TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The catalyst in the step (d) comprises: a metal consisting of molybdenum, nickel, copper, tungsten, cobalt, palladium, platinum, or ruthenium; and a heterogeneous catalyst and/or a dispersed catalyst.    TECHNOLOGY FOCUS - INSTRUMENTATION AND TESTING - Preferred Components: One or more moving bed reactors and/or one or more slurry reactors are used instead of or in addition to one or more ebullating bed reactors.    TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Process: The step (a): further comprises removing minerals from the biomass material before pyrolyzing and/or the removal of minerals from the biomass-derived pyrolysis product after pyrolyzing; and is carried out in a pyrolysis reactor (104), where the biomass material is conveyed by a screw. In the step (a), a biomass-derived pyrolysis oil is separated from the biomass-derived pyrolysis product and is mixed with the petroleum-derived hydrocarbon composition in the step (b). In the step (c), the hydrocarbon-containing mixture is dewatered by evaporation that is carried out by flashing. The step (d) comprises supplying a feed (102)comprising the dewatered hydrocarbon-containing mixture together with one or more co-feeds to the one or more ebullating bed reactors and/or contacting the dewatered hydrocarbon-containing mixture with the catalyst in the presence of such one or more co-feeds. Preferred Components: The biomass material is a lignocellulosic material, which is washed, steam exploded, dried, roasted, torrefied and/or reduced in particle size before being pyrolyzed in the step (a). The petroleum-derived hydrocarbon composition in the step (b) comprises a vacuum gas oil, a heavy coker gas oil, an atmospheric residue (long residue), and/or a vacuum residue (short residue). The biomass-derived pyrolysis product and the petroleum-derived hydrocarbon composition are mixed in the step (b) in a weight ratio of pyrolysis product to petroleum-derived hydrocarbon composition of 10:90-20:80. The co-feed comprises petroleum-derived hydrocarbon composition, a lignocellulosic material and/or a cellulosic material. The reaction product in the step (d) comprises one or more cracked products. The reaction product obtained in the step (d) is subsequently fractionated to produce one or more product fractions. The product fractions are blended with one or more additional components to produce a biofuel and/or biochemical, optionally after being hydrotreated and/or hydroisomerized.