing trivalent chromium salt chosen from nitrate, sulfate, perchlorate, hydrochloride, hydrobromide, acetate and formate, 2,6-naphthalenedicarboxylic acid as organic ligand, and solvent for IPD-meso-MOF-7 (based on MOF of MIL-101 NDC (chromium)) (g). The molar ratio ligand and solvent is 1.2:1:800-1400, reaction mass containing trivalent chromium salt chosen from nitrate, sulfate, perchlorate, hydrochloride, hydrobromide, acetate and formate, organic ligand chosen from 4,4-biphenyldicarboxylic acid, 2-nitro-4,4-biphenyldicarboxylic acid, 2-amino-4,4-biphenyldicarboxylic acid, 2,2-dinitro-4,4-biphenyldicarboxylic acid and 2,2-diamino-4,4-biphenyldicarboxylic acid, and solvent for IPD-meso-MOF-8 (based on MOF having MIL-lOl topological structure formed by chromium(III) and BPDC) (h). The reaction mass contains aluminum nitrate, aluminum sulfate or aluminum perchlorate, benzene-1,3,5-tricarboxylic acid as ligand and solvent for IPD-meso-MOF-9(based on MOF of MIL-110) (i). The reaction solvent is 5C or less fatty alcohol or mixture of fatty alcohol and N,N-dimethylformamide or mixture of fatty alcohols. The materials (a-i) are synthesized by solvothermal method or microwave synthesis method. The stacking density of MOF-nanoparticles is regulated by adding tetraalkylammonium halide( where alkyl is chosen from methyl, ethyl, propyl, and butyl, and the halide is chloride or bromide) into the reaction mixture as filler to expand the interparticle pores or control over size of MOF-nanoparticles and allow them to closely pack in order to generate the hierarchical porous material (monolithic xerogel) comprising micropores and mesopores, which is as A-form material, and is IPD-meso-MOF-nA, where n is 1-9), sodium chloride nanoparticles with particle size of 50-500 nm are added into the reaction mixture to afford MOF-based hierarchical porous material (monolithic xerogel) comprising micropores, mesopores and macropores, which is B-form material, and is IPD-meso-MOF-nB, or sol/gel of IPD-meso-MOF-n is dried with supercritical carbon dioxide to afford the MOF-based hierarchical porous material (monolithic aerogel) comprising micropores, mesopores and macropores, which is IPD-meso-MOF-nC;    (2) process for regulating the size of mesopores of IPD-meso-MOF-nA materials;    (3) preparation of IPD-meso-MOF-nB, which involves adding sodium chloride nanoparticles into the reaction mixture;    (4) preparation of IPD-meso-MOF-nC, which involves carrying out supercritical CO2 extraction of sol/gel reaction mixture to obtain MOF-based material as aerogel; and    (5) use of MOF-based material IPD-meso-MOF-1-9 in adsorption and storage of gas, purification of gasoline and diesel, or loading and immobilization of biological macromolecules.