NOVELTY - Producing a renewable biofuel from a bio-oil feed stream and a treated bio-oil feed, comprises: (a) mixing at least a portion of the treated bio-oil feed with the bio-oil feed stream; (b) separating water and at least a portion of the heavy fraction; (c) subjecting the non-heavy fraction to deoxygenating in a hydrotreater to form a separated hydrotreated product; (d) optionally removing produced water from the separated hydrotreated product; (e) subjecting the separated product to fractionation to render oil and at least one hydrocarbon fraction; and (f) generating renewable biofuel.    USE - The process is useful for producing renewable biofuel from a bio-oil feedstream and a treated bio-oil feed (claimed).    ADVANTAGE - The process ensures the removal of undesirable component from the bio-oil thus improving the hydrotreating process and rendering quality products.    DETAILED DESCRIPTION - Producing a renewable biofuel from a bio-oil feed stream and a treated bio-oil feed, comprises: either (a) mixing at least a portion of the treated bio-oil feed with the bio-oil feedstream to form a bio-oil mixture, (b) separating water and at least a portion of the heavy fraction from the bio-oil mixture, (c) subjecting the non-heavy fraction of the bio-oil mixture to deoxygenation in a hydrotreater to form a separated hydrotreated product and, optionally, a partial deoxygenated intermediate and removing the separated hydrotreated product and the optional partial deoxygenated intermediate from the hydrotreater, (d) optionally removing produced water from the separated hydrotreated product, (e) subjecting the separated hydrotreated product to fractionation to render oil having a boiling point in excess of 650 degrees F and at least one hydrocarbon fraction having a boiling point less than 650 degrees F, and (f) generating renewable biofuel from the separated fractions, where the treated bio-oil feed is at least a portion of the separated hydrotreated product, or at least a portion of the at least one hydrocarbon fraction having a boiling point less than 650 degrees F, or a partial deoxygenated intermediate; or An INDEPENDENT CLAIM is included for producing a renewable biofuel from bio-oil, comprising (a1) mixing a bio-oil stream with a hydrotreated stream to render a bio-oil mixture, (b1) deoxygenating the bio-oil mixture in a hydrotreater having a catalytic hydrotreating bed, (c1) separating two or more hydrocarbon streams from the deoxygenated stream, and (d,) generating the renewable biofuel from at least one of the separated hydrocarbon streams of step (c1) where, prior to step (b1), materials capable of plugging the catalytic hydrotreating bed are removed from the bio-oil mixture, or (a2) mixing at least a partially deoxygenated hydrotreated bio-oil stream with a bio-oil feedstream in an in-line mixer to form a bio-oil mixture, (b2) removing at least a portion of materials having a boiling point in excess of 650 degrees F from the bio-oil mixture to render a separated bio-oil mixture, (c2) at least partially deoxygenating the separated bio-oil mixture of step (b2) in a hydrotreater having a catalytic hydrotreating bed, (d2) separating the product of step (c2) into one or more light hydrocarbon fractions and (e2) generating biofuel from one or more of the one or more light hydrocarbon fractions of step (d2), or (a3) mixing a bio-oil stream with a hydrotreated stream to form a bio-oil mixture, where the hydrotreated stream comprising a stream which, prior to being hydrotreated, is pre-treated to remove materials having a boiling point greater than 650 degrees F, (b3) removing materials having a boiling point greater than 650 degrees F from the bio-oil mixture to form a separated bio-oil mixture, (c3) hydrotreating the separated bio-oil mixture of step (b3) to produce a deoxygenated stream, (d3) separating from the deoxygenated stream one or more light hydrocarbon streams having a boiling point less than 650 degrees F and hydrocarbons having a boiling point in excess of 650 degrees F, and (e3) generating biofuel from at least a portion of the one or more separated light hydrocarbon streams of step (d3).